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We present the preliminary high-level design and features of DynamicPPL.jl, a modular library providing a lightning-fast infrastructure for probabilistic programming. Besides a computational performance that is often close to or better than…

Machine Learning · Computer Science 2020-02-10 Mohamed Tarek , Kai Xu , Martin Trapp , Hong Ge , Zoubin Ghahramani

Existing open-source modeling frameworks dedicated to energy systems optimization typically utilize (mixed-integer) linear programming ((MI)LP) formulations, which lack modeling freedom for technical system design and operation. We present…

PACKMOL is a widely utilized molecular modeling tool within the computational chemistry community. However, its perceivable advantages have been impeded by the long-standing lack of a robust open-source graphical user interface (GUI) that…

Chemical Physics · Physics 2024-08-26 Jian Huang , Chenchen Wu , Xiner Yang , Zaixing Yang , Shengtang Liu , Gang Yu

With recent increasing computational and data requirements of scientific applications, the use of large clustered systems as well as distributed resources is inevitable. Although executing large applications in these environments brings…

Distributed, Parallel, and Cluster Computing · Computer Science 2011-06-30 Alexandru Costan , Florin Pop , Corina Stratan , Ciprian Dobre , Catalin Leordeanu , Valentin Cristea

In the field of microservices, Model-Driven Engineering has emerged as a powerful methodology for architectural design, and new programming languages have introduced language abstractions to deal with microservice development more…

Software Engineering · Computer Science 2021-04-07 Saverio Giallorenzo , Fabrizio Montesi , Marco Peressotti , Florian Rademacher , Sabine Sachweh

Technical computing is a challenging application area for programming languages to address. This is evinced by the unusually large number of specialized languages in the area (e.g. MATLAB, R), and the complexity of common software stacks,…

Programming Languages · Computer Science 2018-08-13 Jeff Bezanson , Jake Bolewski , Jiahao Chen

We present BSeries.jl, a Julia package for the computation and manipulation of B-series, which are a versatile theoretical tool for understanding and designing discretizations of differential equations. We give a short introduction to the…

Numerical Analysis · Mathematics 2022-12-06 David I. Ketcheson , Hendrik Ranocha

Dynamical systems are ubiquitous in science and engineering as models of phenomena that evolve over time. Although complex dynamical systems tend to have important modular structure, conventional modeling approaches suppress this structure.…

Category Theory · Mathematics 2022-11-04 Sophie Libkind , Andrew Baas , Evan Patterson , James Fairbanks

Databricks job orchestration systems (e.g., LeJOT) reduce cloud costs by selecting low-priced compute configurations while meeting latency and dependency constraints. Accurate execution-time prediction under heterogeneous instance types and…

Machine Learning · Computer Science 2026-03-10 Lizhi Ma , Yi-Xiang Hu , Yihui Ren , Feng Wu , Xiang-Yang Li

Automated machine learning (AutoML) accelerates AI development by automating tasks in the development pipeline, such as optimal model search and hyperparameter tuning. Existing AutoML systems often require technical expertise to set up…

Machine Learning · Computer Science 2025-06-09 Patara Trirat , Wonyong Jeong , Sung Ju Hwang

Any-to-any multimodal models that jointly handle text, images, video, and audio represent a significant advance in multimodal AI. However, their complex architectures (typically combining multiple autoregressive LLMs, diffusion…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-03 Peiqi Yin , Jiangyun Zhu , Han Gao , Chenguang Zheng , Yongxiang Huang , Taichang Zhou , Ruirui Yang , Weizhi Liu , Weiqing Chen , Canlin Guo , Didan Deng , Zifeng Mo , Cong Wang , James Cheng , Roger Wang , Hongsheng Liu

Increasing emphasis on data and quantitative methods in the biomedical sciences is making biological research more computational. Collecting, curating, processing, and analysing large genomic and imaging data sets poses major computational…

Quantitative Methods · Quantitative Biology 2021-09-22 Elisabeth Roesch , Joe G. Greener , Adam L. MacLean , Huda Nassar , Christopher Rackauckas , Timothy E. Holy , Michael P. H. Stumpf

Nonlinear mixed effects modeling is a powerful tool when analyzing data from several entities in an experiment. In this paper, we present NLMEModeling, a package for mixed effects modeling in Wolfram Mathematica. NLMEModeling supports mixed…

Computation · Statistics 2020-11-16 Jacob Leander , Joachim Almquist , Anna Johnning , Julia Larsson , Mats Jirstrand

We present HYMOR (HYpersonic MOdal/non-modal, and Receptivity), an open-source computational framework for the linear stability analysis of high-enthalpy hypersonic flows. The toolkit includes MATLAB and Julia implementations and is…

Fluid Dynamics · Physics 2026-04-07 Adrián Antón-Álvarez , Adrián Lozano-Durán

Prompt optimization has become crucial for enhancing the performance of large language models (LLMs) across a broad range of tasks. Although many research papers demonstrate its effectiveness, practical adoption is hindered because existing…

Computation and Language · Computer Science 2026-02-24 Tom Zehle , Timo Heiß , Moritz Schlager , Matthias Aßenmacher , Matthias Feurer

Computing systems are consuming an increasing and unsustainable fraction of society's energy footprint, notably in data centers. Meanwhile, energy-efficient software engineering techniques are often absent from undergraduate curricula. We…

Frank-Wolfe (FW) algorithms have emerged as an essential class of methods for constrained optimization, especially on large-scale problems. In this paper, we summarize the algorithmic design choices and progress made in the last years of…

Large language models (LLMs) are transforming electronic design automation (EDA) by enhancing design stages such as schematic design, simulation, netlist synthesis, and place-and-route. Existing methods primarily focus these optimisations…

Predicting the degradation processes of molecules over long timescales is a key aspect of industrial materials design. However, it is made computationally challenging by the need to construct large networks of chemical reactions that are…

Chemical Physics · Physics 2025-05-02 Joe Gilkes , Mark Storr , Reinhard J. Maurer , Scott Habershon

Current direct-collocation-based optimal control software is either easy to use or fast, but not both. This is a major limitation for users that are trying to formulate complex optimal control problems (OCPs) for use in on-line…

Mathematical Software · Computer Science 2020-05-05 Huckleberry Febbo , Paramsothy Jayakumar , Jeffrey L. Stein , Tulga Ersal