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An overview of current multiple alignment systems to date are described.The useful algorithms, the procedures adopted and their limitations are presented.We also present the quality of the alignments obtained and in which cases(kind of…

Data Structures and Algorithms · Computer Science 2009-01-20 Fahad Saeed , Ashfaq Khokhar

Deep reinforcement learning has shown remarkable success in the past few years. Highly complex sequential decision making problems have been solved in tasks such as game playing and robotics. Unfortunately, the sample complexity of most…

Machine Learning · Computer Science 2020-12-03 Aske Plaat , Walter Kosters , Mike Preuss

Deep convolutional neural networks (CNNs) have shown excellent performance in object recognition tasks and dense classification problems such as semantic segmentation. However, training deep neural networks on large and sparse datasets is…

Computer Vision and Pattern Recognition · Computer Science 2017-12-25 Lorenz Berger , Eoin Hyde , M. Jorge Cardoso , Sebastien Ourselin

Visual-inertial systems rely on precise calibrations of both camera intrinsics and inter-sensor extrinsics, which typically require manually performing complex motions in front of a calibration target. In this work we present a novel…

Multi-view learning is frequently used in data science. The pairwise correlation maximization is a classical approach for exploring the consensus of multiple views. Since the pairwise correlation is inherent for two views, the extensions to…

Machine Learning · Computer Science 2022-01-31 Jiawang Nie , Li Wang , Zequn Zheng

We proposed a probabilistic algorithm to solve the Multiple Sequence Alignment problem. The algorithm is a Simulated Annealing (SA) that exploits the representation of the Multiple Alignment between $D$ sequences as a directed polymer in…

Genomics · Quantitative Biology 2016-08-16 M. Hernández-Guía , R. Mulet , S. Rodríguez-Pérez

Deep reinforcement learning has shown remarkable success in the past few years. Highly complex sequential decision making problems from game playing and robotics have been solved with deep model-free methods. Unfortunately, the sample…

Machine Learning · Computer Science 2021-07-20 Aske Plaat , Walter Kosters , Mike Preuss

Feature matching and finding correspondences between endoscopic images is a key step in many clinical applications such as patient follow-up and generation of panoramic image from clinical sequences for fast anomalies localization.…

Computer Vision and Pattern Recognition · Computer Science 2022-08-25 Manel Farhat , Houda Chaabouni-Chouayakh , Achraf Ben-Hamadou

The increasing demand for autonomous systems in complex and dynamic environments has driven significant research into intelligent path planning methodologies. For decades, graph-based search algorithms, linear programming techniques, and…

Deep learning has been widely used for protein engineering. However, it is limited by the lack of sufficient experimental data to train an accurate model for predicting the functional fitness of high-order mutants. Here, we develop SESNet,…

Quantitative Methods · Quantitative Biology 2023-04-10 Mingchen Li , Liqi Kang , Yi Xiong , Yu Guang Wang , Guisheng Fan , Pan Tan , Liang Hong

Ongoing studies have identified similarities between neural representations in biological networks and in deep artificial neural networks. This has led to renewed interest in developing analogies between the backpropagation learning…

Neural and Evolutionary Computing · Computer Science 2019-06-11 Theodore H. Moskovitz , Ashok Litwin-Kumar , L. F. Abbott

Identifying interacting partners from two sets of protein sequences has important applications in computational biology. Interacting partners share similarities across species due to their common evolutionary history, and feature…

Biomolecules · Quantitative Biology 2024-12-31 Umberto Lupo , Damiano Sgarbossa , Martina Milighetti , Anne-Florence Bitbol

Gene selection plays a pivotal role in oncology research for improving outcome prediction accuracy and facilitating cost-effective genomic profiling for cancer patients. This paper introduces two gene selection strategies for deep…

Genomics · Quantitative Biology 2024-03-05 Akhila Krishna , Ravi Kant Gupta , Pranav Jeevan , Amit Sethi

Deep learning techniques, such as Deep Boltzmann Machines (DBMs), have received considerable attention over the past years due to the outstanding results concerning a variable range of domains. One of the main shortcomings of these…

Machine Learning · Computer Science 2021-01-15 Leandro Aparecido Passos , João Paulo Papa

In this paper, we present a novel approach to accelerate the Bayesian inference process, focusing specifically on the nested sampling algorithms. Bayesian inference plays a crucial role in cosmological parameter estimation, providing a…

Instrumentation and Methods for Astrophysics · Physics 2024-10-17 Isidro Gómez-Vargas , J. Alberto Vázquez

This paper describes a method to efficiently retrieve protein database sequences similar to a query sequence, while allowing for significant numbers of mutations. We call this method SEQR for SEQuence Retrieval. This approach increases the…

Genomics · Quantitative Biology 2018-11-05 David I. Hurwitz , Lianyi Han , Lewis Y. Geer

String matching algorithm plays the vital role in the Computational Biology. The functional and structural relationship of the biological sequence is determined by similarities on that sequence. For that, the researcher is supposed to aware…

Data Structures and Algorithms · Computer Science 2014-01-30 Pandiselvam. P , Marimuthu. T , Lawrance. R

Sequence-based protein homology detection has been extensively studied and so far the most sensitive method is based upon comparison of protein sequence profiles, which are derived from multiple sequence alignment (MSA) of sequence homologs…

Quantitative Methods · Quantitative Biology 2015-06-18 Jianzhu Ma , Sheng Wang , Zhiyong Wang , Jinbo Xu

Real-world face detection and alignment demand an advanced discriminative model to address challenges by pose, lighting and expression. Illuminated by the deep learning algorithm, some convolutional neural networks based face detection and…

Computer Vision and Pattern Recognition · Computer Science 2017-08-01 Weilin Cong , Sanyuan Zhao , Hui Tian , Jianbing Shen

Exhaustive enumeration of all possible join orders is often avoided, and most optimizers leverage heuristics to prune the search space. The design and implementation of heuristics are well-understood when the cost model is roughly linear,…

Databases · Computer Science 2019-01-14 Sanjay Krishnan , Zongheng Yang , Ken Goldberg , Joseph Hellerstein , Ion Stoica