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Molecular dynamics (MD) is a powerful technique for studying microscopic phenomena, but its computational cost has driven significant interest in the development of deep learning-based surrogate models. We introduce generative modeling of…

Biomolecules · Quantitative Biology 2024-09-27 Bowen Jing , Hannes Stärk , Tommi Jaakkola , Bonnie Berger

A fundamental dilemma in generative modeling persists: iterative diffusion models achieve outstanding fidelity, but at a significant computational cost, while efficient few-step alternatives are constrained by a hard quality ceiling. This…

Machine Learning · Computer Science 2025-09-05 Zidong Wang , Yiyuan Zhang , Xiaoyu Yue , Xiangyu Yue , Yangguang Li , Wanli Ouyang , Lei Bai

Models trained in the context of continual learning (CL) should be able to learn from a stream of data over an undefined period of time. The main challenges herein are: 1) maintaining old knowledge while simultaneously benefiting from it…

Neural and Evolutionary Computing · Computer Science 2019-12-03 Oleksiy Ostapenko , Mihai Puscas , Tassilo Klein , Patrick Jähnichen , Moin Nabi

Recent research efforts in lifelong learning propose to grow a mixture of models to adapt to an increasing number of tasks. The proposed methodology shows promising results in overcoming catastrophic forgetting. However, the theory behind…

Machine Learning · Computer Science 2021-08-30 Fei Ye , Adrian G. Bors

We introduce Midpoint Generative Models (MGM), a principled framework for training one-step generative models. MGM is based on a simple symmetry of Flow Matching with linear interpolation: when the two endpoint distributions coincide, the…

Machine Learning · Computer Science 2026-05-29 Daniil Shlenskii , Nikita Gushchin , Lev Novitskiy , Dmitry V. Dylov , Alexander Korotin

Uncertainty quantification is essential in safety-critical settings--from autonomous driving to aviation, finance, and health--where decisions must rely on conservative bounds rather than point estimates. Predictor-level intervals (e.g.,…

Machine Learning · Computer Science 2026-05-18 Ruirui Liu , Xuejie Hou , Yiping Jiang , Hui Ren

Global ambient air pollution, a transboundary challenge, is typically addressed through interventions relying on data from spatially sparse and heterogeneously placed monitoring stations. These stations often encounter temporal data gaps…

Machine Learning · Computer Science 2024-02-19 Liam J Berrisford , Hugo Barbosa , Ronaldo Menezes

Modern machine learning models are deployed in diverse, non-stationary environments where they must continually adapt to new tasks and evolving knowledge. Continual fine-tuning and in-context learning are costly and brittle, whereas neural…

Machine Learning · Computer Science 2026-03-04 Max S. Bennett , Thomas P. Zollo , Richard Zemel

We establish a general framework that guarantees the preservation of optimal control patterns as the time horizon $[0,T]$ increases and becomes unbounded. A concept of pattern-preserving family of optimal control problems is introduced and…

Optimization and Control · Mathematics 2026-02-24 Matteo Della Rossa , Lorenzo Freddi

Ecological systems are governed by complex interactions which are mainly nonlinear. In order to capture this complexity and nonlinearity, statistical models recently gained popularity. However, although these models are commonly applied in…

Quantitative Methods · Quantitative Biology 2011-07-29 Can Ozan Tan , Uygar Ozesmi , Meryem Beklioglu , Esra Per , Bahtiyar Kurt

Accurate traffic forecasting is crucial for intelligent transportation systems, supporting effective traffic management, congestion reduction, and informed urban planning. However, traditional models often fail to adequately capture the…

Artificial Intelligence · Computer Science 2026-04-21 Dongyi He , Yuanquan Gao , Bin Jiang , He Yan

In recent years, generative pre-trained paradigms such as Large Language Models (LLMs) and Large Vision Models (LVMs) have achieved revolutionary advancements and widespread real-world applications. Particularly, the emergence of…

Computational Engineering, Finance, and Science · Computer Science 2024-06-05 Jiarui Yang , Tao Dai , Naiqi Li , Junxi Wu , Peiyuan Liu , Jinmin Li , Jigang Bao , Haigang Zhang , Shutao Xia

Decision Focused Learning has emerged as a critical paradigm for integrating machine learning with downstream optimisation. Despite its promise, existing methodologies predominantly rely on probabilistic models and focus narrowly on task…

Machine Learning · Computer Science 2025-03-21 Keivan Shariatmadar , Neil Yorke-Smith , Ahmad Osman , Fabio Cuzzolin , Hans Hallez , David Moens

World models have recently re-emerged as a central paradigm for embodied intelligence, robotics, autonomous driving, and model-based reinforcement learning. However, current world model research is often dominated by three partially…

Artificial Intelligence · Computer Science 2026-05-27 Sen Cui , Jingheng Ma

Temporal Interaction Graphs (TIGs) are widely utilized to represent real-world systems. To facilitate representation learning on TIGs, researchers have proposed a series of TIG models. However, these models are still facing two tough gaps…

Artificial Intelligence · Computer Science 2024-03-07 Xi Chen , Siwei Zhang , Yun Xiong , Xixi Wu , Jiawei Zhang , Xiangguo Sun , Yao Zhang , Feng Zhao , Yulin Kang

Recent advances in reinforcement learning have inspired increasing interest in learning user modeling adaptively through dynamic interactions, e.g., in reinforcement learning based recommender systems. Reward function is crucial for most of…

Machine Learning · Computer Science 2021-05-06 Xiaocong Chen , Lina Yao , Xianzhi Wang , Aixin Sun , Wenjie Zhang , Quan Z. Sheng

In real-world applications, machine learning models often become obsolete due to shifts in the joint distribution arising from underlying temporal trends, a phenomenon known as the "concept drift". Existing works propose model-specific…

Machine Learning · Computer Science 2023-10-04 Chia-Yuan Chang , Yu-Neng Chuang , Zhimeng Jiang , Kwei-Herng Lai , Anxiao Jiang , Na Zou

We introduce a novel modeling approach for time series imputation and forecasting, tailored to address the challenges often encountered in real-world data, such as irregular samples, missing data, or unaligned measurements from multiple…

The Global Change Analysis Model (GCAM) simulates complex interactions between the coupled Earth and human systems, providing valuable insights into the co-evolution of land, water, and energy sectors under different future scenarios.…

This paper presents a data-driven model for Linear Time-Invariant (LTI) stochastic systems by sampling from the conditional probability distribution of future outputs given past input-outputs and future inputs. It operates in a fully…

Optimization and Control · Mathematics 2025-11-27 Jiayun Li , Yilin Mo