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Coordinated collaboration is essential to realize the added value of and infrastructure requirements for global image data sharing in the life sciences. In this White Paper, we take a first step at presenting some of the most common use…

Public data archives are the backbone of modern biological and biomedical research. While archives for biological molecules and structures are well-established, resources for imaging data do not yet cover the full range of spatial and…

Quantitative Methods · Quantitative Biology 2018-11-05 Jan Ellenberg , Jason R Swedlow , Mary Barlow , Charles E Cook , Ardan Patwardhan , Alvis Brazma , Ewan Birney

Modern research in the life sciences is unthinkable without computational methods for extracting, quantifying and visualizing information derived from biological microscopy imaging data. In the past decade, we observed a dramatic increase…

New technologies have enabled the investigation of biology and human health at an unprecedented scale and in multiple dimensions. These dimensions include a myriad of properties describing genome, epigenome, transcriptome, microbiome,…

Quantitative Methods · Quantitative Biology 2018-10-22 Marinka Zitnik , Francis Nguyen , Bo Wang , Jure Leskovec , Anna Goldenberg , Michael M. Hoffman

Nowadays, the amount of heterogeneous biomedical data is increasing more and more thanks to novel sensing techniques and high-throughput technologies. In reference to biomedical image analysis, the advances in image acquisition modalities…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Leonardo Rundo

The development of vision-language models (VLMs) is driven by large-scale and diverse multimodal datasets. However, progress toward generalist biomedical VLMs is limited by the lack of annotated, publicly accessible datasets across biology…

Brain Imaging Data Structure (BIDS) allows the user to organise brain imaging data into a clear and easy standard directory structure. BIDS is widely supported by the scientific community and is considered a powerful standard for…

Despite the excitement behind biomedical artificial intelligence (AI), access to high-quality, diverse, and large-scale data - the foundation for modern AI systems - is still a bottleneck to unlocking its full potential. To address this…

With the proliferation of inexpensive CMOS cameras, medical imaging experiences a noticeable influx of new technologies. While anatomical imaging is based on well-established principles of photography, physiological optical imaging is a…

Medical Physics · Physics 2023-02-02 Gennadi Saiko

The reproducibility of scientific research has become a point of critical concern. We argue that openness and transparency are critical for reproducibility, and we outline an ecosystem for open and transparent science that has emerged…

Computers and Society · Computer Science 2018-09-27 Russell A. Poldrack , Krzysztof J. Gorgolewski , Gael Varoquaux

This tutorial covers biomedical image reconstruction, from the foundational concepts of system modeling and direct reconstruction to modern sparsity and learning-based approaches. Imaging is a critical tool in biological research and…

Image and Video Processing · Electrical Eng. & Systems 2021-03-12 Michael T. McCann , Michael Unser

We collected 32 public datasets, of which 28 for medical imaging and 4 for natural images, to conduct study. The images of these datasets are captured by different cameras, thus vary from each other in modality, frame size and capacity. For…

Image and Video Processing · Electrical Eng. & Systems 2021-02-19 Yang Wen

With the acceleration of urbanization and living standards, microorganisms play increasingly important roles in industrial production, bio-technique, and food safety testing. Microorganism biovolume measurements are one of the essential…

Computer Vision and Pattern Recognition · Computer Science 2022-05-03 Jiawei Zhang , Chen Li , Md Mamunur Rahaman , Yudong Yao , Pingli Ma , Jinghua Zhang , Xin Zhao , Tao Jiang , Marcin Grzegorzek

In this paper, we present BIMS (Biomedical Information Management System). BIMS is a software architecture designed to provide a flexible computational framework to manage the information needs of a wide range of biomedical research…

Software Engineering · Computer Science 2013-03-26 Oscar Mora , Jesús Bisbal

The application of microscopy in biomedical research has come a long way since Antonie van Leeuwenhoek discovered unicellular organisms. Countless innovations have positioned light microscopy as a cornerstone of modern biology and a method…

Bio image analysis has recently become one keystone of biological research but biologists tend to get lost in a plethora of available software and the way to adjust available tools to their own image analysis problem. We present BIII,…

Light microscopy allows observing cellular features and objects with sub-micrometer resolution. As such, light microscopy has been playing a fundamental role in the life sciences for more than a hundred years. Fueled by the availability of…

Other Quantitative Biology · Quantitative Biology 2021-10-28 Johannes Hohlbein , Benedict Diederich , Barbora Marsikova , Emmanuel G. Reynaud , Seamus Holden , Wiebke Jahr , Robert Haase , Kirti Prakash

The Web community has introduced a set of standards and technologies for representing, querying, and manipulating a globally distributed data structure known as the Web of Data. The proponents of the Web of Data envision much of the world's…

Artificial Intelligence · Computer Science 2009-08-05 Marko A. Rodriguez

Omni-tomography is enabled by interior tomography that has been developed over the past five years. By omni-tomography, we envision that the next stage of biomedical imaging will be the grand fusion of many tomographic modalities into a…

Medical Physics · Physics 2012-12-24 Ge Wang , Yue Wang , Michael W. Vannier
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