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Individualized treatment recommendation (ITR) is an important analytic framework for precision medicine. The goal is to assign proper treatments to patients based on their individual characteristics. From the machine learning perspective,…
To rank nodes in quasi-hierarchical networks of social nature, it is necessary to carry out a detailed analysis of the network and evaluate the results obtained according to all the given criteria and identify the most influential nodes.…
Effective therapy of complex diseases requires control of highly non-linear complex networks that remain incompletely characterized. In particular, drug intervention can be seen as control of signaling in cellular networks. Identification…
The last decade has seen a revolution in the theory and application of machine learning and pattern recognition. Through these advancements, variable ranking has emerged as an active and growing research area and it is now beginning to be…
The ongoing pandemic has highlighted the importance of reliable and efficient clinical trials in healthcare. Trial sites, where the trials are conducted, are chosen mainly based on feasibility in terms of medical expertise and access to a…
The simultaneous application of multiple treatments is increasingly common in many fields, such as healthcare and marketing. In such scenarios, it is important to estimate the single treatment effects and the interaction treatment effects…
Optimal curing strategy of suppressing competing epidemics spreading over complex networks is a critical issue. In this paper, we first establish a framework to capture the coupling between two epidemics, and then analyze the system's…
Ranking models are typically designed to provide rankings that optimize some measure of immediate utility to the users. As a result, they have been unable to anticipate an increasing number of undesirable long-term consequences of their…
Over the past decade, the field of machine learning has experienced remarkable advancements. While image recognition systems have achieved impressive levels of accuracy, they continue to rely on extensive training datasets. Additionally, a…
Not only does mobile health technology enable researchers to track changes in multiple longitudinal outcomes of interest and to record the occurrence of health-related events over time, but it also allows for the delivery of repeated…
Understanding how the causal effect of a treatment evolves over time, including the potential for waning, is important for informed decisions on treatment discontinuation or repetition. For example, waning vaccine protection influences…
Many models in mathematical epidemiology are developed with the aim to provide a framework for parameter estimation and then prediction. It is well-known that parameters are not always uniquely identifiable. In this paper we consider…
Estimation of conditional average treatment effects (CATEs) plays an essential role in modern medicine by informing treatment decision-making at a patient level. Several metalearners have been proposed recently to estimate CATEs in an…
The aim of clinical effectiveness research using repositories of electronic health records is to identify what health interventions 'work best' in real-world settings. Since there are several reasons why the net benefit of intervention may…
Purpose: To identify the most informative methods for reporting results of treatment planning comparisons. Methods: Seven papers from the past year of International Journal of Radiation Oncology Biology Physics reported on comparisons of…
The feedback that users provide through their choices (e.g., clicks, purchases) is one of the most common types of data readily available for training search and recommendation algorithms. However, myopically training systems based on…
Machine Learning (ML) algorithms are vital for supporting clinical decision-making in biomedical informatics. However, their predictive performance can vary across demographic groups, often due to the underrepresentation of historically…
This paper investigates how certain relationship between observed and counterfactual distributions serves as an identifying condition for treatment effects when the treatment is endogenous, and shows that this condition holds in a range of…
Hierarchical multi-label classification (HMC) has gained considerable attention in recent decades. A seminal line of HMC research addresses the problem in two stages: first, training individual classifiers for each class, then integrating…
Annually, at the Conference of Machine Translation (WMT), the Metrics Shared Task organizers conduct the meta-evaluation of Machine Translation (MT) metrics, ranking them according to their correlation with human judgments. Their results…