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We introduce an adjoint-based aerodynamic shape optimization framework that integrates a diffusion model trained on existing designs to learn a smooth manifold of aerodynamically viable shapes. This manifold is enforced as an equality…

Computational Engineering, Finance, and Science · Computer Science 2025-08-01 Long Chen , Emre Oezkaya , Jan Rottmayer , Nicolas R. Gauger , Zebang Shen , Yinyu Ye

Current deep learning-based manifold learning algorithms such as the variational autoencoder (VAE) require fully sampled data to learn the probability density of real-world datasets. Once learned, the density can be used for a variety of…

Image and Video Processing · Electrical Eng. & Systems 2021-12-13 Qing Zou , Abdul Haseeb Ahmed , Prashant Nagpal , Sarv Priya , Rolf Schulte , Mathews Jacob

Background and Purpose: Our purpose was to develop a deep learning angiography (DLA) method to generate 3D cerebral angiograms from a single contrast-enhanced acquisition. Material and Methods: Under an approved IRB protocol 105 3D-DSA…

Image and Video Processing · Electrical Eng. & Systems 2018-01-30 Juan C. Montoya , Yinsheng Li , Charles Strother , Guang-Hong Chen

In addition to its public health crisis, COVID-19 pandemic has led to the shutdown and closure of workplaces with an estimated total cost of more than $16 trillion. Given the long hours an average person spends in buildings and indoor…

Systems and Control · Electrical Eng. & Systems 2022-12-29 Ashkan Haji Hosseinloo , Saleh Nabi , Anette Hosoi , Munther A. Dahleh

Airborne pandemics have caused millions of deaths worldwide, large-scale economic losses, and catastrophic sociological shifts in human history. Researchers have developed multiple mathematical models and computational frameworks to…

Information Retrieval · Computer Science 2024-06-18 Teddy Lazebnik , Ariel Alexi

Interstitial lung diseases are a large group of heterogeneous diseases characterized by different degrees of alveolitis and pulmonary fibrosis. Accurately diagnosing these diseases has significant guiding value for formulating treatment…

Image and Video Processing · Electrical Eng. & Systems 2022-06-22 Huafeng Hu , Ruijie Ye , Jeyarajan Thiyagalingam , Frans Coenen , Jionglong Su

Changes in cardiovascular hemodynamics are closely related to the development of aortic regurgitation, a type of valvular heart disease. Metrics derived from blood flows are used to indicate aortic regurgitation onset and evaluate its…

Computer Vision and Pattern Recognition · Computer Science 2022-04-07 Derek Long , Cameron McMurdo , Edward Ferdian , Charlene A. Mauger , David Marlevi , Alistair A. Young , Martyn P. Nash

The study focuses on the wind loads acting on the standard Commonwealth Advisory Aeronautical Council (CAARC) building model. Numerical modeling has been used instead of employing wind tunnel experiments due to the requirement of high…

Fluid Dynamics · Physics 2022-02-16 V. A. U. De Alwis , P. H. T. D. Weerarathne , K. K. Wijesundara

Clinical decision support systems (CDSS) will play an in-creasing role in improving the quality of medical care for critically ill patients. However, due to limitations in current informatics infrastructure, CDSS do not always have…

Machine Learning · Computer Science 2019-05-01 Gregory B. Rehm , Brooks T. Kuhn , Jimmy Nguyen , Nicholas R. Anderson , Chen-Nee Chuah , Jason Y. Adams

Focal arrhythmias, which arise from delayed afterdepolarizations (DADs), are observed in various pathophysiological heart conditions; these can lead to sudden cardiac death. A clear understanding of the electrophysiological factors of…

Tissues and Organs · Quantitative Biology 2023-07-20 Navneet Roshan , Rahul Pandit

Mathematical models and numerical simulations are widely used in the field of hemodynamics, representing a valuable resource to better understand physiological and pathological processes. The theory behind the phenomenon is closely related…

Fluid Dynamics · Physics 2021-06-15 Giulia Bertaglia , Valerio Caleffi , Alessandro Valiani

In the field of cardio-thoracic surgery, valve function is monitored over time after surgery. The motivation for our research comes from a study which includes patients who received a human tissue valve in the aortic position. These…

We develop data-driven dynamical models of the nonlinear aeroelastic effects on a long-span suspension bridge from sparse, noisy sensor measurements which monitor the bridge. Using the {\em sparse identification of nonlinear dynamics}…

Pattern Formation and Solitons · Physics 2018-09-18 Shanwu Li , Eurika Kaiser , Shujin Laima , Hui Li , Steven L. Brunton , J. Nathan Kutz

Developing safety policies to protect large groups of individuals working in indoor environments from disease spread is an important and challenging task. To address this issue, we investigate the scenario of workers becoming infected by a…

Computational Engineering, Finance, and Science · Computer Science 2025-01-08 Krzysztof Domino , Arkadiusz Sochan , Jarosław Adam Miszczak

Ducted fan lift systems (DFLSs) powered by two-stroke aviation piston engines present a challenging control problem due to their complex multivariable dynamics. Current controllers for these systems typically rely on proportional-integral…

Systems and Control · Electrical Eng. & Systems 2023-09-25 Hanjie Jiang , Ye Zhou , Hann Woei Ho , Wenjie Hu

Slender marine structures such as deep-water marine risers are subjected to currents and will normally experience Vortex Induced Vibrations (VIV), which can cause fast accumulation of fatigue damage. The ocean current is often…

Data Analysis, Statistics and Probability · Physics 2019-06-27 Signe Riemer-Sørensen , Jie Wu , Halvor Lie , Svein Sævik , Sang-Woo Kim

Lung cancer has the highest mortality rate of deadly cancers in the world. Early detection is essential to treatment of lung cancer. However, detection and accurate diagnosis of pulmonary nodules depend heavily on the experiences of…

Image and Video Processing · Electrical Eng. & Systems 2022-04-12 Chenglong Wang , Yun Liu , Fen Wang , Chengxiu Zhang , Yida Wang , Mei Yuan , Guang Yang

Autism spectrum disorder (ASD) is a complex neurodevelopmental syndrome. Early diagnosis and precise treatment are essential for ASD patients. Although researchers have built many analytical models, there has been limited progress in…

Neurons and Cognition · Quantitative Biology 2018-10-30 Juntang Zhuang , Nicha C. Dvornek , Xiaoxiao Li , Pamela Ventola , James S. Duncan

Objective: When patients develop acute respiratory failure, accurately identifying the underlying etiology is essential for determining the best treatment. However, differentiating between common medical diagnoses can be challenging in…

Machine Learning · Computer Science 2022-04-21 Sarah Jabbour , David Fouhey , Ella Kazerooni , Jenna Wiens , Michael W Sjoding

This study presents a compact data-driven Reynolds-averaged Navier-Stokes (RANS) model for wind turbine wake prediction, built as an enhancement of the standard \(k\)-\(\varepsilon\) formulation. Several candidate models were discovered…

Fluid Dynamics · Physics 2025-12-09 Kherlen Jigjid , Ali Eidi , Nguyen Anh Khoa Doan , Richard P. Dwight