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Histopathology image analysis plays a critical role in cancer diagnosis and treatment. To automatically segment the cancerous regions, fully supervised segmentation algorithms require labor-intensive and time-consuming labeling at the pixel…

Image and Video Processing · Electrical Eng. & Systems 2019-08-29 Gang Xu , Zhigang Song , Zhuo Sun , Calvin Ku , Zhe Yang , Cancheng Liu , Shuhao Wang , Jianpeng Ma , Wei Xu

Curating large-scale fully annotated datasets is expensive, laborious, and cumbersome, especially for medical images. Several methods have been proposed in the literature that make use of weak annotations in the form of scribbles. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Ke Zhang , Vishal M. Patel

Fine-grained Vision-Language Pre-training (FVLP) demonstrates significant potential in 3D medical image understanding by aligning anatomy-level visual representations with corresponding textual descriptions. However, existing FVLP paradigms…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Hanwen Zhang , Yao Liu , Die Dai , Jiaye Yang , Qiao Liu , Yutong Xie , Peng Wang

Supervised object detection and semantic segmentation require object or even pixel level annotations. When there exist image level labels only, it is challenging for weakly supervised algorithms to achieve accurate predictions. The accuracy…

Computer Vision and Pattern Recognition · Computer Science 2018-03-06 Weifeng Ge , Sibei Yang , Yizhou Yu

Semi-supervised learning for medical image segmentation is an important area of research for alleviating the huge cost associated with the construction of reliable large-scale annotations in the medical domain. Recent semi-supervised…

Computer Vision and Pattern Recognition · Computer Science 2022-05-17 Chae Eun Lee , Hyelim Park , Yeong-Gil Shin , Minyoung Chung

In the last few years, deep learning classifiers have shown promising results in image-based medical diagnosis. However, interpreting the outputs of these models remains a challenge. In cancer diagnosis, interpretability can be achieved by…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Kangning Liu , Yiqiu Shen , Nan Wu , Jakub Chłędowski , Carlos Fernandez-Granda , Krzysztof J. Geras

We propose adversarial constrained-CNN loss, a new paradigm of constrained-CNN loss methods, for weakly supervised medical image segmentation. In the new paradigm, prior knowledge is encoded and depicted by reference masks, and is further…

Computer Vision and Pattern Recognition · Computer Science 2020-05-04 Pengyi Zhang , Yunxin Zhong , Xiaoqiong Li

We propose a novel algorithm for weakly supervised semantic segmentation based on image-level class labels only. In weakly supervised setting, it is commonly observed that trained model overly focuses on discriminative parts rather than the…

Computer Vision and Pattern Recognition · Computer Science 2018-01-09 Seunghoon Hong , Donghun Yeo , Suha Kwak , Honglak Lee , Bohyung Han

Segmentation is one of the most important tasks in the medical imaging pipeline as it influences a number of image-based decisions. To be effective, fully supervised segmentation approaches require large amounts of manually annotated…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Tyler Ward , Aaron Moseley , Abdullah-Al-Zubaer Imran

Nuclei instance segmentation on histopathology images is of great clinical value for disease analysis. Generally, fully-supervised algorithms for this task require pixel-wise manual annotations, which is especially time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Yang Zhou , Yongjian Wu , Zihua Wang , Bingzheng Wei , Maode Lai , Jianzhong Shou , Yubo Fan , Yan Xu

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha

Universal models for medical image segmentation, such as interactive and in-context learning (ICL) models, offer strong generalization but require extensive annotations. Interactive models need repeated user prompts for each image, while…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Jiesi Hu , Yanwu Yang , Zhiyu Ye , Jinyan Zhou , Jianfeng Cao , Hanyang Peng , Ting Ma

In weakly supervised medical image segmentation, the absence of structural priors and the discreteness of class feature distribution present a challenge, i.e., how to accurately propagate supervision signals from local to global regions…

Computer Vision and Pattern Recognition · Computer Science 2024-05-21 Yu Lei , Haolun Luo , Lituan Wang , Zhenwei Zhang , Lei Zhang

Medical image segmentation is critical for computer-aided diagnosis. However, dense pixel-level annotation is time-consuming and expensive, and medical datasets often exhibit severe class imbalance. Such imbalance causes minority structures…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Yingxue Su , Yiheng Zhong , Keying Zhu , Zimu Zhang , Zhuoru Zhang , Yifang Wang , Yuxin Zhang , Jingxin Liu

Although existing semantic segmentation approaches achieve impressive results, they still struggle to update their models incrementally as new categories are uncovered. Furthermore, pixel-by-pixel annotations are expensive and…

Computer Vision and Pattern Recognition · Computer Science 2022-04-04 Fabio Cermelli , Dario Fontanel , Antonio Tavera , Marco Ciccone , Barbara Caputo

In this paper, we study weakly-supervised laparoscopic image segmentation with sparse annotations. We introduce a novel Bayesian deep learning approach designed to enhance both the accuracy and interpretability of the model's segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-14 Zhou Zheng , Yuichiro Hayashi , Masahiro Oda , Takayuki Kitasaka , Kensaku Mori

In this paper, we develop a new weakly-supervised learning algorithm to learn to segment cancerous regions in histopathology images. Our work is under a multiple instance learning framework (MIL) with a new formulation, deep weak…

Computer Vision and Pattern Recognition · Computer Science 2017-08-30 Zhipeng Jia , Xingyi Huang , Eric I-Chao Chang , Yan Xu

Most of the existing semantic segmentation approaches with image-level class labels as supervision, highly rely on the initial class activation map (CAM) generated from the standard classification network. In this paper, a novel…

Computer Vision and Pattern Recognition · Computer Science 2022-09-19 Jinlong Li , Zequn Jie , Xu Wang , Yu Zhou , Xiaolin Wei , Lin Ma

Weakly supervised segmentation requires assigning a label to every pixel based on training instances with partial annotations such as image-level tags, object bounding boxes, labeled points and scribbles. This task is challenging, as coarse…

Computer Vision and Pattern Recognition · Computer Science 2021-05-12 Tsung-Wei Ke , Jyh-Jing Hwang , Stella X. Yu

We propose and study a realistic Continual Learning (CL) setting where learning algorithms are granted a restricted computational budget per time step while training. We apply this setting to large-scale semi-supervised Continual Learning…

Machine Learning · Computer Science 2024-06-11 Wenxuan Zhang , Youssef Mohamed , Bernard Ghanem , Philip H. S. Torr , Adel Bibi , Mohamed Elhoseiny
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