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The outcome of vertebroplasty is hard to predict due to its dependence on complex factors like bone cement and marrow rheologies. Cement leakage could occur if the procedure is done incorrectly, potentially causing adverse complications. A…

The failure of heterogeneous materials with microstructures is a complex process of damage nucleation, growth and localisation. This process spans multiple length scales and is challenging to simulate numerically due to its high…

Materials Science · Physics 2023-05-24 Philip P. Müller , Falk K. Wittel , David S. Kammer

The main goal of this work is to clarify and quantify, by means of mathematical analysis, the role of structural viscoelasticity in the biomechanical response of deformable porous media with incompressible constituents to sudden changes in…

Analysis of PDEs · Mathematics 2017-10-03 Maurizio Verri , Giovanna Guidoboni , Lorena Bociu , Riccardo Sacco

While crack nucleation and propagation in the brittle or quasi-brittle regime can be predicted via variational or material-force-based phase field fracture models, these models often assume that the underlying elastic response of the…

Computational Engineering, Finance, and Science · Computer Science 2020-08-13 Hyoung Suk Suh , WaiChing Sun , Devin O'Connor

In medicolegal situations, the consequences of a stabbing incident are described in terms that are qualitative without being quantitative. Here, the mechanical variables involved in knife-tissue penetration events are used to determine the…

Classical Physics · Physics 2008-11-25 Michael D. Gilchrist , Stephen Keenan , Michael Curtis , Mary Cassidy , Greg Byrne , Michel Destrade

We argue that nucleation of brittle cracks in initially flawless soft elastic solids is preceded by a nonlinear elastic instability, which cannot be captured without accounting for geometrical precise description of finite elastic…

Soft Condensed Matter · Physics 2024-06-17 D. Riccobelli , P. Ciarletta , G. Vitale , C. Maurini , L. Truskinovsky

In the fiber melt spinning of semi-crystalline polymers, the degree of crystallization can be non-homogeneous over the cross-section of the fiber, affecting the properties of the end product. For simulation-based process design, the…

Fluid Dynamics · Physics 2024-07-12 Manuel Ettmüller , Walter Arne , Nicole Marheineke , Raimund Wegener

This study presents the formulation, the numerical solution, and the validation of a theoretical framework based on the concept of variable-order mechanics and capable of modeling dynamic fracture in brittle and quasi-brittle solids. More…

Materials Science · Physics 2020-08-26 Sansit Patnaik , Fabio Semperlotti

We study what is clearly one of the most common modes of deformation found in nature, science and engineering, namely the large elastic bending of curved structures, as well as its inverse, unbending, which can be brought beyond complete…

Soft Condensed Matter · Physics 2018-06-11 Taisiya Sigaeva , Robert Mangan , Luigi Vergori , Michel Destrade , Les Sudak

Inelastic mechanical responses in solids, such as plasticity, damage and crack initiation, are typically modeled in constitutive ways that display microstructural and loading dependence. Nevertheless, {linear} elasticity at infinitesimal…

Applied Physics · Physics 2019-12-23 Stefanos Papanikolaou

Dental implant stability influences the decision on the determination of the duration between implant insertion and loading, This work investigates the resonant frequency analysis by means of a numerical model. The investigation is done…

Medical Physics · Physics 2019-05-20 D Rittel , A Dorogoy , G. Haiat , K Shemtov-Yona

In this paper we propose an ecological resilience point of view on cancer. This view is based on the analysis of a simple ODE model for the interactions between cancer and normal cells. The model presents two regimes for tumor growth. In…

Populations and Evolution · Quantitative Biology 2016-09-01 Artur C. Fassoni , Hyun M. Yang

This paper develops a general data-driven approach to stochastic elastoplastic modelling that leverages atomistic simulation data directly rather than by fitting parameters. The approach is developed in the context of metallic glasses,…

Statistical Mechanics · Physics 2024-10-02 Bin Xu , Zhao Wu , Jiayin Lu , Michael D. Shields , Chris H. Rycroft , Franz Bamer , Michael L. Falk

Connecting cell behavior to tissue shape and mechanics is a key challenge in the physics of morphogenesis. Cytoskeletal turnover precludes a fixed reference state, and tensions are actively generated independently of strain; so conventional…

Soft Condensed Matter · Physics 2026-05-28 Nikolas H. Claussen , Fridtjof Brauns , Boris I. Shraiman

A model for morphoelastic growth, that is, growth influenced by elastic stress, driven by the absorption of nutrients is considered. The model features a multiplicative decomposition of the deformation gradient into an elastic contribution…

Analysis of PDEs · Mathematics 2026-05-05 Helmut Abels , Julian Blawid , Georg Dolzmann

Mathematical models for physiological processes aid qualitative understanding of the impact of various parameters on the underlying process. We analyse two such models for human physiological processes: the Mackey-Glass and the Lasota…

Systems and Control · Computer Science 2018-10-12 Sreelakshmi Manjunath , Gopal Krishna Kamath , Gaurav Raina

Skin contraction is an important biophysical process that takes place during and after the recovery of deep tissue injury. This process is mainly caused by fibroblasts (skin cells) and myofibroblasts (differentiated fibroblasts) that exert…

Numerical Analysis · Mathematics 2021-05-20 Q. Peng , F. J. Vermolen

Statistical models provide a powerful and useful class of approximations for calculating reaction rates by bypassing the need for detailed, and often difficult, dynamical considerations. Such approaches invariably invoke specific…

Chemical Physics · Physics 2020-04-01 Sourav Karmakar , Pankaj Kumar Yadav , Srihari Keshavamurthy

Developing a macroscopic theory of elasto-plasticity in amorphous solids calls for (i) identifying the relevant macro state-variables and (ii) discriminating the different time-scales which characterize these variables. In current theories…

Statistical Mechanics · Physics 2009-11-25 Laurent Boue , Peter Harrowell , Smarajit Karmakar , Edan Lerner , Itamar Procaccia , Ido Regev , Jacques Zylberg

Failure in brittle materials under dynamic loading conditions is a result of the propagation and coalescence of microcracks. Simulating this mechanism at the continuum level is computationally expensive or, in some cases, intractable. The…