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Phase separation of intrinsically disordered proteins is important for the formation of membraneless organelles, or biomolecular condensates, which play key roles in the regulation of biochemical processes within cells. In this work, we…

Soft Condensed Matter · Physics 2020-03-18 Antonia Statt , Helena Casademunt , Clifford P. Brangwynne , Athanassios Z. Panagiotopoulos

Recent advances in coarse-grained lattice and off-lattice protein models are reviewed. The sequence dependence of thermodynamical folding properties are investigated and evidence for non-randomness of the binary sequences of good folders…

High Energy Physics - Lattice · Physics 2015-06-25 C. Peterson

Polarity fields are known to exhibit long distance patterns, in both physical and biological systems. The mechanisms behind such patterns are poorly understood. Here, we describe the dynamics of polarity fields using an original physical…

Biological Physics · Physics 2019-07-24 Maryam Aliee , Arezki Boudaoud

In E. coli the determination of the middle of the cell and the proper placement of the septum is essential to the division of the cell. This step depends on the proteins MinC, MinD, and MinE. Exposure to a constant external field e.g., an…

Subcellular Processes · Quantitative Biology 2007-05-23 Paisan Kanthang , Waipot Ngamsaad , Charin Modchang , Wannapong Triampo , Narin Nuttawut , I-Ming Tang , Yongwimol Lenbury

Understanding cellular response to mechanical forces is immensely important for a plethora of biological processes. Focal adhesions are multi-molecular protein assemblies that connect the cell to the extracellular matrix and play a pivotal…

Biological Physics · Physics 2019-10-25 Rumi De

The building of minimal self-reproducing systems with a physical embodiment (generically called protocells) is a great challenge, with implications for both theory and applied sciences. Although the classical view of a living protocell…

Cell Behavior · Quantitative Biology 2009-09-29 Harold Fellermann , Ricard V. Solé

This study introduces a pore morphology algorithm that emphasizes the central role of topology in multiphase flow through porous media. Analysis of drainage in lattice-based pore networks identifies two key quantities, the percolation…

Statistical Mechanics · Physics 2025-08-27 Fernando Alonso-Marroquin

In cell membranes, proteins and lipids diffuse in a highly crowded and heterogeneous landscape, where aggregates and dense domains of proteins or lipids obstruct the path of diffusing molecules. In general, hindered motion gives rise to…

Soft Condensed Matter · Physics 2010-06-16 Margaret R. Horton , Felix Höfling , Joachim O. Rädler , Thomas Franosch

Multi-photon split states, where each photon is in a different spatial mode, represent an essential resource for various quantum applications, yet their efficient characterization remains an open problem. Here, we formulate the general…

Quantum Physics · Physics 2023-08-30 Jihua Zhang , Andrey A. Sukhorukov

We establish a complete picture of condensation in the inclusion process in the thermodynamic limit with vanishing diffusion, covering all scaling regimes of the diffusion parameter and including large deviation results for the maximum…

Probability · Mathematics 2021-07-21 Watthanan Jatuviriyapornchai , Paul Chleboun , Stefan Grosskinsky

Proteins are complex biomolecules that perform a variety of crucial functions within living organisms. Designing and generating novel proteins can pave the way for many future synthetic biology applications, including drug discovery.…

The study of protein mass transport via atomistic simulation requires time and length scales beyond the computational capabilities of modern computer systems. The raspberry model for colloidal particles in combination with the mesoscopic…

Soft Condensed Matter · Physics 2017-04-28 Vincent Ustach , Roland Faller

Cell plasma membranes display a dramatically rich structural complexity characterized by functional sub-wavelength domains with specific lipid and protein composition. Under favorable experimental conditions, patterned morphologies can also…

Soft Condensed Matter · Physics 2018-10-02 Nicolas Destainville , Manoel Manghi , Julie Cornet

We perform an analytical investigation of the cell interface dynamics in the framework of a minimal phase field model of cell motility suggested in [1], which consists of two coupled evolution equations for the order parameter and a…

Biological Physics · Physics 2019-10-04 Mohammad Abu Hamed , Alexander A. Nepomnyashchy

In this paper the evolution of a binary mixture in a thin-film geometry with a wall at the top and bottom is considered. By bringing the mixture into its miscibility gap so that no spinodal decomposition occurs in the bulk, a slight…

Using the Fundamental-Measure Density Functional Theory, we have studied theoretically the phase behavior of extremely confined mixtures of parallel hard squares in slit geometry. The pore width is chosen such that configurations consisting…

Soft Condensed Matter · Physics 2020-01-09 Yuri Martinez-Raton , Enrique Velasco

Intracellular processes often rely on the timely encounter of mobile reaction partners, including intermittently motor-driven organelles. The underlying cytoskeletal network presents a complex landscape that both directs particle movement…

Biological Physics · Physics 2025-12-17 Lizzy Teryoshin , Mario Hidalgo-Soria , Elena F. Koslover

Spatial pattern formation is a key feature of many natural systems in physics, chemistry and biology. The essential theoretical issue in understanding pattern formation is to explain how a spatially homogeneous initial state can undergo…

Pattern Formation and Solitons · Physics 2015-06-04 Timothy Killingback , Gregory Loftus , Bala Sundaram

In the manufacturing process of high-performance particulate materials, viscous sintering plays a crucial role, particularly in fields such as polymer processing and additive manufacturing. The interactions between microscopic particles,…

Computational Engineering, Finance, and Science · Computer Science 2024-12-06 Xiaoxu Dai , Bo Qian , Arkadz Kirshtein , Qingcheng Yang

Tracer diffusion in crowded environments is central to many biological and soft matter systems, but quantitative frameworks for linking tracer motion to environmental structure remain limited. Here, we study the transport of rigid tracers…

Soft Condensed Matter · Physics 2026-05-07 Jinseok Lee , Tong Lin , Mengyang Gu , Yimin Luo