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Deep learning based approaches to Computer Aided Diagnosis (CAD) typically pose the problem as an image classification (Normal or Abnormal) problem. These systems achieve high to very high accuracy in specific disease detection for which…
Neuroblastoma is one of the most common cancers in infants, and the initial diagnosis of this disease is difficult. At present, the MYCN gene amplification (MNA) status is detected by invasive pathological examination of tumor samples. This…
Early detection of cancerous tissue is crucial for long-term patient survival. In the head and neck region, a typical diagnostic procedure is an endoscopic intervention where a medical expert manually assesses tissue using RGB camera…
Deep learning has emerged as a powerful artificial intelligence tool to interpret medical images for a growing variety of applications. However, the paucity of medical imaging data with high-quality annotations that is necessary for…
Tumor-stroma ratio (TSR) is a prognostic factor for many types of solid tumors. In this study, we propose a method for automated estimation of TSR from histopathological images of colorectal cancer. The method is based on convolutional…
Algorithmic image-based diagnosis and prognosis of neurodegenerative diseases on longitudinal data has drawn great interest from computer vision researchers. The current state-of-the-art models for many image classification tasks are based…
The brain tumor is the most aggressive kind of tumor and can cause low life expectancy if diagnosed at the later stages. Manual identification of brain tumors is tedious and prone to errors. Misdiagnosis can lead to false treatment and thus…
The most deadly and life-threatening disease in the world is lung cancer. Though early diagnosis and accurate treatment are necessary for lowering the lung cancer mortality rate. A computerized tomography (CT) scan-based image is one of the…
Foundation models pretrained on large-scale pathology datasets have shown promising results across various diagnostic tasks. Here, we present a systematic evaluation of transfer learning strategies for brain tumor classification using these…
Bone marrow cytology is required to make a hematological diagnosis, influencing critical clinical decision points in hematology. However, bone marrow cytology is tedious, limited to experienced reference centers and associated with high…
Lung and Colon cancer are one of the leading causes of mortality and morbidity in adults. Histopathological diagnosis is one of the key components to discern cancer type. The aim of the present research is to propose a computer aided…
Breast cancer is the most common invasive cancer in women, and the second main cause of death. Breast cancer screening is an efficient method to detect indeterminate breast lesions early. The common approaches of screening for women are…
Melanoma is a type of skin cancer with the most rapidly increasing incidence. Early detection of melanoma using dermoscopy images significantly increases patients' survival rate. However, accurately classifying skin lesions by eye,…
Colorectal and prostate cancers are the most common types of cancer in men worldwide. To diagnose colorectal and prostate cancer, a pathologist performs a histological analysis on needle biopsy samples. This manual process is time-consuming…
Breast cancer has the highest incidence and second highest mortality rate for women in the US. Our study aims to utilize deep learning for benign/malignant classification of mammogram tumors using a subset of cases from the Digital Database…
In practice, histopathological diagnosis of tumor malignancy often requires a human expert to scan through histopathological images at multiple magnification levels, after which a final diagnosis can be accurately determined. However,…
Segmentation of histological images is one of the most crucial tasks for many biomedical analyses including quantification of certain tissue type. However, challenges are posed by high variability and complexity of structural features in…
Ovarian cancer remains a challenging malignancy to diagnose and manage, with prognosis heavily dependent on the stage at detection. Accurate grading and staging, primarily based on histopathological examination of biopsy tissue samples, are…
As one kind of skin cancer, melanoma is very dangerous. Dermoscopy based early detection and recarbonization strategy is critical for melanoma therapy. However, well-trained dermatologists dominant the diagnostic accuracy. In order to solve…
Endometrial cancer, the fourth most common cancer in females in the United States, with the lifetime risk for developing this disease is approximately 2.8% in women. Precise histologic evaluation and molecular classification of endometrial…