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The chorioallantoic membrane (CAM) model is a widely used in vivo platform for studying angiogenesis, especially in relation to tumor growth, drug delivery, and vascular biology.Since the topology and morphology of developing blood vessels…

Image and Video Processing · Electrical Eng. & Systems 2025-09-26 Pengwu Song , Zhiping Wang , Peng Yao , Liang Xu , Shuwei Shen , Pengfei Shao , Mingzhai Sun , Ronald X. Xu

Automated medical image segmentation inherently involves a certain degree of uncertainty. One key factor contributing to this uncertainty is the ambiguity that can arise in determining the boundaries of a target region of interest,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-28 Qingqiao Hu , Hao Wang , Jing Luo , Yunhao Luo , Zhiheng Zhangg , Jan S. Kirschke , Benedikt Wiestler , Bjoern Menze , Jianguo Zhang , Hongwei Bran Li

A novel algorithm is proposed for segmenting an image into multiple levels using its mean and variance. Starting from the extreme pixel values at both ends of the histogram plot, the algorithm is applied recursively on sub-ranges computed…

Computer Vision and Pattern Recognition · Computer Science 2007-05-23 Siddharth Arora , Jayadev Acharya , Amit Verma , Prasanta K. Panigrahi

The availability of real-world datasets is the prerequisite for developing object detection methods for autonomous driving. While ambiguity exists in object labels due to error-prone annotation process or sensor observation noises, current…

Computer Vision and Pattern Recognition · Computer Science 2020-08-04 Zining Wang , Di Feng , Yiyang Zhou , Lars Rosenbaum , Fabian Timm , Klaus Dietmayer , Masayoshi Tomizuka , Wei Zhan

On the medical images, many of the tissues/lesions may be ambiguous. That is why the medical segmentation is typically annotated by a group of clinical experts to mitigate the personal bias. However, this clinical routine also brings new…

Image and Video Processing · Electrical Eng. & Systems 2022-08-08 Junde Wu , Huihui Fang , Hoayi Xiong , Lixin Duan , Mingkui Tan , Weihua Yang , Huiying Liu , Yanwu Xu

Although supervised deep-learning has achieved promising performance in medical image segmentation, many methods cannot generalize well on unseen data, limiting their real-world applicability. To address this problem, we propose a deep…

Image and Video Processing · Electrical Eng. & Systems 2022-06-10 Shangqi Gao , Hangqi Zhou , Yibo Gao , Xiahai Zhuang

The ideal observer (IO) sets an upper performance limit among all observers and has been advocated for assessing and optimizing imaging systems. For general joint detection and estimation (detection-estimation) tasks, estimation ROC (EROC)…

Signal Processing · Electrical Eng. & Systems 2021-12-03 Kaiyan Li , Weimin Zhou , Hua Li , Mark A. Anastasio

Two forms of imbalances are commonly observed in point cloud semantic segmentation datasets: (1) category imbalances, where certain objects are more prevalent than others; and (2) size imbalances, where certain objects occupy more points…

Computer Vision and Pattern Recognition · Computer Science 2024-08-01 Zhuheng Lu , Ting Wu , Yuewei Dai , Weiqing Li , Zhiyong Su

Despite significant advancements, segmentation based on deep neural networks in medical and surgical imaging faces several challenges, two of which we aim to address in this work. First, acquiring complete pixel-level segmentation labels…

Computer Vision and Pattern Recognition · Computer Science 2026-04-09 Junwen Wang , Zhonghao Wang , Oscar MacCormac , Jonathan Shapey , Tom Vercauteren

In medical imaging, the heterogeneity of multi-centre data impedes the applicability of deep learning-based methods and results in significant performance degradation when applying models in an unseen data domain, e.g. a new centreor a new…

Computer Vision and Pattern Recognition · Computer Science 2020-08-12 Hongwei Li , Timo Loehr , Anjany Sekuboyina , Jianguo Zhang , Benedikt Wiestler , Bjoern Menze

Medical image segmentation methods generally assume that the process from medical image to segmentation is unbiased, and use neural networks to establish conditional probability models to complete the segmentation task. This assumption does…

Image and Video Processing · Electrical Eng. & Systems 2025-05-29 Ruiguo Yu , Yiyang Zhang , Yuan Tian , Yujie Diao , Di Jin , Witold Pedrycz

Image segmentation is the process of partitioning the image into significant regions easier to analyze. Nowadays, segmentation has become a necessity in many practical medical imaging methods as locating tumors and diseases. Hidden Markov…

Computer Vision and Pattern Recognition · Computer Science 2018-03-14 EL-Hachemi Guerrout , Samy Ait-Aoudia , Dominique Michelucci , Ramdane Mahiou

Medical artificial intelligence (AI) systems, particularly multimodal vision-language models (VLM), often exhibit intersectional biases where models are systematically less confident in diagnosing marginalised patient subgroups. Such bias…

Computer Vision and Pattern Recognition · Computer Science 2025-12-25 Yupeng Zhang , Adam G. Dunn , Usman Naseem , Jinman Kim

We focus on the construction of a loss function for the bounding box regression. The Intersection over Union (IoU) metric is improved to converge faster, to make the surface of the loss function smooth and continuous over the whole searched…

Computer Vision and Pattern Recognition · Computer Science 2023-03-29 Petra Števuliáková , Petr Hurtik

Optimal margin Distribution Machine (ODM) is a newly proposed statistical learning framework rooting in the novel margin theory, which demonstrates better generalization performance than the traditional large margin based counterparts.…

Machine Learning · Computer Science 2023-06-13 Yilin Wang , Nan Cao , Teng Zhang , Xuanhua Shi , Hai Jin

Learning a medical image segmentation model is an inherently ambiguous task, as uncertainties exist in both images (noise) and manual annotations (human errors and bias) used for model training. To build a trustworthy image segmentation…

Image and Video Processing · Electrical Eng. & Systems 2023-08-17 Xinyu Bai , Wenjia Bai

Biomedical image segmentation is critical for accurate identification and analysis of anatomical structures in medical imaging, particularly in cardiac MRI. Manual segmentation is labor-intensive, time-consuming, and prone to errors,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-28 Ting Yu Tsai , Li Lin , Shu Hu , Ming-Ching Chang , Hongtu Zhu , Xin Wang

Background: In the field of radiology and radiotherapy, accurate delineation of tissues and organs plays a crucial role in both diagnostics and therapeutics. While the gold standard remains expert-driven manual segmentation, many automatic…

Quantitative Methods · Quantitative Biology 2025-08-14 Szuzina Fazekas , Bettina Katalin Budai , Viktor Bérczi , Pál Maurovich-Horvat , Zsolt Vizi

Remote sensing image segmentation is a specific task of remote sensing image interpretation. A good remote sensing image segmentation algorithm can provide guidance for environmental protection, agricultural production, and urban…

Computer Vision and Pattern Recognition · Computer Science 2024-01-18 Jiacheng Li

Image segmentation is a critical step in computational biomedical image analysis, typically evaluated using metrics like the Dice coefficient during training and validation. However, in clinical settings without manual annotations,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Sikha O K , Meritxell Riera-Marín , Adrian Galdran , Javier García Lopez , Julia Rodríguez-Comas , Gemma Piella , Miguel A. González Ballester
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