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Focal cortical dysplasia (FCD) is a leading cause of drug-resistant focal epilepsy, which can be cured by surgery. These lesions are extremely subtle and often missed even by expert neuroradiologists. "Ground truth" manual lesion masks are…

Image and Video Processing · Electrical Eng. & Systems 2023-06-06 Hannah Spitzer , Mathilde Ripart , Abdulah Fawaz , Logan Z. J. Williams , MELD project , Emma Robinson , Juan Eugenio Iglesias , Sophie Adler , Konrad Wagstyl

Focal cortical dysplasia (FCD) type II is a major cause of drug-resistant epilepsy, often curable only by surgery. Despite its clinical importance, the diagnosis of FCD is very difficult in MRI because of subtle abnormalities, leading to…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Lorenzo Lasagni , Antonio Ciccarone , Renzo Guerrini , Matteo Lenge , Ludovico D'incerti

Focal Cortical Dysplasia (FCD) is a primary cause of drug-resistant epilepsy and is difficult to detect in brain {magnetic resonance imaging} (MRI) due to the subtle and small-scale nature of its lesions. Accurate segmentation of FCD…

Image and Video Processing · Electrical Eng. & Systems 2025-10-09 Mehdi Rabiee , Sergio Greco , Reza Shahbazian , Irina Trubitsyna

Focal cortical dysplasias (FCDs) are the most common cause of treatment resistant epilepsy affecting the pediatric population. Most individuals with FCD have seizure onset during the first five years of life and the majority will have…

Neurons and Cognition · Quantitative Biology 2022-01-28 Garrett Garner , Daniel Streetman , Joshua Fricker , Neal Patel , Nolan Brown , Shane Shahrestani , Julian Gendreau

The patient with ischemic stroke can benefit most from the earliest possible definitive diagnosis. While the high quality medical resources are quite scarce across the globe, an automated diagnostic tool is expected in analyzing the…

Computer Vision and Pattern Recognition · Computer Science 2018-03-16 Zhiyang Liu , Chen Cao , Shuxue Ding , Tong Han , Hong Wu , Sheng Liu

The automated detection of cortical lesions (CLs) in patients with multiple sclerosis (MS) is a challenging task that, despite its clinical relevance, has received very little attention. Accurate detection of the small and scarce lesions…

Image and Video Processing · Electrical Eng. & Systems 2020-08-18 Francesco La Rosa , Erin S Beck , Ahmed Abdulkadir , Jean-Philippe Thiran , Daniel S Reich , Pascal Sati , Meritxell Bach Cuadra

Localization of focal vascular lesions on brain MRI is an important component of research on the etiology of neurological disorders. However, manual annotation of lesions can be challenging, time-consuming and subject to observer bias.…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Kimberlin M. H. van Wijnen , Florian Dubost , Pinar Yilmaz , M. Arfan Ikram , Wiro J. Niessen , Hieab Adams , Meike W. Vernooij , Marleen de Bruijne

Diabetic retinopathy (DR) is a primary cause of blindness in working-age people worldwide. About 3 to 4 million people with diabetes become blind because of DR every year. Diagnosis of DR through color fundus images is a common approach to…

Computer Vision and Pattern Recognition · Computer Science 2020-03-27 Qilei Chen , Ping Liu , Jing Ni , Yu Cao , Benyuan Liu , Honggang Zhang

Patients with Frontotemporal Dementia (FTD) have impaired cognitive abilities, executive and behavioral traits, loss of language ability, and decreased memory capabilities. Based on the distinct patterns of cortical atrophy and symptoms,…

Artificial Intelligence · Computer Science 2021-04-13 Km Poonam , Rajlakshmi Guha , Partha P Chakrabarti

Fully convolutional deep neural networks have been asserted to be fast and precise frameworks with great potential in image segmentation. One of the major challenges in training such networks raises when data is unbalanced, which is common…

Computer Vision and Pattern Recognition · Computer Science 2018-12-17 Seyed Raein Hashemi , Seyed Sadegh Mohseni Salehi , Deniz Erdogmus , Sanjay P. Prabhu , Simon K. Warfield , Ali Gholipour

Age-related macular degeneration (AMD) is a degenerative disorder affecting the macula, a key area of the retina for visual acuity. Nowadays, it is the most frequent cause of blindness in developed countries. Although some promising…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 José Morano , Álvaro S. Hervella , José Rouco , Jorge Novo , José I. Fernández-Vigo , Marcos Ortega

The development of machine learning systems for the diagnosis of rare diseases is challenging mainly due the lack of data to study them. Despite this challenge, this paper proposes a system for the Computer Aided Diagnosis (CAD) of…

Computer Vision and Pattern Recognition · Computer Science 2019-02-01 Adrián Bazaga , Mònica Roldán , Carmen Badosa , Cecilia Jiménez-Mallebrera , Josep M. Porta

Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…

We propose an automatic diabetic retinopathy (DR) analysis algorithm based on two-stages deep convolutional neural networks (DCNN). Compared to existing DCNN-based DR detection methods, the proposed algorithm have the following advantages:…

Computer Vision and Pattern Recognition · Computer Science 2017-05-03 Yehui Yang , Tao Li , Wensi Li , Haishan Wu , Wei Fan , Wensheng Zhang

Diabetic retinopathy (DR) is a diabetes complication that affects eyes. DR is a primary cause of blindness in working-age people and it is estimated that 3 to 4 million people with diabetes are blinded by DR every year worldwide. Early…

Computer Vision and Pattern Recognition · Computer Science 2019-11-21 Qilei Chen , Xinzi Sun , Ning Zhang , Yu Cao , Benyuan Liu

Age-related macular degeneration (AMD) is the most common cause of blindness in developed countries, especially in people over 60 years of age. The workload of specialists and the healthcare system in this field has increased in recent…

Image and Video Processing · Electrical Eng. & Systems 2022-02-07 Saman Sotoudeh-Paima , Ata Jodeiri , Fedra Hajizadeh , Hamid Soltanian-Zadeh

Convolutional Neural Network models have successfully detected retinal illness from optical coherence tomography (OCT) and fundus images. These CNN models frequently rely on vast amounts of labeled data for training, difficult to obtain,…

Computer Vision and Pattern Recognition · Computer Science 2022-01-28 Sourya Dipta Das , Saikat Dutta , Nisarg A. Shah , Dwarikanath Mahapatra , Zongyuan Ge

Convolutional neural networks (CNNs) have gained significant popularity in orthopedic imaging in recent years due to their ability to solve fracture classification problems. A common criticism of CNNs is their opaque learning and reasoning…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Zhibin Liao , Kewen Liao , Haifeng Shen , Marouska F. van Boxel , Jasper Prijs , Ruurd L. Jaarsma , Job N. Doornberg , Anton van den Hengel , Johan W. Verjans

Alzheimer's Disease (AD) is one of the most concerned neurodegenerative diseases. In the last decade, studies on AD diagnosis attached great significance to artificial intelligence (AI)-based diagnostic algorithms. Among the diverse…

Computer Vision and Pattern Recognition · Computer Science 2019-08-20 Yechong Huang , Jiahang Xu , Yuncheng Zhou , Tong Tong , Xiahai Zhuang , the Alzheimer's Disease Neuroimaging Initiative

The presence of certain clinical dermoscopic features within a skin lesion may indicate melanoma, and automatically detecting these features may lead to more quantitative and reproducible diagnoses. We reformulate the task of classifying…

Computer Vision and Pattern Recognition · Computer Science 2019-03-28 Jeremy Kawahara , Ghassan Hamarneh
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