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The past decade has witnessed the development and success of coarse-grained network models of proteins for predicting many equilibrium properties related to collective modes of motion. Curiously, the results are usually robust towards the…

Biomolecules · Quantitative Biology 2010-02-04 Canan Atilgan , Osman Burak Okan , Ali Rana Atilgan

Residual networks are an Euler discretization of solutions to Ordinary Differential Equations (ODE). This paper explores a deeper relationship between Transformer and numerical ODE methods. We first show that a residual block of layers in…

Computation and Language · Computer Science 2022-04-13 Bei Li , Quan Du , Tao Zhou , Yi Jing , Shuhan Zhou , Xin Zeng , Tong Xiao , JingBo Zhu , Xuebo Liu , Min Zhang

Deep neural networks have become invaluable tools for supervised machine learning, e.g., classification of text or images. While often offering superior results over traditional techniques and successfully expressing complicated patterns in…

Machine Learning · Computer Science 2019-02-19 Eldad Haber , Lars Ruthotto

Reaction networks are systems in which the populations of a finite number of species evolve through predefined interactions. Such networks are found as modeling tools in many biological disciplines such as biochemistry, ecology,…

Molecular Networks · Quantitative Biology 2015-06-15 Ankit Gupta , Corentin Briat , Mustafa Khammash

It has been found that residual networks are an Euler discretization of solutions to Ordinary Differential Equations (ODEs). In this paper, we explore a deeper relationship between Transformer and numerical methods of ODEs. We show that a…

Computation and Language · Computer Science 2021-04-07 Bei Li , Quan Du , Tao Zhou , Shuhan Zhou , Xin Zeng , Tong Xiao , Jingbo Zhu

Neural networks are widely used to approximate unknown functions in control. A common neural network architecture uses a single hidden layer (i.e. a shallow network), in which the input parameters are fixed in advance and only the output…

Machine Learning · Computer Science 2024-10-08 Andrew Lamperski , Siddharth Salapaka

The performance of deep network learning strongly depends on the choice of the non-linear activation function associated with each neuron. However, deciding on the best activation is non-trivial, and the choice depends on the architecture,…

Machine Learning · Computer Science 2020-02-05 Alejandro Molina , Patrick Schramowski , Kristian Kersting

In the study of reaction networks and the polynomial dynamical systems that they generate, special classes of networks with important properties have been identified. These include reversible, weakly reversible}, and, more recently,…

Dynamical Systems · Mathematics 2020-07-30 David F. Anderson , James D. Brunner , Gheorghe Craciun , Matthew D. Johnston

We investigate what can be learned from translating numerical algorithms into neural networks. On the numerical side, we consider explicit, accelerated explicit, and implicit schemes for a general higher order nonlinear diffusion equation…

Numerical Analysis · Mathematics 2021-05-18 Tobias Alt , Pascal Peter , Joachim Weickert , Karl Schrader

The choice of activation function can significantly influence the performance of neural networks. The lack of guiding principles for the selection of activation function is lamentable. We try to address this issue by introducing our…

Machine Learning · Computer Science 2018-10-16 Yiwei Li , Enzhi Li

Neural networks are a powerful class of functions that can be trained with simple gradient descent to achieve state-of-the-art performance on a variety of applications. Despite their practical success, there is a paucity of results that…

Machine Learning · Computer Science 2017-03-06 Bo Xie , Yingyu Liang , Le Song

Recurrent neural networks (RNNs) are particularly well-suited for modeling long-term dependencies in sequential data, but are notoriously hard to train because the error backpropagated in time either vanishes or explodes at an exponential…

Machine Learning · Computer Science 2019-08-28 Anil Kag , Ziming Zhang , Venkatesh Saligrama

Here we focus on the challenge of verifying the correctness of molecular implementations of abstract chemical reaction networks, where operation in a well-mixed "soup" of molecules is stochastic, asynchronous, concurrent, and often involves…

Computational Engineering, Finance, and Science · Computer Science 2019-10-01 Seung Woo Shin , Chris Thachuk , Erik Winfree

Deep learning has the potential to revolutionize quantum chemistry as it is ideally suited to learn representations for structured data and speed up the exploration of chemical space. While convolutional neural networks have proven to be…

We present and review an algorithmic and theoretical framework for improving neural network architecture design via momentum. As case studies, we consider how momentum can improve the architecture design for recurrent neural networks…

Machine Learning · Computer Science 2021-10-20 Bao Wang , Hedi Xia , Tan Nguyen , Stanley Osher

Transformer-based deep neural networks have revolutionized the field of molecular-related prediction tasks by treating molecules as symbolic sequences. These models have been successfully applied in various organic chemical applications by…

Chemical Physics · Physics 2023-11-14 Tatsuya Sagawa , Ryosuke Kojima

The expressive power of neural networks is important for understanding deep learning. Most existing works consider this problem from the view of the depth of a network. In this paper, we study how width affects the expressiveness of neural…

Machine Learning · Computer Science 2017-11-02 Zhou Lu , Hongming Pu , Feicheng Wang , Zhiqiang Hu , Liwei Wang

Neural ordinary differential equations describe how values change in time. This is the reason why they gained importance in modeling sequential data, especially when the observations are made at irregular intervals. In this paper we propose…

Machine Learning · Computer Science 2021-10-26 Marin Biloš , Johanna Sommer , Syama Sundar Rangapuram , Tim Januschowski , Stephan Günnemann

Feed-forward neural networks (NN) are a staple machine learning method widely used in many areas of science and technology. While even a single-hidden layer NN is a universal approximator, its expressive power is limited by the use of…

Machine Learning · Statistics 2023-09-28 Sergei Manzhos , Manabu Ihara

Neural networks are powerful function estimators, leading to their status as a paradigm of choice for modeling structured data. However, unlike other structured representations that emphasize the modularity of the problem -- e.g., factor…

Machine Learning · Computer Science 2022-06-20 Tsvetomila Mihaylova , Vlad Niculae , André F. T. Martins
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