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Generative models have emerged as powerful tools in medical imaging, enabling tasks such as segmentation, anomaly detection, and high-quality synthetic data generation. These models typically rely on learning meaningful latent…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Jordi Malé , Juan Fortea , Mateus Rozalem-Aranha , Neus Martínez-Abadías , Xavier Sevillano

Deep generative models have been accelerating the inverse design process in material and drug design. Unlike their counterpart property predictors in typical molecular design frameworks, generative molecular design models have seen fewer…

Machine Learning · Computer Science 2024-11-06 A N M Nafiz Abeer , Sanket Jantre , Nathan M Urban , Byung-Jun Yoon

A variational autoencoder (VAE) derived from Tsallis statistics called q-VAE is proposed. In the proposed method, a standard VAE is employed to statistically extract latent space hidden in sampled data, and this latent space helps make…

Machine Learning · Computer Science 2021-08-27 Taisuke Kobayashi

Extracting compact, physically interpretable representations from high-dimensional scientific data is a persistent challenge due to the complex, nonlinear structures inherent in physical systems. We propose a Gaussian Mixture Variational…

Machine Learning · Computer Science 2025-12-01 Tiffany Fan , Murray Cutforth , Marta D'Elia , Alexandre Cortiella , Alireza Doostan , Eric Darve

Variational autoencoders are powerful algorithms for identifying dominant latent structure in a single dataset. In many applications, however, we are interested in modeling latent structure and variation that are enriched in a target…

Machine Learning · Computer Science 2019-02-14 Abubakar Abid , James Zou

This study explores the use of the Dirichlet Variational Autoencoder (DirVAE) for learning disentangled latent representations of chest X-ray (CXR) images. Our working hypothesis is that distributional sparsity, as facilitated by the…

Computer Vision and Pattern Recognition · Computer Science 2023-02-07 Rachael Harkness , Alejandro F Frangi , Kieran Zucker , Nishant Ravikumar

Elucidating the functional mechanisms of the primary visual cortex (V1) remains a fundamental challenge in systems neuroscience. Current computational models face two critical limitations, namely the challenge of cross-modal integration…

Neurons and Cognition · Quantitative Biology 2024-12-20 Yu Zhu , Bo Lei , Chunfeng Song , Wanli Ouyang , Shan Yu , Tiejun Huang

Longitudinal datasets measured repeatedly over time from individual subjects, arise in many biomedical, psychological, social, and other studies. A common approach to analyse high-dimensional data that contains missing values is to learn a…

Machine Learning · Statistics 2021-04-21 Siddharth Ramchandran , Gleb Tikhonov , Kalle Kujanpää , Miika Koskinen , Harri Lähdesmäki

One noted issue of vector-quantized variational autoencoder (VQ-VAE) is that the learned discrete representation uses only a fraction of the full capacity of the codebook, also known as codebook collapse. We hypothesize that the training…

Spatio-temporal compression of videos, utilizing networks such as Variational Autoencoders (VAE), plays a crucial role in OpenAI's SORA and numerous other video generative models. For instance, many LLM-like video models learn the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-24 Sijie Zhao , Yong Zhang , Xiaodong Cun , Shaoshu Yang , Muyao Niu , Xiaoyu Li , Wenbo Hu , Ying Shan

Variational Auto-Encoders (VAEs) are capable of learning latent representations for high dimensional data. However, due to the i.i.d. assumption, VAEs only optimize the singleton variational distributions and fail to account for the…

Machine Learning · Computer Science 2020-04-20 Da Tang , Dawen Liang , Tony Jebara , Nicholas Ruozzi

The variational autoencoder (VAE) is a simple and efficient generative artificial intelligence method for modeling complex probability distributions of various types of data, such as images and texts. However, it suffers some main…

Machine Learning · Computer Science 2025-02-14 Xi Chen , Shaofan Li

The ability to accurately model random fields plays a critical role in science and engineering for problems involving uncertain, spatially-varying quantities such as heterogeneous material properties and turbulent flows. Deep generative…

An important task in quantum generative machine learning is to model the probability distribution of measurements of many-body quantum systems. Classical generative models, such as generative adversarial networks (GANs) and variational…

Quantum Physics · Physics 2023-05-19 Anantha Rao , Dhiraj Madan , Anupama Ray , Dhinakaran Vinayagamurthy , M. S. Santhanam

Variational autoencoders are prominent generative models for modeling discrete data. However, with flexible decoders, they tend to ignore the latent codes. In this paper, we study a VAE model with a deterministic decoder (DD-VAE) for…

Machine Learning · Computer Science 2020-03-05 Daniil Polykovskiy , Dmitry Vetrov

Estimating causal effects from observational data is challenging, especially in the presence of latent confounders. Much work has been done on addressing this challenge, but most of the existing research ignores the bias introduced by the…

Machine Learning · Computer Science 2024-08-15 Yang Xie , Ziqi Xu , Debo Cheng , Jiuyong Li , Lin Liu , Yinghao Zhang , Zaiwen Feng

The increasing efficiency and compactness of deep learning architectures, together with hardware improvements, have enabled the complex and high-dimensional modelling of medical volumetric data at higher resolutions. Recently,…

Image and Video Processing · Electrical Eng. & Systems 2020-02-14 Petru-Daniel Tudosiu , Thomas Varsavsky , Richard Shaw , Mark Graham , Parashkev Nachev , Sebastien Ourselin , Carole H. Sudre , M. Jorge Cardoso

Gastrointestinal (GI) imaging via Wireless Capsule Endoscopy (WCE) generates a large number of images requiring manual screening. Deep learning-based Clinical Decision Support (CDS) systems can assist screening, yet their performance relies…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Dimitrios E. Diamantis , Dimitris K. Iakovidis

Variational autoencoders (VAEs) are fundamental for generative modeling and image reconstruction, yet their performance often struggles to maintain high fidelity in reconstructions. This study introduces a hybrid model, quantum variational…

Computer Vision and Pattern Recognition · Computer Science 2025-03-10 Farina Riaz , Fakhar Zaman , Hajime Suzuki , Sharif Abuadbba , David Nguyen

We propose a variational autoencoder (VAE) approach for parameter estimation in nonlinear mixed-effects models based on ordinary differential equations (NLME-ODEs) using longitudinal data from multiple subjects. In moderate dimensions,…

Methodology · Statistics 2026-02-11 Zhe Li , Mélanie Prague , Rodolphe Thiébaut , Quentin Clairon
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