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Randomized experiments are often performed to study the causal effects of interest. Blocking is a technique to precisely estimate the causal effects when the experimental material is not homogeneous. It involves stratifying the available…

Methodology · Statistics 2023-02-21 Abhishek Kumar Umrawal

A common method to reduce the uncertainty of causal inferences from experiments is to assign treatments in fixed proportions within groups of similar units: blocking. Previous results indicate that one can expect substantial reductions in…

Methodology · Statistics 2015-08-31 Fredrik Sävje

Randomisation is used in experimental design to reduce the prevalence of unanticipated confounders. Complete randomisation can however create unbalanced designs, for example, grouping all samples of the same condition in the same batch.…

Quantitative Methods · Quantitative Biology 2020-07-14 Bram Burger , Marc Vaudel , Harald Barsnes

Evaluating blocked randomized experiments from a potential outcomes perspective has two primary branches of work. The first focuses on larger blocks, with multiple treatment and control units in each block. The second focuses on matched…

Methodology · Statistics 2024-05-31 Nicole E. Pashley , Luke W. Miratrix

Restricting randomization in the design of experiments (e.g., using blocking/stratification, pair-wise matching, or rerandomization) can improve the treatment-control balance on important covariates and therefore improve the estimation of…

Econometrics · Economics 2020-11-02 Brian Quistorff , Gentry Johnson

Researchers often turn to block randomization to increase the precision of their inference or due to practical considerations, such as in multisite trials. However, if the number of treatments under consideration is large it might not be…

Methodology · Statistics 2025-08-26 Taehyeon Koo , Nicole E. Pashley

For obtaining causal inferences that are objective, and therefore have the best chance of revealing scientific truths, carefully designed and executed randomized experiments are generally considered to be the gold standard. Observational…

Applications · Statistics 2008-11-12 Donald B. Rubin

Attacks on the P-value are nothing new, but the recent attacks are increasingly more serious. They come from more mainstream sources, with widening targets such as a call to retire the significance testing altogether. While well meaning, I…

Other Statistics · Statistics 2022-01-11 Yudi Pawitan

The block maximum method, which is widely used in extreme value analysis, uses a generalized extreme value distribution to approximate that of the maximum of m observations. The quality of this approximation depends on the value of m and…

Methodology · Statistics 2026-05-14 Léo R. Belzile , Anthony C. Davison

There is a growing body of work on sorting and selection in models other than the unit-cost comparison model. This work is the first treatment of a natural stochastic variant of the problem where the cost of comparing two elements is a…

Data Structures and Algorithms · Computer Science 2007-10-02 Stanislav Angelov , Keshav Kunal , Andrew McGregor

Experiments deliver credible treatment-effect estimates but, because they are costly, are often restricted to specific sites, small populations, or particular mechanisms. A common practice across several fields is therefore to combine…

Econometrics · Economics 2025-12-30 Aristotelis Epanomeritakis , Davide Viviano

It is standard practice in online retail to run pricing experiments by randomizing at the article-level, i.e. by changing prices of different products to identify treatment effects. Due to customers' cross-price substitution behavior, such…

Applications · Statistics 2024-02-23 Lars Roemheld , Justin Rao

We consider designs for cancer trials which allow each medical centre to treat only a limited number of cancer types with only a limited number of drugs. We specify desirable properties of these designs, and prove some consequences. Then we…

Applications · Statistics 2019-05-31 R. A. Bailey , Peter J. Cameron

Many important economic outcomes result from the combined effects of several choices, so the best option is not determined from each choice in isolation, but depends on how each choice alters total outcomes. We formally show that narrow…

General Economics · Economics 2025-04-08 Francesco Fallucchi , Marc Kaufmann

Following Fisher, it is widely believed that randomization "relieves the experimenter from the anxiety of considering innumerable causes by which the data may be disturbed." In particular, it is said to control for known and unknown…

Methodology · Statistics 2017-10-02 Uwe Saint-Mont

Postselection is the process of discarding outcomes from statistical trials that are not the event one desires. Postselection can be useful in many applications where the cost of getting the wrong event is implicitly high. However, unless…

Quantum Physics · Physics 2015-09-01 Joshua Combes , Christopher Ferrie

Game theory is often used as a tool to analyze decentralized systems and their properties, in particular, blockchains. In this note, we take the opposite view. We argue that blockchains can and should be used to implement economic…

Computer Science and Game Theory · Computer Science 2020-10-02 Akaki Mamageishvili , Jan Christoph Schlegel

We formally study iterated block ciphers that alternate between two sequences of independent and identically distributed (i.i.d.) rounds. It is demonstrated that, in some cases the effect of alternating increases security, while in other…

Cryptography and Security · Computer Science 2013-09-12 John O. Pliam

Biased-coin designs are used in clinical trials to allocate treatments with some randomness while maintaining approximately equal allocation. More recent rules are compared with Efron's [Biometrika 58 (1971) 403-417] biased-coin rule and…

Methodology · Statistics 2014-05-21 Anthony C. Atkinson

Recently, there as been an increasing interest in the use of heavily restricted randomization designs which enforces balance on observed covariates in randomized controlled trials. However, when restrictions are strict, there is a risk that…

Methodology · Statistics 2021-10-15 Mattias Nordin , Mårten Schultzberg
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