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Light-field microscopy (LFM) enables rapid volumetric imaging through single-frame acquisition and fast 3D reconstruction algorithms. The high speed and low phototoxicity of LFM make it highly suitable for real-time 3D fluorescence imaging,…

Optics · Physics 2025-02-24 Bohan Qu , Zhouyu Jin , You Zhou , Bo Xiong , Xun Cao

Automated histopathological image analysis offers exciting opportunities for the early diagnosis of several medical conditions including cancer. There are however stiff practical challenges: 1.) discriminative features from such images for…

Image and Video Processing · Electrical Eng. & Systems 2017-12-25 Xuelu Li , Vishal Monga , U. K. Arvind Rao

Accurate lumbar spine segmentation is crucial for diagnosing spinal disorders. Existing methods typically use coarse-grained segmentation strategies that lack the fine detail needed for precise diagnosis. Additionally, their reliance on…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Sheng Lian , Jianlong Cai , Dengfeng Pan , Guang-Yong Chen , Hao Xu , Fan Zhang , Guodong Fan , Shuo Li

Breast ultrasound (US) is an effective imaging modality for breast cancer detection and diagnosis. US computer-aided diagnosis (CAD) systems have been developed for decades and have employed either conventional hand-crafted features or…

Medical Physics · Physics 2020-03-12 Erlei Zhang , Stephen Seiler , Mingli Chen , Weiguo Lu , Xuejun Gu

The healthcare domain is characterized by heterogeneous data modalities, such as imaging and physiological data. In practice, the variety of medical data assists clinicians in decision-making. However, most of the current state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Nasir Hayat , Krzysztof J. Geras , Farah E. Shamout

Deep learning methods, and in particular convolutional neural networks (CNNs), have led to an enormous breakthrough in a wide range of computer vision tasks, primarily by using large-scale annotated datasets. However, obtaining such…

Computer Vision and Pattern Recognition · Computer Science 2019-01-23 Maayan Frid-Adar , Idit Diamant , Eyal Klang , Michal Amitai , Jacob Goldberger , Hayit Greenspan

Breast cancer is a major concern for women's health globally, with axillary lymph node (ALN) metastasis identification being critical for prognosis evaluation and treatment guidance. This paper presents a deep learning (DL) classification…

Image and Video Processing · Electrical Eng. & Systems 2023-10-09 Glejdis Shkëmbi , Johanna P. Müller , Zhe Li , Katharina Breininger , Peter Schüffler , Bernhard Kainz

Machine Learning (ML) is widely used to automatically extract meaningful information from Electronic Health Records (EHR) to support operational, clinical, and financial decision-making. However, ML models require a large number of…

Machine Learning · Computer Science 2021-04-14 Martha Dais Ferreira , Michal Malyska , Nicola Sahar , Riccardo Miotto , Fernando Paulovich , Evangelos Milios

Throughout the world, breast cancer is one of the leading causes of female death. Recently, deep learning methods are developed to automatically grade breast cancer of histological slides. However, the performance of existing deep learning…

Computer Vision and Pattern Recognition · Computer Science 2022-03-09 Yanyuet Man , Xiangyun Ding , Xingcheng Yao , Han Bao

Active learning (AL) has found wide applications in medical image segmentation, aiming to alleviate the annotation workload and enhance performance. Conventional uncertainty-based AL methods, such as entropy and Bayesian, often rely on an…

Computer Vision and Pattern Recognition · Computer Science 2024-01-30 Siteng Ma , Haochang Wu , Aonghus Lawlor , Ruihai Dong

Multi-modal medical image fusion is essential for the precise clinical diagnosis and surgical navigation since it can merge the complementary information in multi-modalities into a single image. The quality of the fused image depends on the…

Computer Vision and Pattern Recognition · Computer Science 2023-10-25 Xianming Gu , Lihui Wang , Zeyu Deng , Ying Cao , Xingyu Huang , Yue-min Zhu

Active learning (AL) techniques reduce labeling costs for training neural machine translation (NMT) models by selecting smaller representative subsets from unlabeled data for annotation. Diversity sampling techniques select heterogeneous…

Computation and Language · Computer Science 2024-12-19 Abdul Hameed Azeemi , Ihsan Ayyub Qazi , Agha Ali Raza

Machine Learning (ML) is becoming increasingly important in daily life. In this context, Artificial Neural Networks (ANNs) are a popular approach within ML methods to realize an artificial intelligence. Usually, the topology of ANNs is…

Neural and Evolutionary Computing · Computer Science 2022-11-15 Rune Krauss , Marcel Merten , Mirco Bockholt , Rolf Drechsler

Breast cancer screening, primarily conducted through mammography, is often supplemented with ultrasound for women with dense breast tissue. However, existing deep learning models analyze each modality independently, missing opportunities to…

Image and Video Processing · Electrical Eng. & Systems 2023-11-16 Yiqiu Shen , Jungkyu Park , Frank Yeung , Eliana Goldberg , Laura Heacock , Farah Shamout , Krzysztof J. Geras

Current artificial intelligence models for medical imaging are predominantly single modality and single disease. Attempts to create multimodal and multi-disease models have resulted in inconsistent clinical accuracy. Furthermore, training…

Alzheimer's Disease Analysis Model (ADAM) is a multi-agent reasoning large language model (LLM) framework designed to integrate and analyze multimodal data, including microbiome profiles, clinical datasets, and external knowledge bases, to…

Artificial Intelligence · Computer Science 2025-08-22 Ziyuan Huang , Vishaldeep Kaur Sekhon , Roozbeh Sadeghian , Maria L. Vaida , Cynthia Jo , Doyle Ward , Vanni Bucci , John P. Haran

Unsupervised anomaly detection (UAD) presents a complementary alternative to supervised learning for brain tumor segmentation in magnetic resonance imaging (MRI), particularly when annotated datasets are limited, costly, or inconsistent. In…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Gerard Comas-Quiles , Carles Garcia-Cabrera , Julia Dietlmeier , Noel E. O'Connor , Ferran Marques

Accurate segmentation of multiple organs of the head, neck, chest, and abdomen from medical images is an essential step in computer-aided diagnosis, surgical navigation, and radiation therapy. In the past few years, with a data-driven…

Image and Video Processing · Electrical Eng. & Systems 2023-03-03 Xiaoyu Liu , Linhao Qu , Ziyue Xie , Jiayue Zhao , Yonghong Shi , Zhijian Song

Multimodal Machine Learning offers a holistic view of a patient's status, integrating structured and unstructured data from electronic health records (EHR). We propose a framework to predict metastasis risk one month prior to diagnosis,…

Machine Learning · Computer Science 2026-04-01 Franco Rugolon , Korbinian Randl , Braslav Jovanovic , Ioanna Miliou , Panagiotis Papapetrou

In this work, we propose an adversarial attack-based data augmentation method to improve the deep-learning-based segmentation algorithm for the delineation of Organs-At-Risk (OAR) in abdominal Computed Tomography (CT) to facilitate…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Shaoyan Pan , Shao-Yuan Lo , Min Huang , Chaoqiong Ma , Jacob Wynne , Tonghe Wang , Tian Liu , Xiaofeng Yang
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