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Images from Positron Emission Tomography (PET) deliver functional data such as perfusion and metabolism. On the other hand, images from Magnetic Resonance Imaging (MRI) provide information describing anatomical structures. Fusing the…
Non-rigid registration is a necessary but challenging task in medical imaging studies. Recently, unsupervised registration models have shown good performance, but they often require a large-scale training dataset and long training times.…
Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) automatic 3-D registration is implemented and validated for small animal image volumes so that the high-resolution anatomical MRI information can be fused with the low…
Deformable templates, or atlases, are images that represent a prototypical anatomy for a population, and are often enhanced with probabilistic anatomical label maps. They are commonly used in medical image analysis for population studies…
Large high-quality medical image datasets are difficult to acquire but necessary for many deep learning applications. For positron emission tomography (PET), reconstructed image quality is limited by inherent Poisson noise. We propose a…
Template estimation plays a crucial role in computational anatomy since it provides reference frames for performing statistical analysis of the underlying anatomical population variability. While building models for template estimation,…
We present a meta-learning framework for interactive medical image registration. Our proposed framework comprises three components: a learning-based medical image registration algorithm, a form of user interaction that refines registration…
Many applications in image-guided surgery and therapy require fast and reliable non-linear, multi-modal image registration. Recently proposed unsupervised deep learning-based registration methods have demonstrated superior performance…
Non-rigid inter-modality registration can facilitate accurate information fusion from different modalities, but it is challenging due to the very different image appearances across modalities. In this paper, we propose to train a non-rigid…
Transcranial ultrasound must overcome the significant challenge of the human skull, limiting both imaging and therapeutic applications. While high-fidelity numerical simulations can compensate for skull-induced distortions, they require…
Deformable registration of magnetic resonance images between patients with brain tumors and healthy subjects has been an important tool to specify tumor geometry through location alignment and facilitate pathological analysis. Since tumor…
Medical image registration is critical for aligning anatomical structures across imaging modalities such as computed tomography (CT), magnetic resonance imaging (MRI), and ultrasound. Among existing techniques, non-rigid registration (NRR)…
Even though simultaneous optimization of similarity metrics is a standard procedure in the field of semantic segmentation, surprisingly, this is much less established for image registration. To help closing this gap in the literature, we…
Image registration is fundamental in medical imaging, enabling precise alignment of anatomical structures for diagnosis, treatment planning, image-guided interventions, and longitudinal monitoring. This work introduces IMPACT (Image Metric…
Objective: Deep learning-based deformable image registration has achieved strong accuracy, but remains sensitive to variations in input image characteristics such as artifacts, field-of-view mismatch, or modality difference. We aim to…
We propose a variational regularisation approach for the problem of template-based image reconstruction from indirect, noisy measurements as given, for instance, in X-ray computed tomography. An image is reconstructed from such measurements…
Analysis of longitudinal changes in imaging studies often involves both segmentation of structures of interest and registration of multiple timeframes. The accuracy of such analysis could benefit from a tailored framework that jointly…
Since the mapping relationship between definitized intra-interventional X-ray and undefined pre-interventional Computed Tomography(CT) is uncertain, auxiliary positioning devices or body markers, such as medical implants, are commonly used…
The interpretation of prostate MRI suffers from low agreement across radiologists due to the subtle differences between cancer and normal tissue. Image registration addresses this issue by accurately mapping the ground-truth cancer labels…
Classical pairwise image registration methods search for a spatial transformation that optimises a numerical measure that indicates how well a pair of moving and fixed images are aligned. Current learning-based registration methods have…