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Interpretability is an important aspect of the trustworthiness of a model's predictions. Transformer's predictions are widely explained by the attention weights, i.e., a probability distribution generated at its self-attention unit (head).…

Computation and Language · Computer Science 2021-06-03 Rishabh Bhardwaj , Navonil Majumder , Soujanya Poria , Eduard Hovy

Being able to interpret, or explain, the predictions made by a machine learning model is of fundamental importance. This is especially true when there is interest in deploying data-driven models to make high-stakes decisions, e.g. in…

Machine Learning · Computer Science 2019-10-01 An-phi Nguyen , María Rodríguez Martínez

Machine learning accelerates molecular property prediction, yet state-of-the-art Large Language Models and Graph Neural Networks operate as black boxes. In drug discovery, where safety is critical, this opacity risks masking false…

Machine Learning · Computer Science 2026-03-03 Oscar Rivera , Ziqing Wang , Matthieu Dagommer , Abhishek Pandey , Kaize Ding

Hybrid models composing mechanistic ODE-based dynamics with flexible and expressive neural network components have grown rapidly in popularity, especially in scientific domains where such ODE-based modeling offers important interpretability…

Machine Learning · Computer Science 2026-02-02 Bob Junyi Zou , Matthew E. Levine , Dessi P. Zaharieva , Ramesh Johari , Emily B. Fox

Uncertainty quantification is critical for ensuring robustness in high-stakes machine learning applications. We introduce HybridFlow, a modular hybrid architecture that unifies the modeling of aleatoric and epistemic uncertainty by…

Machine Learning · Computer Science 2025-10-16 Peter Van Katwyk , Karianne J. Bergen

The advancement of in-vehicle sensors provides abundant datasets to estimate parameters of car-following models that describe driver behaviors. The question of parameter identifiability of such models (i.e., whether it is possible to infer…

Dynamical Systems · Mathematics 2022-02-21 Yanbing Wang , Maria Laura Delle Monache , Daniel B. Work

There is a need of ensuring machine learning models that are interpretable. Higher interpretability of the model means easier comprehension and explanation of future predictions for end-users. Further, interpretable machine learning models…

Machine Learning · Computer Science 2020-08-17 Gregor Stiglic , Primoz Kocbek , Nino Fijacko , Marinka Zitnik , Katrien Verbert , Leona Cilar

The use of Hodgkin-Huxley (HH) equations abounds in the literature, but the identifiability of the HH model parameters has not been broadly considered. Identifiability analysis addresses the question of whether it is possible to estimate…

Neurons and Cognition · Quantitative Biology 2015-11-18 Olivia J. Walch , Marisa C. Eisenberg

Deep generative models such as flow matching and diffusion models have shown great potential in learning complex distributions and dynamical systems, but often act as black-boxes, neglecting underlying physics. In contrast, physics-based…

Machine Learning · Computer Science 2026-04-28 Gurjeet Sangra Singh , Frantzeska Lavda , Giangiacomo Mercatali , Alexandros Kalousis

To operate process engineering systems in a safe and reliable manner, predictive models are often used in decision making. In many cases, these are mechanistic first principles models which aim to accurately describe the process. In…

Machine Learning · Computer Science 2022-05-20 Timur Bikmukhametov , Johannes Jäschke

Missing data problems arise in many applied research studies. They may jeopardize statistical inference of the model of interest, if the missing mechanism is nonignorable, that is, the missing mechanism depends on the missing values…

Statistics Theory · Mathematics 2015-09-15 Wang Miao , Peng Ding , Zhi Geng

The rapid adoption of complex Artificial Intelligence (AI) and Machine Learning (ML) models has led to their characterization as black boxes due to the difficulty of explaining their internal decision-making processes. This lack of…

Machine Learning · Computer Science 2026-01-13 Silvia Ruiz-España , Laura Arnal , François Signol , Juan-Carlos Perez-Cortes , Joaquim Arlandis

We review generalized additive models as a type of ``transparent'' model that has recently seen renewed interest in the deep learning community as neural additive models. We highlight multiple types of nonidentifiability in this model class…

Machine Learning · Computer Science 2025-04-15 Xinyu Zhang , Julien Martinelli , ST John

Interpretability and uncertainty quantification in machine learning can provide justification for decisions, promote scientific discovery and lead to a better understanding of model behavior. Symbolic regression provides inherently…

Neural and Evolutionary Computing · Computer Science 2022-11-23 G. F. Bomarito , P. E. Leser , N. C. M Strauss , K. M. Garbrecht , J. D. Hochhalter

A salient approach to interpretable machine learning is to restrict modeling to simple models. In the Bayesian framework, this can be pursued by restricting the model structure and prior to favor interpretable models. Fundamentally,…

Machine Learning · Computer Science 2020-09-08 Homayun Afrabandpey , Tomi Peltola , Juho Piironen , Aki Vehtari , Samuel Kaski

While the uptake of data-driven approaches for materials science and chemistry is at an exciting, early stage, to realise the true potential of machine learning models for successful scientific discovery, they must have qualities beyond…

Materials Science · Physics 2022-06-28 Felipe Oviedo , Juan Lavista Ferres , Tonio Buonassisi , Keith Butler

Machine learning models have had discernible achievements in a myriad of applications. However, most of these models are black-boxes, and it is obscure how the decisions are made by them. This makes the models unreliable and untrustworthy.…

Machine Learning · Computer Science 2020-03-23 Raha Moraffah , Mansooreh Karami , Ruocheng Guo , Adrienne Raglin , Huan Liu

This paper presents a systematic literature review (SLR) on the explainability and interpretability of machine learning (ML) models within the context of predictive process mining, using the PRISMA framework. Given the rapid advancement of…

Machine Learning · Computer Science 2024-01-01 Nijat Mehdiyev , Maxim Majlatow , Peter Fettke

The healthcare domain is one of the most exciting application areas for machine learning, but a lack of model transparency contributes to a lag in adoption within the industry. In this work, we explore the current art of explainability and…

Computation and Language · Computer Science 2021-07-14 Mitchell Naylor , Christi French , Samantha Terker , Uday Kamath

Although a recent shift has been made in the field of predictive process monitoring to use models from the explainable artificial intelligence field, the evaluation still occurs mainly through performance-based metrics, thus not accounting…

Machine Learning · Computer Science 2023-08-01 Alexander Stevens , Johannes De Smedt
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