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Deep learning has shown strong performance in time series forecasting tasks. However, issues such as missing values and anomalies in sequential data hinder its further development in prediction tasks. Previous research has primarily focused…

Machine Learning · Computer Science 2025-12-17 Hua Wang , Jinghao Lu , Fan Zhang

The success of deep learning has been witnessed as a promising technique for computer-aided biomedical image analysis, due to end-to-end learning framework and availability of large-scale labelled samples. However, in many cases of…

Computer Vision and Pattern Recognition · Computer Science 2019-08-02 Pengyi Zhang , Yunxin Zhong , Yulin Deng , Xiaoying Tang , Xiaoqiong Li

Recent advances in deep learning architectures for sequence modeling have not fully transferred to tasks handling time-series from electronic health records. In particular, in problems related to the Intensive Care Unit (ICU), the…

Machine Learning · Computer Science 2024-02-07 Rita Kuznetsova , Alizée Pace , Manuel Burger , Hugo Yèche , Gunnar Rätsch

Measuring uncertainties in the output of a deep learning method is useful in several ways, such as in assisting with interpretation of the outputs, helping build confidence with end users, and for improving the training and performance of…

Machine Learning · Computer Science 2022-09-20 Luke Whitbread , Mark Jenkinson

For over two decades, detecting rare events has been a challenging task among researchers in the data mining and machine learning domain. Real-life problems inspire researchers to navigate and further improve data processing and algorithmic…

Machine Learning · Computer Science 2025-09-09 Elaheh Jafarigol , Theodore Trafalis , Neshat Mohammadi

Intelligent diagnosis method based on data-driven and deep learning is an attractive and meaningful field in recent years. However, in practical application scenarios, the imbalance of time-series fault is an urgent problem to be solved.…

Machine Learning · Computer Science 2021-07-15 Xingtai Gui , Jiyang Zhang

Empirically observed time series in physics, biology, or medicine, are commonly generated by some underlying dynamical system (DS) which is the target of scientific interest. There is an increasing interest to harvest machine learning…

Machine Learning · Computer Science 2022-07-07 Daniel Kramer , Philine Lou Bommer , Carlo Tombolini , Georgia Koppe , Daniel Durstewitz

State-space models (SSMs) offer a powerful framework for dynamical system analysis, wherein the temporal dynamics of the system are assumed to be captured through the evolution of the latent states, which govern the values of the…

Machine Learning · Statistics 2024-12-17 Jiahe Lin , George Michailidis

Analysis of longitudinal Electronic Health Record (EHR) data is an important goal for precision medicine. Difficulty in applying Machine Learning (ML) methods, either predictive or unsupervised, stems in part from the heterogeneity and…

Quantitative Methods · Quantitative Biology 2022-04-18 Alan D. Kaplan , Uttara Tipnis , Jean C. Beckham , Nathan A. Kimbrel , David W. Oslin , Benjamin H. McMahon

Distributed machine learning (ML) can bring more computational resources to bear than single-machine learning, thus enabling reductions in training time. Distributed learning partitions models and data over many machines, allowing model and…

Machine Learning · Computer Science 2022-04-20 Binhang Yuan , Cameron R. Wolfe , Chen Dun , Yuxin Tang , Anastasios Kyrillidis , Christopher M. Jermaine

Deep neural networks (DNNs) have made a revolution in numerous fields during the last decade. However, in tasks with high safety requirements, such as medical or autonomous driving applications, providing an assessment of the models…

Machine Learning · Computer Science 2020-11-20 Omer Achrack , Raizy Kellerman , Ouriel Barzilay

Interpretable classification of time series presents significant challenges in high dimensions. Traditional feature selection methods in the frequency domain often assume sparsity in spectral density matrices (SDMs) or their inverses, which…

Machine Learning · Statistics 2024-08-19 Sarbojit Roy , Malik Shahid Sultan , Hernando Ombao

In several practical applications, particularly healthcare, clinical data of each patient is individually recorded in a database at irregular intervals as required. This causes a sparse and irregularly sampled time series, which makes it…

Machine Learning · Computer Science 2025-04-09 Mincheol Kim , Soo-Yong Shin

Treatment of acute ischemic strokes (AIS) is largely contingent upon the time since stroke onset (TSS). However, TSS may not be readily available in up to 25% of patients with unwitnessed AIS. Current clinical guidelines for patients with…

Image and Video Processing · Electrical Eng. & Systems 2021-05-03 Haoyue Zhang , Jennifer S Polson , Kambiz Nael , Noriko Salamon , Bryan Yoo , Suzie El-Saden , Fabien Scalzo , William Speier , Corey W Arnold

Spatially resolved transcriptomics (SRT) has evolved rapidly through various technologies, enabling scientists to investigate both morphological contexts and gene expression profiling at single-cell resolution in parallel. SRT data are…

Handling anomalies is a critical preprocessing step in multivariate time series prediction. However, existing approaches that separate anomaly preprocessing from model training for multivariate time series prediction encounter significant…

Machine Learning · Computer Science 2025-01-15 Yuanyuan Liang , Tianhao Zhang , Tingyu Xie

Healthcare data frequently contain a substantial proportion of missing values, necessitating effective time series imputation to support downstream disease diagnosis tasks. However, existing imputation methods focus on discrete data points…

Machine Learning · Computer Science 2025-05-19 Mengxuan Li , Ke Liu , Jialong Guo , Jiajun Bu , Hongwei Wang , Haishuai Wang

Irregularly sampled multivariate time series are ubiquitous in various fields, particularly in healthcare, and exhibit two key characteristics: intra-series irregularity and inter-series discrepancy. Intra-series irregularity refers to the…

Machine Learning · Computer Science 2023-06-19 Jiawen Zhang , Shun Zheng , Wei Cao , Jiang Bian , Jia Li

Hybrid methods have been shown to outperform pure statistical and pure deep learning methods at both forecasting tasks, and at quantifying the uncertainty associated with those forecasts (prediction intervals). One example is Multivariate…

Machine Learning · Computer Science 2022-02-28 Thabang Mathonsi , Terence L van Zyl

Errors are prevalent in time series data, especially in the industrial field. Data with errors could not be stored in the database, which results in the loss of data assets. Handling the dirty data in time series is non-trivial, when given…

Databases · Computer Science 2020-06-09 Xi Wang , Chen Wang