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Source localization based on electroencephalography (EEG) has become a widely used neuroimagining technique. However its precision has been shown to be very dependent on how accurately the brain, head and scalp can be electrically modeled…

Medical Physics · Physics 2020-04-22 Lyes Rahmouni , Adrien Merlini , Axelle Pillain , Francesco P. Andriulli

Source analysis of Electroencephalography (EEG) data requires the computation of the scalp potential induced by current sources in the brain. This so-called EEG forward problem is based on an accurate estimation of the volume conduction…

The surface Boundary Element Method (BEM) is one of the most commonly employed formulations to solve the forward problem in electroencephalography, but the applicability of its classical incarnations is lamentably limited to piece-wise…

Image and Video Processing · Electrical Eng. & Systems 2020-04-27 Maxime Y. Monin , Lyes Rahmouni , Francesco P. Andriulli

The quality of the inverse approach in electroencephalography (EEG) source analysis is - among other things - depending on the accuracy of the forward modeling approach, i.e., the simulation of the electric potential for a known dipole…

Medical Physics · Physics 2022-08-08 Florian Drechsler , Johannes Vorwerk , Jens Haueisen , Lars Grasedyck , Carsten H. Wolters

Solving the electroencephalography (EEG) forward problem is a fundamental step in a wide range of applications including biomedical imaging techniques based on inverse source localization. State-of-the-art electromagnetic solvers resort to…

Computational Physics · Physics 2020-04-22 Maxime Y. Monin , Lyes Rahmouni , Adrien Merlini , Francesco P. Andriulli

Electroencephalography (EEG) source imaging aims to infer brain activity from electrical potentials measured on the scalp. This is a difficult problem because many different source patterns can explain the same measurements. The result…

Numerical Analysis · Mathematics 2026-04-29 Santtu Söderholm , Joonas Lahtinen , Sampsa Pursiainen

The electroencephalography (EEG) forward problem, the computation of the electric potential generated by a known electric current source configuration in the brain, is a key step of EEG source analysis. In this problem, it is often desired…

Medical Physics · Physics 2019-03-28 Axelle Pillain , Lyes Rahmouni , Francesco Andriulli

Current non-invasive neuroimaging techniques trade off between spatial resolution and temporal resolution. While magnetoencephalography (MEG) can capture rapid neural dynamics and functional magnetic resonance imaging (fMRI) can spatially…

Neurons and Cognition · Quantitative Biology 2025-10-13 Beige Jerry Jin , Leila Wehbe

This study introduces a novel integration of the Brainstorm (BST) software and the Zeffiro Interface (ZI) to enable whole-head, multi-compartment volume conductor modeling for electroencephalography (EEG) source imaging, with a particular…

Electrocorticography (ECoG) or intracranial electroencephalography (iEEG) monitors electric potential directly on the surface of the brain and can be used to inform treatment planning for epilepsy surgery when paired with numerical…

Finite element methods have been shown to achieve high accuracies in numerically solving the EEG forward problem and they enable the realistic modeling of complex geometries and important conductive features such as anisotropic…

Numerical Analysis · Mathematics 2017-08-25 Johannes Vorwerk , Christian Engwer , Sampsa Pursiainen , Carsten H. Wolters

Accurately monitoring cognitive load in real time is critical for Brain-Computer Interfaces (BCIs) that adapt to user engagement and support personalized learning. Electroencephalography (EEG) offers a non-invasive, cost-effective modality…

Human-Computer Interaction · Computer Science 2026-05-04 Deeksha M. Shama , Dimitra Emmanouilidou , Ivan J. Tashev

Magnetoencephalography (MEG) provides dynamic spatial-temporal insight of neural activities in the cortex. Because the number of possible sources is far greater than the number of MEG detectors, the proposition to localize sources directly…

Quantitative Methods · Quantitative Biology 2009-03-06 Hung-I Pai , Chih-Yuan Tseng , H. C. Lee

Electroencephalography (EEG) is a non-invasive technique for recording brain electrical activity, widely used in brain-computer interface (BCI) and healthcare. Recent EEG foundation models trained on large-scale datasets have shown improved…

Machine Learning · Computer Science 2025-09-29 Yi Ding , Muyun Jiang , Weibang Jiang , Shuailei Zhang , Xinliang Zhou , Chenyu Liu , Shanglin Li , Yong Li , Cuntai Guan

The goal of this study is to develop focal, accurate and robust finite element method (FEM) based approaches which can predict the electric potential on the surface of the computational domain given its structure and internal primary source…

Medical Physics · Physics 2016-12-21 Sampsa Pursiainen , Johannes Vorwerk , Carsten H. Wolters

We present a fully modular and scalable software pipeline for processing electron microscope (EM) images of brain slices into 3D visualization of individual neurons and demonstrate an end-to-end segmentation of a large EM volume using a…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-11-20 Rafael Vescovi , Hanyu Li , Jeffery Kinnison , Murat Keceli , Misha Salim , Narayanan Kasthuri , Thomas D. Uram , Nicola Ferrier

Mental disorders present challenges in diagnosis and treatment due to their complex and heterogeneous nature. Electroencephalogram (EEG) has shown promise as a potential biomarker for these disorders. However, existing methods for analyzing…

Methodology · Statistics 2024-01-30 Xingche Guo , Bin Yang , Ji Meng Loh , Qinxia Wang , Yuanjia Wang

Electroencephalography (EEG) and magnetoencephalography (MEG) measure neural activity non-invasively by capturing electromagnetic fields generated by dendritic currents. Although rooted in the same biophysics, EEG and MEG exhibit distinct…

Signal Processing · Electrical Eng. & Systems 2025-10-16 Qinfan Xiao , Ziyun Cui , Chi Zhang , Siqi Chen , Wen Wu , Andrew Thwaites , Alexandra Woolgar , Bowen Zhou , Chao Zhang

In this paper we present a new discretization strategy for the boundary element formulation of the Electroencephalography (EEG) forward problem. Boundary integral formulations, classically solved with the Boundary Element Method (BEM), are…

Medical Physics · Physics 2016-03-22 Lyes Rahmouni , Simon Adrian , Kristof Cools , Francesco P. Andriulli

Inter subject variability of the electrical conductivity of brain, skull and skin strongly limits the accuracy by which current sources underlying electro-encephalography (EEG) can be localized in the brain. This inter subject variability…

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