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We propose a constrained maximum partial likelihood estimator for dimension reduction in integrative (e.g., pan-cancer) survival analysis with high-dimensional covariates. We assume that for each population in the study, the hazard function…

Methodology · Statistics 2023-04-27 Aaron J. Molstad , Rohit K. Patra

Estimation of Markov Random Field and covariance models from high-dimensional data represents a canonical problem that has received a lot of attention in the literature. A key assumption, widely employed, is that of {\em sparsity} of the…

Optimization and Control · Mathematics 2018-05-16 Davoud Ataee Tarzanagh , George Michailidis

Regression models with both high-dimensional responses and covariates have attracted growing attention. Standard multivariate regression models become inadequate when the response variables depend not only on observed covariates but also on…

Methodology · Statistics 2026-05-01 Jing Ouyang , Chengyu Cui , Yunxiao Chen , Kean Ming Tan , Gongjun Xu

This paper investigates a change-point estimation problem in the context of high-dimensional Markov Random Field models. Change-points represent a key feature in many dynamically evolving network structures. The change-point estimate is…

Methodology · Statistics 2018-02-13 Sandipan Roy , Yves Atchade , George Michailidis

We propose a new inferential framework for constructing confidence regions and testing hypotheses in statistical models specified by a system of high dimensional estimating equations. We construct an influence function by projecting the…

Statistics Theory · Mathematics 2016-06-24 Matey Neykov , Yang Ning , Jun S. Liu , Han Liu

This paper presents a novel method to make statistical inferences for both the model support and regression coefficients in a high-dimensional logistic regression model. Our method is based on the repro samples framework, in which we…

Methodology · Statistics 2024-03-18 Xiaotian Hou , Linjun Zhang , Peng Wang , Min-ge Xie

We propose a new computationally efficient sampling scheme for Bayesian inference involving high dimensional probability distributions. Our method maps the original parameter space into a low-dimensional latent space, explores the latent…

Computation · Statistics 2019-10-15 Babak Shahbaba , Luis Martinez Lomeli , Tian Chen , Shiwei Lan

Most data sets comprise of measurements on continuous and categorical variables. In regression and classification Statistics literature, modeling high-dimensional mixed predictors has received limited attention. In this paper we study the…

Statistics Theory · Mathematics 2021-10-26 Efstathia Bura , Liliana Forzani , Rodrigo García Arancibia , Pamela Llop , Diego Tomassi

Inference of the marginal probability distribution is defined as the calculation of the probability of a subset of the variables and is relevant for handling missing data and hidden variables. While inference of the marginal probability…

Machine Learning · Statistics 2022-07-22 Fritz M. Bayer , Giusi Moffa , Niko Beerenwinkel , Jack Kuipers

Identifying co-varying causal elements in very high dimensional feature space with internal structures, e.g., a space with as many as millions of linearly ordered features, as one typically encounters in problems such as whole genome…

Methodology · Statistics 2012-06-18 Seyoung Kim , Eric P. Xing

The Markov property is widely imposed in analysis of time series data. Correspondingly, testing the Markov property, and relatedly, inferring the order of a Markov model, are of paramount importance. In this article, we propose a…

Machine Learning · Statistics 2023-05-31 Yunzhe Zhou , Chengchun Shi , Lexin Li , Qiwei Yao

Multivariate regression model is a natural generalization of the classical univari- ate regression model for fitting multiple responses. In this paper, we propose a high- dimensional multivariate conditional regression model for…

Machine Learning · Statistics 2016-11-26 Junhui Wang

This article is motivated by the objective of providing a new analytically tractable and fully frequentist framework to characterize and implement regression trees while also allowing a multivariate (potentially high dimensional) response.…

Methodology · Statistics 2021-05-24 Abhishek Kaul

We propose a novel and computationally efficient approach for nonparametric conditional density estimation in high-dimensional settings that achieves dimension reduction without imposing restrictive distributional or functional form…

Econometrics · Economics 2025-10-14 Jianhua Mei , Fu Ouyang , Thomas T. Yang

Principal Component Analysis is a key technique for reducing the complexity of high-dimensional data while preserving its fundamental data structure, ensuring models remain stable and interpretable. This is achieved by transforming the…

Methodology · Statistics 2025-03-25 Nuwan Weeraratne , Lyn Hunt , Jason Kurz

Motivated by the problem of inferring the graph structure of functional connectivity networks from multi-level functional magnetic resonance imaging data, we develop a valid inference framework for high-dimensional graphical models that…

Methodology · Statistics 2024-03-18 Kun Yue , Eardi Lila , Ali Shojaie

Deep neural networks are frequently used by autonomous systems for their ability to learn complex, non-linear data patterns and make accurate predictions in dynamic environments. However, their use as black boxes introduces risks as the…

Machine Learning · Computer Science 2021-10-08 Dimitrios Boursinos , Xenofon Koutsoukos

Developing feature selection algorithms that move beyond a pure correlational to a more causal analysis of observational data is an important problem in the sciences. Several algorithms attempt to do so by discovering the Markov blanket of…

Machine Learning · Statistics 2014-05-06 Eric V. Strobl , Shyam Visweswaran

High-dimensional data sets are often available in genome-enabled predictions. Such data sets include nonlinear relationships with complex dependence structures. For such situations, vine copula based (quantile) regression is an important…

Methodology · Statistics 2024-01-24 Özge Sahin , Claudia Czado

We consider the problem of estimating the graph associated with a binary Ising Markov random field. We describe a method based on $\ell_1$-regularized logistic regression, in which the neighborhood of any given node is estimated by…

Statistics Theory · Mathematics 2010-10-05 Pradeep Ravikumar , Martin J. Wainwright , John D. Lafferty