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Despite the progress in medical data collection the actual burden of SARS-CoV-2 remains unknown due to under-ascertainment of cases. This was apparent in the acute phase of the pandemic and the use of reported deaths has been pointed out as…

Applications · Statistics 2023-07-13 Anastasia Chatzilena , Nikolaos Demiris , Konstantinos Kalogeropoulos

We introduce the concept of epidemic-fitted wavelets which comprise, in particular, as special cases the number $I(t)$ of infectious individuals at time $t$ in classical SIR models and their derivatives. We present a novel method for…

In a previous article [1] we have described the temporal evolution of the Sars- Cov-2 in Italy in the time window February 24-April 1. As we can see in [1] a generalized logistic equation captures both the peaks of the total infected and…

Populations and Evolution · Quantitative Biology 2020-08-26 Gabriele Martelloni , Gianluca Martelloni

This work provides an overview on deterministic and stochastic models that have previously been proposed by us to study the transmission dynamics of the Coronavirus Disease 2019 (COVID-19) in Europe and USA. Briefly, we describe realistic…

Populations and Evolution · Quantitative Biology 2022-07-11 Giorgio Sonnino , Philippe Peeters , Pasquale Nardone

We propose a mathematical model with five compartments for the SARS-CoV-2 transmission: susceptible $S$, undetected infected asymptomatic $A$, undetected infected symptomatic $I$, confirmed positive and isolated $L$, and recovered $ R$, for…

Optimization and Control · Mathematics 2020-09-29 Gabriela Marinoschi

A pipeline to evaluate the evolution of viral dynamics based on a new model-driven approach has been developed in the present study. The proposed methods exploit real data and the multiscale structure of the infection dynamics to provide…

Populations and Evolution · Quantitative Biology 2025-11-25 Andrea Bondesan , Antonio Piralla , Elena Ballante , Antonino Maria Guglielmo Pitrolo , Silvia Figini , Fausto Baldanti , Mattia Zanella

In this work, we derive a system of Boltzmann-type equations to describe the spread of SARS-CoV-2 virus at the microscopic scale, that is by modeling the human-to-human mechanisms of transmission. To this end, we consider two populations,…

Populations and Evolution · Quantitative Biology 2024-02-09 Marzia Bisi , Silvia Lorenzani

This paper shows that the generalized logistic distribution model is derived from the well-known compartment model, consisting of susceptible, infected and recovered compartments, abbreviated as the SIR model, under certain conditions. In…

Applications · Statistics 2020-10-06 Hideo Hirose

This paper presents a critical analysis of the literature and perspective research ideas for modeling the epidemics caused by the SARS-CoV-2 virus. It goes beyond deterministic population dynamics to consider several key complexity features…

Populations and Evolution · Quantitative Biology 2025-01-24 Giulia Bertaglia , Andrea Bondesan , Diletta Burini , Raluca Eftimie , Lorenzo Pareschi , Giuseppe Toscani

The generalized logistic equation is used to interpret the COVID-19 epidemic data in several countries: Austria, Switzerland, the Netherlands, Italy, Turkey and South Korea. The model coefficients are calculated: the growth rate and the…

Populations and Evolution · Quantitative Biology 2021-02-03 Efim Pelinovsky , Andrey Kurkin , Oxana Kurkina , Maria Kokoulina , Anastasia Epifanova

A novel yet simple extension of the symmetric logistic distribution is proposed by introducing a skewness parameter. It is shown how the three parameters of the ensuing skew logistic distribution may be estimated using maximum likelihood.…

Physics and Society · Physics 2022-05-06 Mark Levene

The current SARS-CoV-2 pandemic is a harsh reminder of the fact that, whether in a single human host or a wave of infection across continents, viral dynamics is often a story about the numbers. In this snapshot, our aim is to provide a…

Other Quantitative Biology · Quantitative Biology 2020-04-01 Yinon M. Bar-On , Avi I. Flamholz , Rob Phillips , Ron Milo

During an infectious disease outbreak, providing accurate answers to policy questions about transmission requires a detailed model of the natural history of infectiousness. Unfortunately, direct measures of infectiousness are generally…

The determination of the infection fatality rate (IFR) for the novel SARS-CoV-2 coronavirus is a key aim for many of the field studies that are currently being undertaken in response to the pandemic. The IFR together with the basic…

How may exposure risks to SARS-CoV-2 be assessed quantitatively? The material metabolism approach of Industrial Ecology can be applied to the mass flows of these virions by their numbers, as a key step in the analysis of the current…

Quantitative Methods · Quantitative Biology 2020-10-30 Gjalt Huppes , Ruben Huele

There are many sources of data giving information about the number of SARS-CoV-2 infections in the population, but all have major drawbacks, including biases and delayed reporting. For example, the number of confirmed cases largely…

Applications · Statistics 2022-06-08 Nicholas J. Irons , Adrian E. Raftery

In this paper, we present a method to forecast the spread of SARS-CoV-2 across regions with a focus on the role of mobility. Mobility has previously been shown to play a significant role in the spread of the virus, particularly between…

Optimization and Control · Mathematics 2023-02-28 Martijn H. H. Schoot Uiterkamp , Martijn Gösgens , Hans Heesterbeek , Remco van der Hofstad , Nelly Litvak

The viral load of patients infected with SARS-CoV-2 varies on logarithmic scales and possibly with age. Controversial claims have been made in the literature regarding whether the viral load distribution actually depends on the age of the…

In this work we propose the design principles of a stochastic graph-based model for the simulation of SARS-CoV-2 transmission. The proposed approach incorporates three sub-models, namely, the spatial model, the mobility model, and the…

Physics and Society · Physics 2021-11-11 Christos Chondros , Stavros D. Nikolopoulos , Iosif Polenakis

We introduce a new probabilistic model to estimate the real spread of the novel SARS-CoV-2 virus along regions or countries. Our model simulates the behavior of each individual in a population according to a probabilistic model through an…

Populations and Evolution · Quantitative Biology 2020-05-05 Marcos Matabuena , Carlos Meijide-García , Pablo Rodríguez-Mier , Víctor Leborán
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