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The quasi-deterministic limit of the generic extinction transition is considered within the framework of standard epidemiological models. The susceptible-infected-susceptible (SIS) model is known to exhibit a transition from extinction to…

Statistical Mechanics · Physics 2009-11-13 David A. Kessler , Nadav M. Shnerb

We propose a new model that describes the dynamics of epidemic spreading on connected graphs. Our model consists in a PDE-ODE system where at each vertex of the graph we have a standard SIR model and connexions between vertices are given by…

Analysis of PDEs · Mathematics 2020-11-25 Christophe Besse , Grégory Faye

The transmission dynamics of some infectious diseases is related to the contact structure between individuals in a network. We used five algorithms to generate contact networks with different topological structure but with the same…

Populations and Evolution · Quantitative Biology 2013-08-28 Raul Ossada , José H. H. Grisi-Filho , Fernando Ferreira , Marcos Amaku

We propose an epidemic model for the spread of vector-borne diseases. The model, which is built extending the classical susceptible-infected-susceptible model, accounts for two populations -- humans and vectors -- and for cross-contagion…

Systems and Control · Electrical Eng. & Systems 2025-10-21 Lorenzo Zino , Alessandro Casu , Alessandro Rizzo

Risk-driven behavior provides a feedback mechanism through which individuals both shape and are collectively affected by an epidemic. We introduce a general and flexible compartmental model to study the effect of heterogeneity in the…

We consider multiple diseases spreading in a static Configuration Model network. We make standard assumptions that infection transmits from neighbor to neighbor at a disease-specific rate and infected individuals recover at a…

Populations and Evolution · Quantitative Biology 2015-06-11 Joel C. Miller

Seasonal variations in the incidence of infectious diseases are a well-established phenomenon, driven by factors such as climate changes, social behaviors, and ecological interactions that influence host susceptibility and transmission…

Populations and Evolution · Quantitative Biology 2024-10-23 Mahmudul Bari Hridoy

We study an infection-age structured epidemic model in which both the infectivity and the rate of loss of immunity depend on the time-since-infection. The model can be equivalently viewed as a nonlinear renewal equation for the incidence of…

Dynamical Systems · Mathematics 2025-11-13 Francesca Scarabel , Harry Coldwell , Tyler Cassidy

We study how the interplay between the memory immune response and pathogen mutation affects epidemic dynamics in two related models. The first explicitly models pathogen mutation and individual memory immune responses, with contacted…

Chaotic Dynamics · Physics 2009-11-07 Michelle Girvan , Duncan S. Callaway , M. E. J. Newman , Steven H. Strogatz

Early estimates of the transmission potential of emerging and re-emerging infections are increasingly used to inform public health authorities on the level of risk posed by outbreaks. Existing methods to estimate the reproduction number…

Quantitative Methods · Quantitative Biology 2016-10-10 Gerardo Chowell , Cécile Viboud , Lone Simonsen , Seyed Moghadas

During pandemic events, strategies such as social distancing can be fundamental to curb viral spreading. Such actions can reduce the number of simultaneous infections and mitigate the disease spreading, which is relevant to the risk of a…

Physics and Society · Physics 2021-02-24 Marco A. Amaral , Marcelo M. de Oliveira , Marco A. Javarone

We introduce an extension to Kermack and McKendrick's classic susceptible-infected-recovered (SIR) model in epidemiology, whose underlying mechanism of infection consists of individuals attending randomly generated social gatherings. This…

Probability · Mathematics 2024-05-08 Roberto Cortez

Chronic viral infections can persist in an infected person for decades. From the perspective of the virus, a single infection can span thousands of generations, leading to a highly diverse population of viruses with its own complex…

Populations and Evolution · Quantitative Biology 2023-05-30 Dmitry Gromov , Ethan O. Romero-Severson

The population is composed of individuals characterised by their genetic strings, phenotypes and ages. We discuss the influence of probabilities of survival of the individuals on the dynamics and phenotypic variability of the population. We…

Biological Physics · Physics 2009-11-10 Iwona Mroz

We propose an extension of the classical susceptible infectious recovered (SIR) model that incorporates the effects of spatial propagation of an epidemic through a small number of additional compartments. The model is designed to capture…

Numerical Analysis · Mathematics 2026-03-02 M. Soledad Aronna , Mariana Bergonzi , Ernesto Kofman

We study the qualitative properties of a spatial diffusive heterogeneous SIR model, that appears in mathematical epidemiology to describe the spread of an infectious disease in a population. The model we consider consists in a system of…

Analysis of PDEs · Mathematics 2020-05-15 Romain Ducasse

The Susceptible-Infected-Susceptible model is a canonical model for emerging disease outbreaks. Such outbreaks are naturally modeled as taking place on networks. A theoretical challenge in network epidemiology is the dynamic correlations…

Physics and Society · Physics 2016-06-29 Chao-Ran Cai , Zhi-Xi Wu , Michael Z. Q. Chen , Petter Holme , Jian-Yue Guan

Numerous elements drive the spread of infectious diseases in complex real-world networks. Of particular interest is social behaviors that evolve in tandem with the spread of disease. Moreover, recent studies highlight the importance of…

Systems and Control · Electrical Eng. & Systems 2025-10-03 Benjamin Catalano , Keith Paarporn , Sebin Gracy

Existing studies comparing individual-based models of growing cell populations and their continuum counterparts have mainly focused on homogeneous populations, in which all cells have the same phenotypic characteristics. However,…

Populations and Evolution · Quantitative Biology 2022-06-06 Fiona R Macfarlane , Xinran Ruan , Tommaso Lorenzi

An actively controlled Susceptible-Infected-Susceptible (actSIS) contagion model is presented for studying epidemic dynamics with continuous-time feedback control of infection rates. Our work is inspired by the observation that epidemics…

Physics and Society · Physics 2020-07-06 Yunxiu Zhou , Simon A. Levin , Naomi E. Leonard