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Automated segmentation of anatomical sub-regions with high precision has become a necessity to enable the quantification and characterization of cells/ tissues in histology images. Currently, a machine learning model to analyze…

Image and Video Processing · Electrical Eng. & Systems 2023-06-05 Hosein Barzekar , Hai Ngu , Han Hui Lin , Mohsen Hejrati , Steven Ray Valdespino , Sarah Chu , Baris Bingol , Somaye Hashemifar , Soumitra Ghosh

Purpose: The goal of this work was to develop a deep network for whole-head segmentation including clinical MRIs with abnormal anatomy, and compile the first public benchmark dataset for this purpose. We collected 98 MRIs with volumetric…

Image and Video Processing · Electrical Eng. & Systems 2025-09-04 Andrew M Birnbaum , Adam Buchwald , Peter Turkeltaub , Adam Jacks , George Carra , Shreya Kannana , Yu Huang , Abhisheck Datta , Lucas C Parra , Lukas A Hirsch

We propose a novel machine learning strategy for studying neuroanatomical shape variation. Our model works with volumetric binary segmentation images, and requires no pre-processing such as the extraction of surface points or a mesh. The…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Evan M. Yu , Mert R. Sabuncu

Understanding objects in terms of their individual parts is important, because it enables a precise understanding of the objects' geometrical structure, and enhances object recognition when the object is seen in a novel pose or under…

Computer Vision and Pattern Recognition · Computer Science 2020-12-02 Mengqi Guo , Yutong Bai , Zhishuai Zhang , Adam Kortylewski , Alan Yuille

Accurate brain lesion delineation is important for planning neurosurgical treatment. Automatic brain lesion segmentation methods based on convolutional neural networks have demonstrated remarkable performance. However, neural network…

Image and Video Processing · Electrical Eng. & Systems 2024-08-20 Jiayu Huo , Sebastien Ourselin , Rachel Sparks

Segmenting or detecting objects in sparse Lidar point clouds are two important tasks in autonomous driving to allow a vehicle to act safely in its 3D environment. The best performing methods in 3D semantic segmentation or object detection…

Computer Vision and Pattern Recognition · Computer Science 2022-03-31 Corentin Sautier , Gilles Puy , Spyros Gidaris , Alexandre Boulch , Andrei Bursuc , Renaud Marlet

Recent neuroimaging studies that focus on predicting brain disorders via modern machine learning approaches commonly include a single modality and rely on supervised over-parameterized models.However, a single modality provides only a…

In this paper, a neural architecture search (NAS) framework is proposed for 3D medical image segmentation, to automatically optimize a neural architecture from a large design space. Our NAS framework searches the structure of each layer…

Machine Learning · Computer Science 2021-10-28 Sungwoong Kim , Ildoo Kim , Sungbin Lim , Woonhyuk Baek , Chiheon Kim , Hyungjoo Cho , Boogeon Yoon , Taesup Kim

Self-supervised pretraining has become the mainstream approach for learning MRI representations from unlabeled scans. However, most existing objectives still treat each scan primarily as static aggregations of slices, patches or volumes. We…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Yu Wang , Qingchao Chen

Segmenting healthy tissue structures alongside lesions in brain Magnetic Resonance Images (MRI) remains a challenge for today's algorithms due to lesion-caused disruption of the anatomy and lack of jointly labeled training datasets, where…

Image and Video Processing · Electrical Eng. & Systems 2025-03-26 Meva Himmetoglu , Ilja Ciernik , Ender Konukoglu

When three-dimensional bodies contain thin features, non-trivial topology, or scan-derived surfaces, volumetric meshing can become the dominant bottleneck in simulation workflows. We replace this step with a learned geometric…

Computational Physics · Physics 2026-04-02 WaiChing Sun

Existing learning-based methods to automatically trace axons in 3D brain imagery often rely on manually annotated segmentation labels. Labeling is a labor-intensive process and is not scalable to whole-brain analysis, which is needed for…

Image and Video Processing · Electrical Eng. & Systems 2020-04-22 Tzofi Klinghoffer , Peter Morales , Young-Gyun Park , Nicholas Evans , Kwanghun Chung , Laura J. Brattain

Semi-supervised learning algorithms typically construct a weighted graph of data points to represent a manifold. However, an explicit graph representation is problematic for neural networks operating in the online setting. Here, we propose…

Machine Learning · Computer Science 2019-10-22 Alexander Genkin , Anirvan M. Sengupta , Dmitri Chklovskii

Cognitive neuroscience is enjoying rapid increase in extensive public brain-imaging datasets. It opens the door to large-scale statistical models. Finding a unified perspective for all available data calls for scalable and automated…

Machine Learning · Statistics 2019-05-16 Arthur Mensch , Julien Mairal , Danilo Bzdok , Bertrand Thirion , Gaël Varoquaux

We propose a novel neural architecture for representing 3D surfaces, which harnesses two complementary shape representations: (i) an explicit representation via an atlas, i.e., embeddings of 2D domains into 3D; (ii) an implicit-function…

Computer Vision and Pattern Recognition · Computer Science 2020-10-20 Omid Poursaeed , Matthew Fisher , Noam Aigerman , Vladimir G. Kim

Lesion detection in brain Magnetic Resonance Images (MRI) remains a challenging task. State-of-the-art approaches are mostly based on supervised learning making use of large annotated datasets. Human beings, on the other hand, even…

Computer Vision and Pattern Recognition · Computer Science 2018-06-14 Xiaoran Chen , Ender Konukoglu

Despite the remarkable performance of supervised medical image segmentation models, relying on a large amount of labeled data is impractical in real-world situations. Semi-supervised learning approaches aim to alleviate this challenge using…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Yunyao Lu , Yihang Wu , Ahmad Chaddad , Tareef Daqqaq , Reem Kateb

Detailed whole brain segmentation is an essential quantitative technique, which provides a non-invasive way of measuring brain regions from a structural magnetic resonance imaging (MRI). Recently, deep convolution neural network (CNN) has…

Computer Vision and Pattern Recognition · Computer Science 2019-03-29 Yuankai Huo , Zhoubing Xu , Yunxi Xiong , Katherine Aboud , Prasanna Parvathaneni , Shunxing Bao , Camilo Bermudez , Susan M. Resnick , Laurie E. Cutting , Bennett A. Landman

In this study, we proposed and validated a multi-atlas guided 3D fully convolutional network (FCN) ensemble model (M-FCN) for segmenting brain regions of interest (ROIs) from structural magnetic resonance images (MRIs). One major limitation…

Computer Vision and Pattern Recognition · Computer Science 2023-08-11 Jiong Wu , Xiaoying Tang

Current neuroimaging techniques provide paths to investigate the structure and function of the brain in vivo and have made great advances in understanding Alzheimer's disease (AD). However, the group-level analyses prevalently used for…

Quantitative Methods · Quantitative Biology 2021-05-31 Nanyan Zhu , Chen Liu , Xinyang Feng , Dipika Sikka , Sabrina Gjerswold-Selleck , Scott A. Small , Jia Guo