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Computational models and simulations are not just appealing because of their intrinsic characteristics across spatiotemporal scales, scalability, and predictive power, but also because the set of problems in cancer biomedicine that can be…

Tissues and Organs · Quantitative Biology 2023-11-01 Nicolò Cogno , Cristian Axenie , Roman Bauer , Vasileios Vavourakis

Increased healthcare demand is significantly straining European services. Digital solutions including advanced modelling techniques offer a promising solution to optimising patient flow without impacting day-to-day healthcare provision. In…

Computers and Society · Computer Science 2024-10-21 Alison N. O'Connor , Stephen E. Ryan , Gauri Vaidya , Paul Harford , Meghana Kshirsagar

College counseling centers in various universities have been tasked with the important responsibility of attending to the mental health needs of their students. Owing to the unprecedented recent surge of demand for such services, college…

Agent-based modelling and simulation offers a new and exciting way of understanding the world of work. In this paper we describe the development of an agent-based simulation model, designed to help to understand the relationship between…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Peer-Olaf Siebers , Uwe Aickelin , Helen Celia , Christopher Clegg

Diagnostic clinics are among healthcare facilities that suffer from long waiting times which can cause medical issues and lead to increases in patient no-shows. Reducing waiting times without significant capital investments is a challenging…

Optimization and Control · Mathematics 2020-04-20 Mahsa Kiani , Burak Eksioglu , Tugce Isik , Alexandria Thomas , John Gilpin

Radiation therapy is an effective and widely accepted form of treatment for many types of cancer that requires extensive computerized planning. Unfortunately, current treatment planning systems have limited or no visual aid that combines…

Graphics · Computer Science 2018-11-30 Felix G. Hamza-Lup , Ivan Sopin , Omar Zeidan

Critical infrastructures face demanding challenges due to natural and human-generated threats, such as pandemics, workforce shortages or cyber-attacks, which might severely compromise service quality. To improve system resilience,…

Multiagent Systems · Computer Science 2025-02-11 David Carramiñana , Ana M. Bernardos , Juan A. Besada , José R. Casar

We propose a simulation-optimization-based methodology to improve the way that organ transplant offers are made to potential recipients. Our policy can be applied to all types of organs, is implemented starting at the local level, is…

Medical Physics · Physics 2022-12-01 Ignacio Erazo , David Goldsman , Pinar Keskinocak , Joel Sokol

The number of new cancer cases is expected to increase by about 50% in the next 20 years, and the need for chemotherapy treatments will increase accordingly. Chemotherapy treatments are usually performed in outpatient cancer centers where…

Optimization and Control · Mathematics 2023-09-15 Giuliana Carello , Mauro Passacantando , Elena Tanfani

Accurate modeling of the patient flow within an Emergency Department (ED) is required by all studies dealing with the increasing and well-known problem of overcrowding. Since Discrete Event Simulation (DES) models are often adopted with the…

Optimization and Control · Mathematics 2021-02-02 A. De Santis , T. Giovannelli , S. Lucidi , M. Messedaglia , M. Roma

Many advances in research regarding immuno-interactions with cancer were developed with the help of ordinary differential equation (ODE) models. These models, however, are not effectively capable of representing problems involving…

Computational Engineering, Finance, and Science · Computer Science 2013-06-03 Grazziela P. Figueredo , Peer-Olaf Siebers , Uwe Aickelin

Online mental health communities (OMHCs) are an effective and accessible channel to give and receive social support for individuals with mental and emotional issues. However, a key challenge on these platforms is finding suitable partners…

Human-Computer Interaction · Computer Science 2023-03-21 Yuhan Liu , Anna Fang , Glen Moriarty , Robert Kraut , Haiyi Zhu

Computational systems and methods are often being used in biological research, including the understanding of cancer and the development of treatments. Simulations of tumor growth and its response to different drugs are of particular…

Patient scheduling is a difficult task involving stochastic factors such as the unknown arrival times of patients. Similarly, the scheduling of radiotherapy for cancer treatments needs to handle patients with different urgency levels when…

Machine Learning · Computer Science 2022-10-25 Tu-San Pham , Antoine Legrain , Patrick De Causmaecker , Louis-Martin Rousseau

The predicted increase in the number of patients receiving radiation therapy (RT) to treat cancer calls for an optimized use of resources. To manually schedule patients on the linear accelerators delivering RT is a time-consuming and…

Optimization and Control · Mathematics 2023-03-29 Sara Frimodig , Carole Mercier , Geert De Kerf

We present discrete-event simulation models of the operations of primary health centres (PHCs) in the Indian context. Our PHC simulation models incorporate four types of patients seeking medical care: outpatients, inpatients, childbirth…

Computers and Society · Computer Science 2021-09-03 Mohd Shoaib , Varun Ramamohan

Although there are various types of cancer treatments, none of these currently take into account the effect of ageing of the immune system and hence altered responses to cancer. Recent studies have shown that in vitro stimulation of T cells…

Computational Engineering, Finance, and Science · Computer Science 2013-06-13 Grazziela P. Figueredo , Uwe Aickelin

The flexibility level allowed in nursing care delivery and uncertainty in infusion durations are very important factors to be considered during the chemotherapy schedule generation task. The nursing care delivery scheme employed in an…

Optimization and Control · Mathematics 2025-01-17 Serhat Gul

This study examined a simulated confined space modelled as a hospital waiting area, where people who could have underlying conditions congregate and mix with potentially infectious individuals. It further investigated the impact of the…

Multiagent Systems · Computer Science 2021-05-24 J. A. Sarumi , E. C. Onwubiko , O. L. A. Ogunjimi

Medical tourists face a scheduling problem that differs from that of local patients. Treatment delays extend not just care delivery time, but also accommodation and travel costs. This study develops a hybrid agent-based and discrete-event…

Performance · Computer Science 2026-05-20 Melika Baghi , Hadi Mosadegh
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