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The outbreak of COVID-19 has highlighted the intricate interplay between public health and economic stability on a global scale. This study proposes a novel reinforcement learning framework designed to optimize health and economic outcomes…

Machine Learning · Computer Science 2024-05-01 Maeghal Jain , Ziya Uddin , Wubshet Ibrahim

Background: Over the past few decades, numerous forecasting methods have been proposed in the field of epidemic forecasting. Such methods can be classified into different categories such as deterministic vs. probabilistic, comparative…

The management of hyperglycemia in hospitalized patients has a significant impact on both morbidity and mortality. Therefore, it is important to predict the need for diabetic patients to be hospitalized. However, using standard machine…

Artificial Intelligence · Computer Science 2022-08-02 Shaina Raza

Drug overdose deaths, including those due to prescription opioids, represent a critical public health issue in the United States and worldwide. Artificial intelligence (AI) approaches have been developed and deployed to help prescribers…

Human-Computer Interaction · Computer Science 2025-02-18 Venkatesh Sivaraman , Yejun Kwak , Courtney Kuza , Qingnan Yang , Kayleigh Adamson , Katie Suda , Lu Tang , Walid Gellad , Adam Perer

In this paper, we study the dynamics of epidemic processes taking place in temporal and adaptive networks. Building on the activity-driven network model, we propose an adaptive model of epidemic processes, where the network topology…

Social and Information Networks · Computer Science 2018-02-27 Masaki Ogura , Victor M. Preciado , Naoki Masuda

Decisions on public health interventions to control infectious disease are often informed by computational models. Interpreting the predicted outcomes of a public health decision requires not only high-quality modelling, but also an ethical…

We present nonparametric algorithms for estimating optimal individualized treatment rules. The proposed algorithms are based on the XGBoost algorithm, which is known as one of the most powerful algorithms in the machine learning literature.…

Machine Learning · Statistics 2020-02-04 Duzhe Wang , Haoda Fu , Po-Ling Loh

In the first stage of a two-stage study, the researcher uses a statistical model to impute the unobserved exposures. In the second stage, imputed exposures serve as covariates in epidemiological models. Imputation error in the first stage…

Applications · Statistics 2021-07-19 Ron Sarafian , Itai Kloog , Jonathan D. Rosenblatt

The design of an efficient curing policy, able to stem an epidemic process at an affordable cost, has to account for the structure of the population contact network supporting the contagious process. Thus, we tackle the problem of…

Optimization and Control · Mathematics 2017-12-04 Stefania Ottaviano , Francesco De Pellegrini , Stefano Bonaccorsi , Piet Van Mieghem

We analyze the optimal control of disease prevention and treatment in a basic SIS model. We develop a simple macroeconomic setup in which the social planner determines how to optimally intervene, through income taxation, in order to…

Theoretical Economics · Economics 2019-10-09 Davide La Torre , Tufail Malik , Simone Marsiglio

Stochastic infectious disease models capture uncertainty in public health outcomes and have become increasingly popular in epidemiological practice. However, calibrating these models to observed data is challenging with existing methods for…

Methodology · Statistics 2024-12-18 Prayag Chatha , Fan Bu , Jeffrey Regier , Evan Snitkin , Jon Zelner

In optimal control problem, policy iteration (PI) is a powerful reinforcement learning (RL) tool used for designing optimal controller for the linear systems. However, the need for an initial stabilizing control policy significantly limits…

Optimization and Control · Mathematics 2024-11-13 Zhen Pang , Shengda Tang , Jun Cheng , Shuping He

Imitation learning has enabled robots to perform complex, long-horizon tasks in challenging dexterous manipulation settings. As new methods are developed, they must be rigorously evaluated and compared against corresponding baselines…

Policy optimization is an effective reinforcement learning approach to solve continuous control tasks. Recent achievements have shown that alternating online and offline optimization is a successful choice for efficient trajectory reuse.…

Machine Learning · Computer Science 2018-11-01 Alberto Maria Metelli , Matteo Papini , Francesco Faccio , Marcello Restelli

Sepsis is a leading cause of death in the ICU. It is a disease requiring complex interventions in a short period of time, but its optimal treatment strategy remains uncertain. Evidence suggests that the practices of currently used treatment…

Machine Learning · Computer Science 2022-07-15 Zeyu Wang , Huiying Zhao , Peng Ren , Yuxi Zhou , Ming Sheng

In this paper, we propose a model predictive control (MPC) method for real-time intervention of spreading processes, such as epidemics and wildfire, over large-scale networks. The goal is to allocate budgeted resources each time step to…

Optimization and Control · Mathematics 2022-10-31 Ruigang Wang , Armaghan Zafar , Ian R. Manchester

During a pandemic, there are conflicting demands arising from public health and economic cost. Lockdowns are a common way of containing infections, but they adversely affect the economy. We study the question of how to minimise the economic…

Populations and Evolution · Quantitative Biology 2021-04-28 Joseph Samuel , Supurna Sinha

Globally, the outbreaks of infectious diseases have exerted an extremely profound and severe influence on health security and the economy. During the critical phases of epidemics, devising effective intervention measures poses a significant…

Machine Learning · Computer Science 2025-05-08 Baida Zhang , Yakai Chen , Huichun Li , Zhenghu Zu

Many public health threats exist, motivating the need to find optimal intervention strategies. Given the stochastic nature of the threats (e.g., the spread of pandemic influenza, the occurrence of drug overdoses, and the prevalence of…

Optimization and Control · Mathematics 2022-06-29 Zewei Li , James C. Spall

Without vaccines and treatments, societies must rely on non-pharmaceutical intervention strategies to control the spread of emerging diseases such as COVID-19. Though complete lockdown is epidemiologically effective, because it eliminates…

Populations and Evolution · Quantitative Biology 2021-01-08 Jason Hindes , Simone Bianco , Ira B. Schwartz