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We present two deep generative models based on Variational Autoencoders to improve the accuracy of drug response prediction. Our models, Perturbation Variational Autoencoder and its semi-supervised extension, Drug Response Variational…

Machine Learning · Statistics 2017-07-07 Ladislav Rampasek , Daniel Hidru , Petr Smirnov , Benjamin Haibe-Kains , Anna Goldenberg

The variational autoencoder (VAE) is a popular deep latent variable model used to analyse high-dimensional datasets by learning a low-dimensional latent representation of the data. It simultaneously learns a generative model and an…

Machine Learning · Computer Science 2023-11-21 Mine Öğretir , Siddharth Ramchandran , Dimitrios Papatheodorou , Harri Lähdesmäki

Fault classification in industrial machinery is vital for enhancing reliability and reducing downtime, yet it remains challenging due to the variability of vibration patterns across diverse operating conditions. This study introduces a…

Machine Learning · Computer Science 2025-04-15 Moirangthem Tiken Singh

Learning meaningful representations from medical time series (MedTS) such as ECG or EEG signals is a critical challenge. These signals are often high-dimensional, variable-length and rife with noise. Existing self-supervised approaches,…

Machine Learning · Computer Science 2026-05-04 Huayu Li , ZhengXiao He , Xiwen Chen , Jingjing Wang , Siyuan Tian , Jinghao Wen , Ao Li

We present a novel unified framework that concurrently tackles recognition and future prediction for human hand pose and action modeling. Previous works generally provide isolated solutions for either recognition or prediction, which not…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Yilin Wen , Hao Pan , Takehiko Ohkawa , Lei Yang , Jia Pan , Yoichi Sato , Taku Komura , Wenping Wang

This paper shows that masked autoencoder with extrapolator (ExtraMAE) is a scalable self-supervised model for time series generation. ExtraMAE randomly masks some patches of the original time series and learns temporal dynamics by…

Machine Learning · Computer Science 2022-05-20 Mengyue Zha , SiuTim Wong , Mengqi Liu , Tong Zhang , Kani Chen

Deep latent variable models, trained using variational autoencoders or generative adversarial networks, are now a key technique for representation learning of continuous structures. However, applying similar methods to discrete structures,…

Machine Learning · Computer Science 2018-07-02 Jake Zhao , Yoon Kim , Kelly Zhang , Alexander M. Rush , Yann LeCun

Electromyogram (EMG)-based motion classification using machine learning has been widely employed in applications such as prosthesis control. While previous studies have explored generating synthetic patterns of combined motions to reduce…

Signal Processing · Electrical Eng. & Systems 2025-11-13 Itsuki Yazawa , Akira Furui

Unsupervised learning can leverage large-scale data sources without the need for annotations. In this context, deep learning-based auto encoders have shown great potential in detecting anomalies in medical images. However, state-of-the-art…

Machine Learning · Computer Science 2018-12-17 David Zimmerer , Simon A. A. Kohl , Jens Petersen , Fabian Isensee , Klaus H. Maier-Hein

Sequential recommendation as an emerging topic has attracted increasing attention due to its important practical significance. Models based on deep learning and attention mechanism have achieved good performance in sequential…

Information Retrieval · Computer Science 2021-03-22 Zhe Xie , Chengxuan Liu , Yichi Zhang , Hongtao Lu , Dong Wang , Yue Ding

Multivariate time series anomaly detection is a very common problem in the field of failure prevention. Fast prevention means lower repair costs and losses. The amount of sensors in novel industry systems makes the anomaly detection process…

Machine Learning · Computer Science 2021-11-24 Kamil Faber , Dominik Żurek , Marcin Pietroń , Kamil Piętak

We propose using an adversarial autoencoder (AAE) to replace generative adversarial network (GAN) in the private aggregation of teacher ensembles (PATE), a solution for ensuring differential privacy in speech applications. The AAE…

Sound · Computer Science 2021-10-11 Chao-Han Huck Yang , Sabato Marco Siniscalchi , Chin-Hui Lee

We propose a variational autoencoder (VAE) approach for parameter estimation in nonlinear mixed-effects models based on ordinary differential equations (NLME-ODEs) using longitudinal data from multiple subjects. In moderate dimensions,…

Methodology · Statistics 2026-02-11 Zhe Li , Mélanie Prague , Rodolphe Thiébaut , Quentin Clairon

Electroencephalography (EEG) signals reflect activities on certain brain areas. Effective classification of time-varying EEG signals is still challenging. First, EEG signal processing and feature engineering are time-consuming and highly…

Human-Computer Interaction · Computer Science 2019-08-27 Xiang Zhang , Lina Yao , Xianzhi Wang , Wenjie Zhang , Shuai Zhang , Yunhao Liu

A data-driven framework is proposed towards the end of predictive modeling of complex spatio-temporal dynamics, leveraging nested non-linear manifolds. Three levels of neural networks are used, with the goal of predicting the future state…

Computational Physics · Physics 2020-09-14 Jiayang Xu , Karthik Duraisamy

Deep learning has significantly improved time series classification, yet the lack of explainability in these models remains a major challenge. While Explainable AI (XAI) techniques aim to make model decisions more transparent, their…

Machine Learning · Computer Science 2026-02-16 Yannik Hahn , Antonin Königsfeld , Hasan Tercan , Tobias Meisen

Machine learning (ML) models trained to detect physical-layer threats on one optical fiber system often fail catastrophically when applied to a different system, due to variations in operating wavelength, fiber properties, and network…

Cardiovascular diseases (CVDs) are disorders impacting the heart and circulatory system. These disorders are the foremost and continuously escalating cause of mortality worldwide. One of the main tasks when working with CVDs is analyzing…

Signal Processing · Electrical Eng. & Systems 2026-04-29 Ivan Sviridov , Konstantin Egorov

Despite recent successes in synthesizing faces and bedrooms, existing generative models struggle to capture more complex image types, potentially due to the oversimplification of their latent space constructions. To tackle this issue,…

Machine Learning · Computer Science 2018-03-13 Wenling Shang , Kihyuk Sohn , Yuandong Tian

Unsupervised learning is becoming more and more important recently. As one of its key components, the autoencoder (AE) aims to learn a latent feature representation of data which is more robust and discriminative. However, most AE based…

Machine Learning · Computer Science 2019-04-02 Jingcai Guo , Song Guo
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