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In processes such as embryo shaping, wound healing, and malignant cell invasion, epithelial cells transition between dispersed phases, where the cells move independently, and condensed phases, where they aggregate and deform to close gaps,…

Soft Condensed Matter · Physics 2024-09-25 Anshuman Pasupalak , Zeng Wu , Massimo Pica Ciamarra

Collagen fibers, an important component of the extracellular matrix (ECM), can both inhibit and promote cellular migration. {\it In-vitro} studies have revealed that the fibers' orientations are crucial to cellular invasion, while {\it…

Cell Behavior · Quantitative Biology 2019-07-01 Youness Azimzade , Abbas Ali Saberi , Muhammad Sahimi

Motile biological cells in tissue often display the phenomenon of durotaxis, i.e. they tend to move towards stiffer parts of substrate tissue. The mechanism for this behavior is not completely understood. We consider simplified models for…

Biological Physics · Physics 2019-01-03 Charles R. Doering , Xiaoming Mao , Leonard M. Sander

In vitro cell biology experiments are routinely used to characterize cell migration properties under various experimental conditions. These experiments can be interpreted using lattice-based random walk models to provide insight into…

Applied Physics · Physics 2024-06-25 Yihan Liu , David J Warne , Matthew J Simpson

Cell movement has essential functions in development, immunity and cancer. Various cell migration patterns have been reported and a general rule has recently emerged, the so-called UCSP (Universal Coupling between cell Speed and cell…

Analysis of PDEs · Mathematics 2019-12-17 Christèle Etchegaray , Nicolas Meunier , Raphael Voituriez

Random walks are studied on disordered cellular networks in 2-and 3-dimensional spaces with arbitrary curvature. The coefficients of the evolution equation are calculated in term of the structural properties of the cellular system. The…

Disordered Systems and Neural Networks · Physics 2009-10-28 Tomaso Aste

T cells undergo large shape changes (morphodynamics) when migrating. While progress has been made elucidating the molecular basis of cell migration, statistical characterization of morphodynamics and migration has been limited, particularly…

Cell Behavior · Quantitative Biology 2024-08-09 Yeeren I. Low

Cells use temporal dynamical patterns to transmit information via signaling pathways. As optimality with respect to the environment plays a fundamental role in biological systems, organisms have evolved optimal ways to transmit information.…

Biological Physics · Physics 2016-12-21 Yoshihiko Hasegawa

When analyzing the individual positional dynamics of an ensemble of moving objects, the extracted parameters that characterize the motion of individual objects, such as the mean-squared instantaneous velocity or the diffusivity, exhibit a…

Cell migration plays a fundamental role in numerous physiological processes, including embryonic development, wound healing, and cancer metastasis. While cell-cell adhesion is known to regulate motion by shaping cell morphology and…

Biological Physics · Physics 2026-03-09 Anh Q. Nguyen , Pradip K. Bera , Jacob Notbohm , Dapeng Bi

Diverse organisms exploit the geomagnetic field (GMF) for migration. Migrating birds employ an intrinsically quantum mechanical mechanism for detecting the geomagnetic field: absorption of a blue photon generates a radical pair whose two…

In the absence of environmental cues, a migrating cell performs an isotropic random motion. Recently, the breaking of this isotropy has been observed when cells move in the presence of asymmetric adhesive patterns. However, up to now the…

Soft Condensed Matter · Physics 2015-06-17 M. Le Berre , Yan-Jun Liu , J. Hu , P. Maiuri , O. Bénichou , R. Voituriez , Y. Chen , M. Piel

We present a new wavelet based method for the denoising of {\it event related potentials} ERPs), employing techniques recently developed for the paradigm of deterministic chaotic systems. The denoising scheme has been constructed to be…

Data Analysis, Statistics and Probability · Physics 2009-11-06 A. Effern , K. Lehnertz , T. Schreiber , T. Grunwald , P. David , C. E. Elger

The wavelet transform has been used for numerous studies in astrophysics, including signal--noise periodicity and decomposition as well as the signature of differential rotation in stellar light curves. In the present work, we apply the…

Solar and Stellar Astrophysics · Physics 2010-09-28 D. B. de Freitas , I. de C. Leão , B. L. Canto Martins , J. R. De Medeiros

The jets of blazars are renowned for their multi-wavelength flares and rapid extreme variability; however, there are still some important unanswered questions about the physical processes responsible for these spectral and temporal changes…

High Energy Astrophysical Phenomena · Physics 2020-10-30 Y. G. Zheng , S. J. Kang , C. Y. Yang , J. M. Bai

Experimentally observed networks of interacting dynamical systems are inferred from recorded multivariate time series by evaluating a statistical measure of dependence, usually the cross-correlation coefficient, or mutual information. These…

Data Analysis, Statistics and Probability · Physics 2017-07-03 Milan Palus

Transient muscle movements influence the temporal structure of myoelectric signal patterns, often leading to unstable prediction behavior from movement-pattern classification methods. We show that temporal convolutional network sequential…

Computer Vision and Pattern Recognition · Computer Science 2019-09-02 Joseph L. Betthauser , John T. Krall , Rahul R. Kaliki , Matthew S. Fifer , Nitish V. Thakor

The response of cell populations to external stimuli plays a central role in biological mechanical processes such as epithelial wound healing and developmental morphogenesis. Wave-like propagation of a signal of ERK MAP kinase has been…

We propose a first-principles time-dependent density functional theoretical (TDDFT) approach in momentum (P) space for quantitative study of electron transport in molecular devices under arbitrary biases. In this approach, the basic…

Mesoscale and Nanoscale Physics · Physics 2009-02-10 Zhongyuan Zhou , Shih-I Chu

Cancer cells exhibit increased motility and proliferation, which are instrumental in the formation of tumours and metastases. These pathological changes can be traced back to malfunctions of cellular signalling pathways, and calcium…

Cell Behavior · Quantitative Biology 2020-03-03 Katerina Kaouri , Vasiliki Bitsouni , Andreas Buttenschön , Rüdiger Thul