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Human behaviour strongly influences the spread of infectious diseases: understanding the interplay between epidemic dynamics and adaptive behaviours is essential to improve response strategies to epidemics, with the goal of containing the…

Physics and Society · Physics 2024-08-21 Marco Mancastroppa , Alessandro Vezzani , Vittoria Colizza , Raffaella Burioni

Infectious disease modeling is used to forecast epidemics and assess the effectiveness of intervention strategies. Although the core assumption of mass-action models of homogeneously mixed population is often implausible, they are…

Physics and Society · Physics 2024-08-29 Thien-Minh Le , Jukka-Pekka Onnela

Despite the advanced stage of epidemic modeling, there is a major demand for methods to incorporate behavioral responses to the spread of a disease such as social distancing and adoption of prevention methods. Mobility plays an important…

Physics and Society · Physics 2022-03-14 Paulo Cesar Ventura , Alberto Aleta , Francisco A. Rodrigues , Yamir Moreno

Dynamics on networks is considered from the perspective of Markov stochastic processes. We partially describe the state of the system through network motifs and infer any missing data using the available information. This versatile approach…

We study the problem of estimating the origin of an epidemic outbreak -- given a contact network and a snapshot of epidemic spread at a certain time, determine the infection source. Finding the source is important in different contexts of…

Physics and Society · Physics 2014-11-20 Andrey Y. Lokhov , Marc Mézard , Hiroki Ohta , Lenka Zdeborová

Understanding how epidemics spread in a system is a crucial step to prevent and control outbreaks, with broad implications on the system's functioning, health, and associated costs. This can be achieved by identifying the elements at higher…

Physics and Society · Physics 2015-03-16 Eugenio Valdano , Chiara Poletto , Armando Giovannini , Diana Palma , Lara Savini , Vittoria Colizza

Motivated by the increasing number of COVID-19 cases that have been observed in many countries after the vaccination and relaxation of non-pharmaceutical interventions, we propose a mathematical model on time-varying networks for the spread…

Dynamical Systems · Mathematics 2022-03-09 Kathinka Frieswijk , Lorenzo Zino , Ming Cao

The emergence of novel infectious agents presents challenges to statistical models of disease transmission. These challenges arise from limited, poor-quality data and an incomplete understanding of the agent. Moreover, outbreaks manifest…

Methodology · Statistics 2024-03-20 Jiasheng Shi , Jeffrey S. Morris , David M. Rubin , Jing Huang

We study spreading on networks where the contact dynamics between the nodes is governed by a random process and where the inter-contact time distribution may differ from the exponential. We consider a process of imperfect spreading, where…

Physics and Society · Physics 2016-07-07 Martin Gueuning , Jean-Charles Delvenne , Renaud Lambiotte

We study the relative importance of two key control measures for epidemic spreading: endogenous social self-distancing and exogenous imposed quarantine. We use the framework of adaptive networks, moment-closure, and ordinary differential…

Populations and Evolution · Quantitative Biology 2020-10-22 Leonhard Horstmeyer , Christian Kuehn , Stefan Thurner

To better predict the dynamics of epidemics such as COVID-19, it is important not only to investigate the network of local and long-range contagious contacts but also to understand the temporal dynamics of infectiousness and detectable…

Populations and Evolution · Quantitative Biology 2025-09-03 Miguel A. Cajahuanca Ricaldi , Yaroslav Ispolatov

The design of an efficient curing policy, able to stem an epidemic process at an affordable cost, has to account for the structure of the population contact network supporting the contagious process. Thus, we tackle the problem of…

Optimization and Control · Mathematics 2017-12-04 Stefania Ottaviano , Francesco De Pellegrini , Stefano Bonaccorsi , Piet Van Mieghem

The COVID-19 crisis highlighted the importance of non-medical interventions, such as testing and isolation of infected individuals, in the control of epidemics. Here, we show how to minimize testing needs while maintaining the number of…

Systems and Control · Electrical Eng. & Systems 2024-07-04 D. Acemoglu , A. Fallah , A. Giometto , D. Huttenlocher , A. Ozdaglar , F. Parise , S. Pattathil

We analyze a recently proposed temporal centrality measure applied to an empirical network based on person-to-person contacts in an emergency department of a busy urban hospital. We show that temporal centrality identifies a distinct set of…

Physics and Society · Physics 2016-03-15 Isabel Chen , Michele Benzi , Howard H. Chang , Vicki S. Hertzberg

The paper presents an algorithm for syndromic surveillance of an epidemic outbreak formulated in the context of stochastic nonlinear filtering. The dynamics of the epidemic is modeled using a generalized compartmental epidemiological model…

Quantitative Methods · Quantitative Biology 2011-10-24 Alex Skvortsov , Branko Ristic

Group testing was conceived during World War II to identify soldiers infected with syphilis using as few tests as possible, and it has attracted renewed interest during the COVID-19 pandemic. A long-standing assumption in the probabilistic…

Social and Information Networks · Computer Science 2022-11-18 Surin Ahn , Wei-Ning Chen , Ayfer Ozgur

Containment of epidemic outbreaks entails great societal and economic costs. Cost-effective containment strategies rely on efficiently identifying infected individuals, making the best possible use of the available testing resources.…

Populations and Evolution · Quantitative Biology 2020-12-01 Laura Natali , Saga Helgadottir , Onofrio M. Marago , Giovanni Volpe

We investigate model assessment and selection in a changing environment, by synthesizing datasets from both the current time period and historical epochs. To tackle unknown and potentially arbitrary temporal distribution shift, we develop…

Machine Learning · Computer Science 2024-06-05 Elise Han , Chengpiao Huang , Kaizheng Wang

Theoretical modeling of computer virus/worm epidemic dynamics is an important problem that has attracted many studies. However, most existing models are adapted from biological epidemic ones. Although biological epidemic models can…

Dynamical Systems · Mathematics 2016-04-08 Shouhuai Xu , Wenlian Lu , Li Xu , Zhenxin Zhan

For many infectious disease outbreaks, the at-risk population changes their behavior in response to the outbreak severity, causing the transmission dynamics to change in real-time. Behavioral change is often ignored in epidemic modeling…

Methodology · Statistics 2023-10-25 Caitlin Ward , Rob Deardon , Alexandra M. Schmidt