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X-ray computed tomography (CT) has an indispensable role in constructing 3D images of objects made from light materials. However, limited by absorption coefficients, X-rays cannot deeply penetrate materials such as copper and lead. Here we…

Instrumentation and Detectors · Physics 2015-01-29 Burkhant Suerfu , Christopher G. Tully

Model-based treatment planning for transcranial ultrasound therapy typically involves mapping the acoustic properties of the skull from an x-ray computed tomography (CT) image of the head. Here, three methods for generating pseudo-CT images…

In clinical CT, the x-ray source emits polychromatic x-rays, which are detected in the current-integrating mode. This physical process is accurately described by an energy-dependent non-linear integral model on the basis of the Beer-Lambert…

Medical Physics · Physics 2018-01-11 Wenxiang Cong , Ge Wang

Dual-energy computed tomography (DECT) utilizes separate X-ray energy spectra to improve multi-material decomposition (MMD) for various diagnostic applications. However accurate decomposing more than two types of material remains…

Image and Video Processing · Electrical Eng. & Systems 2023-11-02 Di Xu , Qihui Lyu , Dan Ruan , Ke Sheng

Computed tomography (CT) images are frequently degraded by acquisition artifacts, including noise, blur, streaking, aliasing, and metal artifacts. Yet CT enhancement is still largely evaluated using image quality metrics with limited…

For medical cone-beam computed tomography (CBCT) imaging, the native receptor array of the flat-panel detector (FPD) is usually binned into a reduced matrix size. By doing so, the signal readout speed can be increased by over 4-9 times at…

Medical Physics · Physics 2022-10-18 Ting Su , Jiongtao Zhu , Xin Zhang , Dong Zeng , Yuhang Tan , Han Cui , Hairong Zheng , Jianhua Ma , Dong Liang , Yongshuai Ge

The transmission electron microscope facilitates the highest-resolution imaging of any instrument ever created, and its limiting factor is no longer spatial resolution but dose efficiency. Low electron doses avoid sample damage but produce…

Machine Learning · Computer Science 2026-05-08 Georgia Channing , Debora Keller , Marta D. Rossell , Philip Torr , Stig Helveg , Henrik Eliasson

The ability to synthesise Computed Tomography images - commonly known as pseudo CT, or pCT - from MRI input data is commonly assessed using an intensity-wise similarity, such as an L2-norm between the ground truth CT and the pCT. However,…

Image and Video Processing · Electrical Eng. & Systems 2020-04-15 Kerstin Kläser , Thomas Varsavsky , Pawel Markiewicz , Tom Vercauteren , David Atkinson , Kris Thielemans , Brian Hutton , M Jorge Cardoso , Sebastien Ourselin

X-ray computed tomography (XCT) is an important tool for high-resolution non-destructive characterization of additively-manufactured metal components. XCT reconstructions of metal components may have beam hardening artifacts such as cupping…

Image and Video Processing · Electrical Eng. & Systems 2023-09-27 Obaidullah Rahman , Singanallur V. Venkatakrishnan , Luke Scime , Paul Brackman , Curtis Frederick , Ryan Dehoff , Vincent Paquit , Amirkoushyar Ziabari

Computed Tomography (CT) measures the attenuation coefficient of an object and converts the value assigned to each voxel into a CT number. In radiation therapy, CT number, which is directly proportional to the linear attenuation…

Medical Physics · Physics 2015-03-13 Dong Joo Rhee , Sung-woo Kim , Young Min Moon , Jung Ki Kim , Dong Hyeok Jeong

Denoising of images is a crucial preprocessing step in medical imaging, essential for improving diagnostic clarity. While deep learning methods offer state-of-the-art performance, their computational complexity and data requirements can be…

Statistical Mechanics · Physics 2025-10-01 M. Ali Saif , Bassam M. Mughalles , Ibrahim G. H. Loqman

Accurate lung nodule detection for computed tomography (CT) scan imagery is challenging in real-world settings due to the sparse occurrence of nodules and similarity to other anatomical structures. In a typical positive case, nodules may…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Hooman Ramezani , Dionne Aleman , Daniel Létourneau

Image denoising techniques are essential to reducing noise levels and enhancing diagnosis reliability in low-dose computed tomography (CT). Machine learning based denoising methods have shown great potential in removing the complex and…

Computer Vision and Pattern Recognition · Computer Science 2017-08-29 Dufan Wu , Kyungsang Kim , Georges El Fakhri , Quanzheng Li

Self-supervised image denoising techniques emerged as convenient methods that allow training denoising models without requiring ground-truth noise-free data. Existing methods usually optimize loss metrics that are calculated from multiple…

Monocular depth estimation is a challenging task in complex compositions depicting multiple objects of diverse scales. Albeit the recent great progress thanks to the deep convolutional neural networks (CNNs), the state-of-the-art monocular…

Computer Vision and Pattern Recognition · Computer Science 2017-08-09 Bo Li , Yuchao Dai , Mingyi He

Automatic lymph node (LN) segmentation and detection for cancer staging are critical. In clinical practice, computed tomography (CT) and positron emission tomography (PET) imaging detect abnormal LNs. Despite its low contrast and variety in…

Image and Video Processing · Electrical Eng. & Systems 2022-12-23 Al-Akhir Nayan , Boonserm Kijsirikul , Yuji Iwahori

Due to the energy-dependent nature of the attenuation coefficient and the polychromaticity of the X-ray source, beam hardening effect occurs when X-ray photons penetrate through an object, causing a nonlinear projection data. When a linear…

Medical Physics · Physics 2018-12-07 Wei Zhao , Dengwang Li , Kai Niu , Wenjian Qin , Hao Peng , Tianye Niu

Despite the indispensable role of X-ray computed tomography (CT) in diagnostic medicine field, the associated ionizing radiation is still a major concern considering that it may cause genetic and cancerous diseases. Decreasing the exposure…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Ti Bai , Dan Nguyen , Biling Wang , Steve Jiang

Purposes: This study aimed to develop a computed tomography (CT)-based multi-organ segmentation model for delineating organs-at-risk (OARs) in pediatric upper abdominal tumors and evaluate its robustness across multiple datasets. Materials…

Many renal cancers are incidentally found on non-contrast CT (NCCT) images. On contrast-enhanced CT (CECT) images, most kidney tumors, especially renal cancers, have different intensity values compared to normal tissues. However, on NCCT…

Image and Video Processing · Electrical Eng. & Systems 2023-12-11 Taro Hatsutani , Akimichi Ichinose , Keigo Nakamura , Yoshiro Kitamura