Related papers: A biomimetic kidney tubule model
This study provides a complete rheological characterization of 2D nanomaterial dispersions, employed as 2D-inks precursors in printed electronics. Three different 2D nanomaterials (molybdenum disulfide (MoS2), graphene, and hexagonal boron…
Three-dimensional Mesoporous bioactive glasses (MBGs) scaffolds has been widely considered for bone regeneration purposes and additive manufacturing enables the fabrication of highly bioactive patient-specific constructs for bone defects.…
The mechanical performance of plant fibres is linked to the presence of crystalline elements dispersed within an amorphous cohesive matrix. The more the crystalline reinforcement is aligned with the fibre axis, the better the mechanical…
It is widely recognized that the shape of epithelial cells is determined by the tension generated by the actomyosin cortex and the adhesion of cells to the substrate and to each other. To account for these biological and structural…
Investigating the cellular internalization pathways of single molecules or single nano-objects is important to understanding cell-matter interactions and to applications in drug delivery and discovery. Imaging and tracking the motion of…
Myotubes are multinucleated muscle fibers serving as key model systems for studying muscle physiology, disease mechanisms, and drug responses. Mechanistic studies and drug screening thereby rely on quantitative morphological readouts such…
Visualization of three-dimensional morphological changes in the subcellular structures of a biological specimen is one of the greatest challenges in life science. Despite conspicuous refinements in optical nanoscopy, determination of…
How do cells tune emergent properties at the scale of tissues? One class of such emergent behaviors are rigidity transitions, in which a tissue changes from a solid-like to a fluid-like state or vice versa. Here, we introduce a new way for…
Partial nephrectomy (PN) is common surgery in urology. Digitization of renal anatomies brings much help to many computer-aided diagnosis (CAD) techniques during PN. However, the manual delineation of kidney vascular system and tumor on each…
Ultrafiltration membrane modules suffer from a permeate flow decrease arising during filtration and caused by concentration polarization and fouling in, e.g., fermentation broth purification. Such performance losses are frequently mitigated…
High throughput screening of small molecules and natural products is costly, requiring significant amounts of time, reagents, and operating space. Although microarrays have proven effective in the miniaturization of screening for certain…
We have developed several distinct model systems of microtubule-based 3D active isotropic fluids and have compared their dynamical and structural properties. The non-equilibrium dynamics of these fluids is powered by three different types…
Deep generative models have shown success in generating 3D shapes with different representations. In this work, we propose Neural Volumetric Mesh Generator(NVMG) which can generate novel and high-quality volumetric meshes. Unlike the…
Recent developments in lipid membrane models for simulations are reviewed. To reduce computational costs, various coarse-grained molecular models have been proposed. Among them, implicit solvent (solvent-free) molecular models are…
In the emerging field of molecular communication (MC), testbeds are needed to validate theoretical concepts, motivate applications, and guide further modeling efforts. To this end, this paper presents a flexible and extendable in-vessel…
Realistic and parameterized 3D models of human anatomy have become invaluable in research, diagnostics, and surgical planning. However, the development of detailed models for internal organs, such as the stomach, has been limited by data…
In this study, we present a comprehensive exploration of formation of different phases in lipid molecules using a coarse-grained implicit solvent model, where each lipid molecule is represented as a rigid, three-bead rod-like structure. Our…
Recent advance in nanotechnology has led to rapid advances in nanofluidics, which has been established as a reliable means for a wide variety of applications, including molecular separation, detection, crystallization and biosynthesis.…
Renal cancer is one of the most prevalent cancers worldwide. Clinical signs of kidney cancer include hematuria and low back discomfort, which are quite distressing to the patient. Some surgery-based renal cancer treatments like laparoscopic…
We present a simple coarse-grained bead-and-spring model for lipid bilayers. The system has been developed to reproduce the main (gel-liquid) transition of biological membranes on intermediate length scales of a couple of nanometres and is…