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Multiple lines of evidence strongly suggest that infection hotspots, where a single individual infects many others, play a key role in the transmission dynamics of COVID-19. However, most of the existing epidemiological models fail to…

Motile organisms can form stable agglomerates such as cities or colonies. In the outbreak of a highly contagious disease, the control of large-scale epidemic spread depends on factors like the number and size of agglomerates, travel rate…

Populations and Evolution · Quantitative Biology 2023-04-03 Pablo de Castro , Felipe Urbina , Ariel Norambuena , Francisca Guzmán-Lastra

We consider a model for an epidemic in a population that occupies geographically distinct locations. The disease is spread within subpopulations by contacts between infective and susceptible individuals, and is spread between subpopulations…

Probability · Mathematics 2016-02-15 R. McVinish , P. K. Pollett , A. Shausan

In some systems, the behavior of the constituent units can create a `context' that modifies the direct interactions among them. This mechanism of indirect modification inspired us to develop a minimal model of context-dependent spreading.…

Physics and Society · Physics 2023-06-13 Giulio Burgio , Sergio Gómez , Alex Arenas

When the body gets infected by a pathogen the immune system develops pathogen-specific immunity. Induced immunity decays in time and years after recovery the host might become susceptible again. Exposure to the pathogen in the environment…

Dynamical Systems · Mathematics 2014-11-13 Maria Vittoria Barbarossa , Gergely Röst

It is increasingly important to understand the spatial dynamics of epidemics. While there are numerous mathematical models of epidemics, there is a scarcity of physical systems with sufficiently well-controlled parameters to allow…

Working in the multi-type Galton-Watson branching-process framework we analyse the spread of a pandemic via a general multi-type random contact graph. Our model consists of several communities, and takes, as input, parameters that outline…

Statistical Mechanics · Physics 2023-06-14 Dor Minzer , Yaron Oz , Muli Safra , Lior Wainstain

We study an infection-age structured epidemic model in which both the infectivity and the rate of loss of immunity depend on the time-since-infection. The model can be equivalently viewed as a nonlinear renewal equation for the incidence of…

Dynamical Systems · Mathematics 2025-11-13 Francesca Scarabel , Harry Coldwell , Tyler Cassidy

The Markovian approach, which assumes exponentially distributed interinfection times, is dominant in epidemic modeling. However, this assumption is unrealistic as an individual's infectiousness depends on its viral load and varies over…

Populations and Evolution · Quantitative Biology 2023-08-02 Qihui Yang , Joan Saldaña , Caterina Scoglio

An epidemic spreading in a network calls for a decision on the part of the network members: They should decide whether to protect themselves or not. Their decision depends on the trade-off between their perceived risk of being infected and…

Systems and Control · Computer Science 2015-03-17 George Theodorakopoulos , Jean-Yves Le Boudec , John S. Baras

Here we propose and implement a generalized mathematical model to find the time evolution of population in infectious diseases and apply the model to study the recent COVID-19 pandemic. Our model at the core is a non-local generalization of…

Populations and Evolution · Quantitative Biology 2020-05-01 Saumyak Mukherjee , Sayantan Mondal , Biman Bagchi

In this study we present a dynamical agent-based model to investigate the interplay between the socio-economy of and SEIRS-type epidemic spreading over a geographical area, divided to smaller area districts and further to smallest area…

Physics and Society · Physics 2022-07-20 Jan E. Snellman , Rafael A. Barrio , Kimmo K. Kaski , Maarit J. Käpylä

Pandemics, in addition to affecting the health of populations, can have huge impacts on their social and economic behavior. These factors, on the other hand, have the potential to feed back to and influence the disease spreading. It is…

Physics and Society · Physics 2022-09-28 Jan E. Snellman , Rafael A. Barrio , Kimmo K. Kaski , Maarit J. Korpi--Lagg

In this paper, we propose a modified susceptible-infected-recovered (SIR) model, in which each node is assigned with an identical capability of active contacts, $A$, at each time step. In contrast to the previous studies, we find that on…

Physics and Society · Physics 2007-05-23 Rui Yang , Bing-Hong Wang , Jie Ren , Wen-Jie Bai , Zhi-Wen Shi , Wen-Xu Wang , Tao Zhou

The outbreak of mutant strains and vaccination behaviors have been the focus of recent epidemiological research, but most existing epidemic models failed to simultaneously capture viral mutation and consider the complexity and behavioral…

Populations and Evolution · Quantitative Biology 2026-01-16 Wenjie Zhang , Yusheng Li , Qin Li , Guojun Huang , Minyu Feng

The challenges posed by epidemics and pandemics are immense, especially if the causes are novel. This article introduces a versatile open-source simulation framework designed to model intricate dynamics of infectious diseases across diverse…

Multiagent Systems · Computer Science 2023-11-17 Zenin Easa Panthakkalakath , Neeraj , Jimson Mathew

The decision of whether or not to vaccinate is a complex one. It involves the contribution both to a social good -- herd immunity -- and to one's own well being. It is informed by social influence, personal experience, education, and mass…

Populations and Evolution · Quantitative Biology 2022-02-15 Soya Miyoshi , Marko Jusup , Petter Holme

Due to its high lethality amongst the elderly, the safety of nursing homes has been of central importance during the COVID-19 pandemic. With test procedures becoming available at scale, such as antigen or RT-LAMP tests, and increasing…

Parameter inference and state estimation in stochastic and partially observed biological systems remain major problems in mathematical biology. In this work, we introduce a two-dimensional lattice graph model for the spread of infectious…

Quantitative Methods · Quantitative Biology 2026-05-29 Ihtisham Ul Haq , Serge Richard

We analyze an optimal control version of a simple SIRS epidemiology model. The policy maker can adopt policies to diminish the contact rate between infected and susceptible individuals, at a specific economic cost. The arrival of a vaccine…

Populations and Evolution · Quantitative Biology 2020-06-09 Evangelos Magirou