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Reliable cell segmentation and classification from biomedical images is a crucial step for both scientific research and clinical practice. A major challenge for more robust segmentation and classification methods is the large variations in…

Cell Behavior · Quantitative Biology 2017-10-31 Mo Zhang , Xiang Li , Mengjia Xu , Quanzheng Li

The quantitative analysis of cellular membranes helps understanding developmental processes at the cellular level. Particularly 3D microscopic image data offers valuable insights into cell dynamics, but error-free automatic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2018-10-17 Dennis Eschweiler , Thiago V. Spina , Rohan C. Choudhury , Elliot Meyerowitz , Alexandre Cunha , Johannes Stegmaier

For the diagnosis of Chinese medicine, tongue segmentation has reached a fairly mature point, but it has little application in the eye diagnosis of Chinese medicine.First, this time we propose Res-UNet based on the architecture of the U2Net…

Image and Video Processing · Electrical Eng. & Systems 2022-12-07 Peng Hong

Cell segmentation is a fundamental task for computational biology analysis. Identifying the cell instances is often the first step in various downstream biomedical studies. However, many cell segmentation algorithms, including the recently…

Computer Vision and Pattern Recognition · Computer Science 2022-12-08 Gihun Lee , Sangmook Kim , Joonkee Kim , Se-Young Yun

Melanoma is the deadliest form of skin cancer. Computer systems can assist in melanoma detection, but are not widespread in clinical practice. In 2016, an open challenge in classification of dermoscopic images of skin lesions was announced.…

Machine Learning · Statistics 2018-02-06 Kajsa Møllersen , Maciel Zortea , Thomas R. Schopf , Herbert Kirchesch , Fred Godtliebsen

This work explores a hybrid approach to segmentation as an alternative to a purely data-driven approach. We introduce an end-to-end U-Net based network called DU-Net, which uses additional frequency preserving features, namely the…

Image and Video Processing · Electrical Eng. & Systems 2020-04-16 Alakh Desai , Ruchi Chauhan , Jayanthi Sivaswamy

Obtaining high-resolution (HR) segmentations from coarse annotations is a pervasive challenge in computer vision. Applications include inferring pixel-level segmentations from token-level labels in vision transformers, upsampling coarse…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Xiaoling Hu , Peirong Liu , Dina Zemlyanker , Jonathan Williams Ramirez , Oula Puonti , Juan Eugenio Iglesias

Medical image segmentation is vital to the area of medical imaging because it enables professionals to more accurately examine and understand the information offered by different imaging modalities. The technique of splitting a medical…

Image and Video Processing · Electrical Eng. & Systems 2024-09-01 Aitik Gupta , Joydip Dhar

In the domain of computer vision, semantic segmentation emerges as a fundamental application within machine learning, wherein individual pixels of an image are classified into distinct semantic categories. This task transcends traditional…

Artificial Intelligence · Computer Science 2024-04-09 Qitian Ma , Shyam Nanda Rai , Carlo Masone , Tatiana Tommasi

Deep learning has revolutionized medical and biological imaging, particularly in segmentation tasks. However, segmenting biological cells remains challenging due to the high variability and complexity of cell shapes. Addressing this…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Tianhao Zhang , Heather J. McCourty , Berardo M. Sanchez-Tafolla , Anton Nikolaev , Lyudmila S. Mihaylova

Blood cell classification and counting are vital for the diagnosis of various blood-related diseases, such as anemia, leukemia, and thrombocytopenia. The manual process of blood cell classification and counting is time-consuming, prone to…

Image and Video Processing · Electrical Eng. & Systems 2024-05-27 Sohag Kumar Mondal , Md. Simul Hasan Talukder , Mohammad Aljaidi , Rejwan Bin Sulaiman , Md Mohiuddin Sarker Tushar , Amjad A Alsuwaylimi

Single-cell omics enable the profiles of cells, which contain large numbers of biological features, to be quantified. Cluster analysis, a dimensionality reduction process, is used to reduce the dimensions of the data to make it…

Genomics · Quantitative Biology 2024-06-06 Okezue Bell , Arthur Lee , Elizabeth Engle

Diseases such as diabetic retinopathy and age-related macular degeneration pose a significant risk to vision, highlighting the importance of precise segmentation of retinal vessels for the tracking and diagnosis of progression. However,…

Image and Video Processing · Electrical Eng. & Systems 2023-09-08 Tariq M. Khan , Muhammad Arsalan , Shahzaib Iqbal , Imran Razzak , Erik Meijering

Background: Brain tumor segmentation has a significant impact on the diagnosis and treatment of brain tumors. Accurate brain tumor segmentation remains challenging due to their irregular shapes, vague boundaries, and high variability.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-07 Zhanyuan Jia , Ni Yao , Danyang Sun , Chuang Han , Yanting Li , Jiaofen Nan , Fubao Zhu , Chen Zhao , Weihua Zhou

To assist researchers to identify Environmental Microorganisms (EMs) effectively, a Multiscale CNN-CRF (MSCC) framework for the EM image segmentation is proposed in this paper. There are two parts in this framework: The first is a novel…

Computer Vision and Pattern Recognition · Computer Science 2021-02-25 Jinghua Zhang , Chen Li , Frank Kulwa , Xin Zhao , Changhao Sun , Zihan Li , Tao Jiang , Hong Li , Shouliang Qi

Diagnoses from histopathology images rely on information from both high and low resolutions of Whole Slide Images. Ultra-Resolution Cascaded Diffusion Models (URCDMs) allow for the synthesis of high-resolution images that are realistic at…

Image and Video Processing · Electrical Eng. & Systems 2023-12-05 Sarah Cechnicka , Hadrien Reynaud , James Ball , Naomi Simmonds , Catherine Horsfield , Andrew Smith , Candice Roufosse , Bernhard Kainz

Electroluminescence (EL) imaging is widely used to detect defects in photovoltaic (PV) modules, and machine learning methods have been applied to enable large-scale analysis of EL images. However, existing methods cannot assign multiple…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Ojas Sanghi , Norman Jost , Benjamin G. Pierce , Emma Cooper , Isaiah H. Deane , Jennifer L. Braid

Brain tumor segmentation presents a formidable challenge in the field of Medical Image Segmentation. While deep-learning models have been useful, human expert segmentation remains the most accurate method. The recently released Segment…

Image and Video Processing · Electrical Eng. & Systems 2023-10-11 Mohammad Peivandi , Jason Zhang , Michael Lu , Dongxiao Zhu , Zhifeng Kou

High-throughput screening using automated microscopes is a key driver in biopharma drug discovery, enabling the parallel evaluation of thousands of drug candidates for diseases such as cancer. Traditional image analysis and deep learning…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Jacob Hanimann , Daniel Siegismund , Mario Wieser , Stephan Steigele

Segmentation of ultra-high resolution (UHR) images is a critical task with numerous applications, yet it poses significant challenges due to high spatial resolution and rich fine details. Recent approaches adopt a dual-branch architecture,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-24 Haopeng Sun , Yingwei Zhang , Lumin Xu , Sheng Jin , Yiqiang Chen