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Cancer is one of the leading causes of death globally, and early diagnosis is crucial for patient survival. Deep learning algorithms have great potential for automatic cancer analysis. Artificial intelligence has achieved high performance…

Image and Video Processing · Electrical Eng. & Systems 2024-04-16 Monika Górka , Daniel Jaworek , Marek Wodzinski

Cellular Electron Cryo-Tomography (CECT) is a powerful imaging technique for the 3D visualization of cellular structure and organization at submolecular resolution. It enables analyzing the native structures of macromolecular complexes and…

Quantitative Methods · Quantitative Biology 2018-05-16 Chang Liu , Xiangrui Zeng , Ruogu Lin , Xiaodan Liang , Zachary Freyberg , Eric Xing , Min Xu

Spectral CT has great potential for a variety of clinical applications due to the improved material discrimination with respect to conventional CT. Many clinical and preclinical spectral CT systems have two spectral channels for dual-energy…

Medical Physics · Physics 2020-10-17 Matthew Tivnan , Wenying Wang , J. Webster Stayman

Computed tomography (CT) is a widely used non-invasive diagnostic method in various fields, and recent advances in deep learning have led to significant progress in CT image reconstruction. However, the lack of large-scale, open-access…

Image and Video Processing · Electrical Eng. & Systems 2024-12-12 Maximilian B. Kiss , Ander Biguri , Zakhar Shumaylov , Ferdia Sherry , K. Joost Batenburg , Carola-Bibiane Schönlieb , Felix Lucka

In dual-energy computed tomography (DECT), low- and high- kVp data are collected often over a full-angular range (FAR) of $360^\circ$. While there exists strong interest in DECT with low- and high-kVp data acquired over limited-angular…

Medical Physics · Physics 2021-08-17 Buxin Chen , Zheng Zhang , Dan Xia , Emil Y. Sidky , Xiaochuan Pan

Purpose: To evaluate a proposed method to reconstruct CT numbers that accurately mimic conventional CT numbers from spectral CT data, as would have been produced by a conventional system without effects of beam hardening. Approach: We…

Medical Physics · Physics 2022-08-10 Fredrik Grönberg , Hans Bornefalk

Numerous dual-energy CT (DECT) techniques have been developed in the past few decades. Dual-energy CT (DECT) statistical iterative reconstruction (SIR) has demonstrated its potential for reducing noise and increasing accuracy. Our lab…

Image and Video Processing · Electrical Eng. & Systems 2023-02-02 Tao Ge , Maria Medrano , Rui Liao , David G. Politte , Jeffrey F. Williamson , Bruce R. Whiting , Joseph A. O'Sullivan

Computed tomography (CT) is routinely used for three-dimensional non-invasive imaging. Numerous data-driven image denoising algorithms were proposed to restore image quality in low-dose acquisitions. However, considerably less research…

Breast CT provides image volumes with isotropic resolution in high contrast, enabling detection of small calcification (down to a few hundred microns in size) and subtle density differences. Since breast is sensitive to x-ray radiation,…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Huidong Xie , Hongming Shan , Wenxiang Cong , Chi Liu , Xiaohua Zhang , Shaohua Liu , Ruola Ning , Ge Wang

Dual-energy imaging is a clinically well-established technique that offers several advantages over conventional X-ray imaging. By performing measurements with two distinct X-ray spectra, differences in energy-dependent attenuation are…

Low-dose computed tomography (CT) denoising algorithms aim to enable reduced patient dose in routine CT acquisitions while maintaining high image quality. Recently, deep learning~(DL)-based methods were introduced, outperforming…

Image and Video Processing · Electrical Eng. & Systems 2022-10-21 Fabian Wagner , Mareike Thies , Felix Denzinger , Mingxuan Gu , Mayank Patwari , Stefan Ploner , Noah Maul , Laura Pfaff , Yixing Huang , Andreas Maier

The manual ground truth of abdominal multi-organ is labor-intensive. In order to make full use of CT data, we developed a semi-supervised learning based dual-light UNet. In the training phase, it consists of two light UNets, which make full…

Image and Video Processing · Electrical Eng. & Systems 2022-09-23 Haoran Lai , Tao Wang , Shuoling Zhou

Manual or automatic delineation of the esophageal tumor in CT images is known to be very challenging. This is due to the low contrast between the tumor and adjacent tissues, the anatomical variation of the esophagus, as well as the…

Cone Beam Computed Tomography(CBCT) is a now known method to conduct CT imaging. Especially, The Low Dose CT imaging is one of possible options to protect organs of patients when conducting CT imaging. Therefore Low Dose CT imaging can be…

Computer Vision and Pattern Recognition · Computer Science 2021-04-05 Wooram Kang , Mayank Patwari

Increasing use of CT in modern medical practice has raised concerns over associated radiation dose. Reduction of radiation dose associated with CT can increase noise and artifacts, which can adversely affect diagnostic confidence. Denoising…

Computer Vision and Pattern Recognition · Computer Science 2017-02-24 Qingsong Yang , Pingkun Yan , Mannudeep K. Kalra , Ge Wang

Background: Limited-angle (LA) dual-energy (DE) cone-beam CT (CBCT) is considered as a potential solution to achieve fast and low-dose DE imaging on current CBCT scanners without hardware modification. However, its clinical implementations…

Multi-Energy Computed Tomography (ME-CT) is a medical imaging modality aiming to reconstruct the spatial density of materials from the attenuation properties of probing x-rays. For each line in two- or three-dimensional space, ME-CT…

Numerical Analysis · Mathematics 2020-06-24 Guillaume Bal , Fatma Terzioglu

This study proposes a novel imaging and reconstruction framework for dual-energy cone-beam CT (DECBCT) using only two orthogonal X-ray projections at different energy levels (2V-DECBCT). The goal is to enable fast and low-dose DE volumetric…

Medical Physics · Physics 2025-04-18 Junbo Peng , Tonghe Wang , Shaoyan Pan , Xiaofeng Yang

X-ray computed tomography (XCT) has become a reliable metrology tool for measuring internal flaws and other microstructural features in engineering materials. However, tracking of material points to measure three-dimensional (3D)…

Materials Science · Physics 2023-04-13 Zifan Wang , Akshay Joshi , Angkur Jyoti Dipanka Shaikeea , Vikram Susdhir Deshpande

Material decomposition for imaging multiple contrast agents in a single acquisition has been made possible by spectral CT: a modality which incorporates multiple photon energy spectral sensitivities into a single data collection. This work…

Medical Physics · Physics 2020-08-11 Matthew Tivnan , Steven Tilley , J. Webster Stayman
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