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We introduce and discuss a hybrid quantum-mechanics molecular-mechanics (QM-MM) approach for Car-Parrinello DFT simulations with pseudopotentials and planewaves basis, designed for the treatment of periodic systems. In this implementation…

Materials Science · Physics 2016-07-20 Diego Hunt , Veronica M. Sanchez , Damian A. Scherlis

Quantum machine learning (QML) is rapidly transitioning from theoretical promise to practical relevance across data-intensive scientific domains. In this Review, we provide a structured overview of recent advances that bridge foundational…

Quantum Physics · Physics 2026-02-25 Vinit Singh , Amandeep Singh Bhatia , Mandeep Kaur Saggi , Manas Sajjan , Sabre Kais

Virtually all aspects of many-body atomic physics are challenging: experiments are technically demanding, datasets have become enormous, and the memory and CPU requirements for classical simulation of generic quantum systems often scale…

Quantum Gases · Physics 2026-05-19 I. B. Spielman amd J. P. Zwolak

All-atom simulations can provide molecular-level insights into the dynamics of gas-phase, condensed-phase and surface processes. One important requirement is a sufficiently realistic and detailed description of the underlying intermolecular…

Chemical Physics · Physics 2022-06-15 K. Töpfer , M. Upadhyay , M. Meuwly

In this review, we highlight recent developments in the application of machine learning for molecular modeling and simulation. After giving a brief overview of the foundations, components, and workflow of a typical supervised learning…

Data Analysis, Statistics and Probability · Physics 2019-02-21 Mojtaba Haghighatlari , Johannes Hachmann

This Perspective focuses on the several overlaps between quantum algorithms and Monte Carlo methods in the domains of physics and chemistry. We will analyze the challenges and possibilities of integrating established quantum Monte Carlo…

Quantum Physics · Physics 2024-09-26 Guglielmo Mazzola

Numerical simulation of quantum systems is crucial to further our understanding of natural phenomena. Many systems of key interest and importance, in areas such as superconducting materials and quantum chemistry, are thought to be described…

Quantum Physics · Physics 2010-11-17 Katherine L Brown , William J Munro , Vivien M Kendon

Quantum computing has the potential to revolutionize multiple fields by solving complex problems that can not be solved in reasonable time with current classical computers. Nevertheless, the development of quantum computers is still in its…

The future development of quantum technologies relies on creating and manipulating quantum systems of increasing complexity, with key applications in computation, simulation and sensing. This poses severe challenges in the efficient…

Quantum simulators are a promising technology on the spectrum of quantum devices from specialized quantum experiments to universal quantum computers. These quantum devices utilize entanglement and many-particle behaviors to explore and…

A general polarizable embedded (PE) quantum mechanics/molecular mechanics scheme for periodic systems is presented, describing mutual polarization of the two subsystems. The QM system, described with density functional theory (DFT), is…

The difficulty of simulating quantum systems, well-known to quantum chemists, prompted the idea of quantum computation. One can avoid the steep scaling associated with the exact simulation of increasingly large quantum systems on…

Machine learning potentials offer a revolutionary, unifying framework for molecular simulations across scales, from quantum chemistry to coarse-grained models. Here, I explore their potential to dramatically improve accuracy and scalability…

Chemical Physics · Physics 2024-08-26 Gianni De Fabritiis

Molecular Dynamics (MD) simulation is widely used to analyze the properties of molecules and materials. Most practical applications, such as comparison with experimental measurements, designing drug molecules, or optimizing materials, rely…

Chemical Physics · Physics 2018-12-20 Frank Noé

Machine learning (ML) provides a broad spectrum of tools and architectures that enable the transformation of data from simulations and experiments into useful and explainable science, thereby augmenting domain knowledge. Furthermore,…

Plasma Physics · Physics 2024-09-05 Farbod Faraji , Maryam Reza

Machine learning force fields offer the ability to simulate biomolecules with quantum mechanical accuracy while significantly reducing computational costs, attracting growing attention in biophysics. Meanwhile, leveraging the efficiency of…

Chemical Physics · Physics 2025-08-04 Ge Song , Weitao Yang

Computational models are an essential tool for the design, characterization, and discovery of novel materials. Hard computational tasks in materials science stretch the limits of existing high-performance supercomputing centers, consuming…

Quantum Physics · Physics 2024-09-20 Yuri Alexeev , Maximilian Amsler , Paul Baity , Marco Antonio Barroca , Sanzio Bassini , Torey Battelle , Daan Camps , David Casanova , Young Jai Choi , Frederic T. Chong , Charles Chung , Chris Codella , Antonio D. Corcoles , James Cruise , Alberto Di Meglio , Jonathan Dubois , Ivan Duran , Thomas Eckl , Sophia Economou , Stephan Eidenbenz , Bruce Elmegreen , Clyde Fare , Ismael Faro , Cristina Sanz Fernández , Rodrigo Neumann Barros Ferreira , Keisuke Fuji , Bryce Fuller , Laura Gagliardi , Giulia Galli , Jennifer R. Glick , Isacco Gobbi , Pranav Gokhale , Salvador de la Puente Gonzalez , Johannes Greiner , Bill Gropp , Michele Grossi , Emanuel Gull , Burns Healy , Benchen Huang , Travis S. Humble , Nobuyasu Ito , Artur F. Izmaylov , Ali Javadi-Abhari , Douglas Jennewein , Shantenu Jha , Liang Jiang , Barbara Jones , Wibe Albert de Jong , Petar Jurcevic , William Kirby , Stefan Kister , Masahiro Kitagawa , Joel Klassen , Katherine Klymko , Kwangwon Koh , Masaaki Kondo , Doga Murat Kurkcuoglu , Krzysztof Kurowski , Teodoro Laino , Ryan Landfield , Matt Leininger , Vicente Leyton-Ortega , Ang Li , Meifeng Lin , Junyu Liu , Nicolas Lorente , Andre Luckow , Simon Martiel , Francisco Martin-Fernandez , Margaret Martonosi , Claire Marvinney , Arcesio Castaneda Medina , Dirk Merten , Antonio Mezzacapo , Kristel Michielsen , Abhishek Mitra , Tushar Mittal , Kyungsun Moon , Joel Moore , Mario Motta , Young-Hye Na , Yunseong Nam , Prineha Narang , Yu-ya Ohnishi , Daniele Ottaviani , Matthew Otten , Scott Pakin , Vincent R. Pascuzzi , Ed Penault , Tomasz Piontek , Jed Pitera , Patrick Rall , Gokul Subramanian Ravi , Niall Robertson , Matteo Rossi , Piotr Rydlichowski , Hoon Ryu , Georgy Samsonidze , Mitsuhisa Sato , Nishant Saurabh , Vidushi Sharma , Kunal Sharma , Soyoung Shin , George Slessman , Mathias Steiner , Iskandar Sitdikov , In-Saeng Suh , Eric Switzer , Wei Tang , Joel Thompson , Synge Todo , Minh Tran , Dimitar Trenev , Christian Trott , Huan-Hsin Tseng , Esin Tureci , David García Valinas , Sofia Vallecorsa , Christopher Wever , Konrad Wojciechowski , Xiaodi Wu , Shinjae Yoo , Nobuyuki Yoshioka , Victor Wen-zhe Yu , Seiji Yunoki , Sergiy Zhuk , Dmitry Zubarev

While recent progress in quantum hardware open the door for significant speedup in certain key areas (cryptography, biology, chemistry, optimization, machine learning, etc), quantum algorithms are still hard to implement right, and the…

Programming Languages · Computer Science 2022-04-11 Christophe Chareton , Sébastien Bardin , Dongho Lee , Benoît Valiron , Renaud Vilmart , Zhaowei Xu

Molecular dynamics (MD) has become a powerful tool for studying biophysical systems, due to increasing computational power and availability of software. Although MD has made many contributions to better understanding these complex…

Computational Physics · Physics 2019-09-27 Yihang Wang , Joao Marcelo Lamim Ribeiro , Pratyush Tiwary

In this paper, a methodical approach to evaluate the potential of quantum computing for manufacturing simulation, using the example of multi-axis milling of thin-walled aerospace components, is discussed. A developed approach for…