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In the field of computational pathology, the use of decision support systems powered by state-of-the-art deep learning solutions has been hampered by the lack of large labeled datasets. Until recently, studies relied on datasets in the…

Endometrial cancer, the fourth most common cancer in females in the United States, with the lifetime risk for developing this disease is approximately 2.8% in women. Precise histologic evaluation and molecular classification of endometrial…

The computer-aided analysis of medical scans is a longstanding goal in the medical imaging field. Currently, deep learning has became a dominant methodology for supporting pathologists and radiologist. Deep learning algorithms have been…

Segmentation of Prostate Cancer (PCa) tissues from Gleason graded histopathology images is vital for accurate diagnosis. Although deep learning (DL) based segmentation methods achieve state-of-the-art accuracy, they rely on large datasets…

Histopathological images (HI) encrypt resolution dependent heterogeneous textures & diverse color distribution variability, manifesting in micro-structural surface tissue convolutions. Also, inherently high coherency of cancerous cells…

The rapidly emerging field of deep learning-based computational pathology has demonstrated promise in developing objective prognostic models from histology whole slide images. However, most prognostic models are either based on histology or…

The automated segmentation of cancer tissue in histopathology images can help clinicians to detect, diagnose, and analyze such disease. Different from other natural images used in many convolutional networks for benchmark, histopathology…

In pathological research, education, and clinical practice, the decision-making process based on pathological images is critically important. This significance extends to digital pathology image analysis: its adequacy is demonstrated by the…

Segmentation of histopathology sections is an ubiquitous requirement in digital pathology and due to the large variability of biological tissue, machine learning techniques have shown superior performance over standard image processing…

In computational pathology, automatic nuclei instance segmentation plays an essential role in whole slide image analysis. While many computerized approaches have been proposed for this task, supervised deep learning (DL) methods have shown…

The registration of pathological images plays an important role in medical applications. Despite its significance, most researchers in this field primarily focus on the registration of normal tissue into normal tissue. The negative impact…

Determining early-stage prognostic markers and stratifying patients for effective treatment are two key challenges for improving outcomes for melanoma patients. Previous studies have used tumour transcriptome data to stratify patients into…

Wounds, such as foot ulcers, pressure ulcers, leg ulcers, and infected wounds, come up with substantial problems for healthcare professionals. Prompt and accurate segmentation is crucial for effective treatment. However, contemporary…

In many histopathology tasks, sample classification depends on morphological details in tissue or single cells that are only visible at the highest magnification. For a pathologist, this implies tedious zooming in and out, while for a…

Semantic segmentation is a crucial task in biomedical image processing, which recent breakthroughs in deep learning have allowed to improve. However, deep learning methods in general are not yet widely used in practice since they require…

We present a pioneering investigation into the application of deep learning techniques to analyze histopathological images for addressing the substantial challenge of automated prognostic prediction. Prognostic prediction poses a unique…

Although CNNs are widely considered as the state-of-the-art models in various applications of image analysis, one of the main challenges still open is the training of a CNN on high resolution images. Different strategies have been proposed…

Cancer is a complex disease that provides various types of information depending on the scale of observation. While most tumor diagnostics are performed by observing histopathological slides, radiology images should yield additional…

Digital pathology (DP) is a new research area which falls under the broad umbrella of health informatics. Owing to its potential for major public health impact, in recent years DP has been attracting much research attention. Nevertheless, a…

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…