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In large scale multiple testing problems, a two-class empirical Bayes approach can be used to control the false discovery rate (Fdr) for the entire array of hypotheses under study. A sample splitting step is incorporated to modify that…

Computation · Statistics 2019-12-13 Paramita Chakraborty , Chong Ma , John Grego , James Lynch

The family-wise error rate (FWER) has been widely used in genome-wide association studies. With the increasing availability of functional genomics data, it is possible to increase the detection power by leveraging these genomic functional…

Methodology · Statistics 2020-12-25 Huijuan Zhou , Xianyang Zhang , Jun Chen

Well-known for its simplicity and effectiveness in classification, AdaBoost, however, suffers from overfitting when class-conditional distributions have significant overlap. Moreover, it is very sensitive to noise that appears in the…

Machine Learning · Statistics 2018-06-22 Zhi Xiao , Zhe Luo , Bo Zhong , Xin Dang

Adapting Foundation Models (FMs) for downstream tasks through Federated Learning (FL) emerges a promising strategy for protecting data privacy and valuable FMs. Existing methods fine-tune FM by allocating sub-FM to clients in FL, however,…

Machine Learning · Computer Science 2024-04-30 Zhaopeng Peng , Xiaoliang Fan , Yufan Chen , Zheng Wang , Shirui Pan , Chenglu Wen , Ruisheng Zhang , Cheng Wang

Algorithms that exploit factored Markov decision processes are far more sample-efficient than factor-agnostic methods, yet they assume a factored representation is known a priori -- a requirement that breaks down when the agent sees only…

Machine Learning · Computer Science 2025-10-06 Rafael Rodriguez-Sanchez , Cameron Allen , George Konidaris

In many domains such as healthcare or finance, data often come in different assays or measurement modalities, with features in each assay having a common theme. Simply concatenating these assays together and performing prediction can be…

Methodology · Statistics 2018-07-17 J. Kenneth Tay , Robert Tibshirani

We propose a method for multiple hypothesis testing with familywise error rate (FWER) control, called the i-FWER test. Most testing methods are predefined algorithms that do not allow modifications after observing the data. However, in…

Methodology · Statistics 2021-04-20 Boyan Duan , Aaditya Ramdas , Larry Wasserman

Diagnostic accuracy studies assess sensitivity and specificity of a new index test in relation to an established comparator or the reference standard. The development and selection of the index test is usually assumed to be conducted prior…

Methodology · Statistics 2022-08-30 Max Westphal , Antonia Zapf

Primarily motivated by the drug development process, several publications have now presented methodology for the design of multi-arm multi-stage experiments with normally distributed outcome variables of known variance. Here, we extend…

Methodology · Statistics 2017-12-04 Michael Grayling , James Wason , Adrian Mander

We consider large-scale studies in which thousands of significance tests are performed simultaneously. In some of these studies, the multiple testing procedure can be severely biased by latent confounding factors such as batch effects and…

Methodology · Statistics 2016-06-21 Jingshu Wang , Qingyuan Zhao , Trevor Hastie , Art B. Owen

With the emerging application of Federated Learning (FL) in decision-making scenarios, it is imperative to regulate model fairness to prevent disparities across sensitive groups (e.g., female, male). Current research predominantly focuses…

Machine Learning · Computer Science 2025-11-10 Li Zhang , Zhongxuan Han , Xiaohua Feng , Jiaming Zhang , Yuyuan Li , Chaochao Chen

In this paper, we propose a novel bootstrap algorithm that is more efficient than existing methods for approximating the distribution of the factor-augmented regression estimator for a rotated parameter vector. The regression is augmented…

Methodology · Statistics 2025-10-02 Peiyun Jiang , Takashi Yamagata

Estimating causal effects from observational data is challenging due to selection bias, which leads to imbalanced covariate distributions across treatment groups. Propensity score-based weighting methods are widely used to address this…

Machine Learning · Computer Science 2025-08-08 Ahmad Saeed Khan , Erik Schaffernicht , Johannes Andreas Stork

In many applications, a large number of features are collected with the goal to identify a few important ones. Sometimes, these features lie in a metric space with a known distance matrix, which partially reflects their co-importance…

Methodology · Statistics 2021-09-28 Xuechan Li , Anthony Sung , Jichun Xie

In many large scale multiple testing applications, the hypotheses often have a known graphical structure, such as gene ontology in gene expression data. Exploiting this graphical structure in multiple testing procedures can improve power as…

Methodology · Statistics 2018-12-04 Wenge Guo , Gavin Lynch , Joseph P. Romano

Multiple hypothesis testing has been widely applied to problems dealing with high-dimensional data, e.g., selecting significant variables and controlling the selection error rate. The most prevailing measure of error rate used in the…

Methodology · Statistics 2022-06-07 Xiaoya Sun , Yan Fu

Biased data can lead to unfair machine learning models, highlighting the importance of embedding fairness at the beginning of data analysis, particularly during dataset curation and labeling. In response, we propose Falcon, a scalable fair…

Machine Learning · Computer Science 2024-01-25 Ki Hyun Tae , Hantian Zhang , Jaeyoung Park , Kexin Rong , Steven Euijong Whang

In this paper, we introduce a variation of the group testing problem capturing the idea that a positive test requires a combination of multiple ``types'' of item. Specifically, we assume that there are multiple disjoint \emph{semi-defective…

Information Theory · Computer Science 2024-05-10 Thach V. Bui , Jonathan Scarlett

The Dunnett procedure compares several treatment or dose groups with a control group, while controlling the familywise error rate. When deviations from the normal distribution and heterogeneous variances occur, the nominal $\alpha$ level…

Applications · Statistics 2019-05-07 Ludwig A. Hothorn , Felix M. Kluxen

Accelerated failure time (AFT) models are used widely in medical research, though to a much lesser extent than proportional hazards models. In an AFT model, the effect of covariates act to accelerate or decelerate the time to event of…

Methodology · Statistics 2020-06-15 Michael J. Crowther , Patrick Royston , Mark Clements