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Spatial Transcriptomics (ST) profiles thousands of gene expression values at discrete spots with precise coordinates on tissue sections, preserving spatial context essential for clinical and pathological studies. With rising sequencing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Yishun Zhu , Jiaxin Qi , Jian Wang , Yuhua Zheng , Jianqiang Huang

This article is intended to supplement our 2015 paper in Medical Physics titled "Noise properties of CT images reconstructed by use of constrained total-variation, data-discrepancy minimization", in which ordered subsets methods were…

Medical Physics · Physics 2016-03-30 Sean Rose , Martin S. Andersen , Emil Y. Sidky , Xiaochuan Pan

Spectral and grating-based differential phase-contrast X-ray imaging are two emerging technologies that offer additional information compared with conventional attenuation-based X-ray imaging. In the case of spectral imaging,…

Medical Physics · Physics 2020-01-31 Korbinian Mechlem , Thorsten Sellerer , Manuel Viermetz , Julia Herzen , Franz Pfeiffer

Spectral computed tomography (CT) offers the possibility to reconstruct attenuation images at different energy levels, which can be then used for material decomposition. However, traditional methods reconstruct each energy bin individually…

Computed Tomography (CT) based precise prostate segmentation for treatment planning is challenging due to (1) the unclear boundary of the prostate derived from CT's poor soft tissue contrast and (2) the limitation of convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2023-07-20 Chengyin Li , Yao Qiang , Rafi Ibn Sultan , Hassan Bagher-Ebadian , Prashant Khanduri , Indrin J. Chetty , Dongxiao Zhu

Reconstructing a 3D Stereo-lithography (STL) Model from 2D Contours of scanned structure in Digital Imaging and Communication in Medicine (DICOM) images is crucial to understand the geometry and deformity. Computed Tomography (CT) images…

Image and Video Processing · Electrical Eng. & Systems 2026-01-22 K. Punnam Chandar , Y. Ravi Kumar

Spectral computed tomography (CT) with photon-counting detectors holds immense potential for material discrimination and tissue characterization. However, under ultra-low-dose conditions, the sharply degraded signal-to-noise ratio (SNR) in…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Peng Peng , Xinrui Zhang , Junlin Wang , Lei Li , Shaoyu Wang , Qiegen Liu

With the advent of neuroimaging and microsurgery, there is a rising need for capturing images through an optical fiber. We present an approach of imaging through a single fiber without mechanical scanning by implementing spatial-spectral…

Optical coherence tomography (OCT) suffers from speckle noise, causing the deterioration of image quality, especially in high-resolution modalities like visible light OCT (vis-OCT). The potential of conventional supervised deep learning…

Image and Video Processing · Electrical Eng. & Systems 2024-05-16 Lingyun Wang , Jose A Sahel , Shaohua Pi

We consider reconstructing multi-channel images from measurements performed by photon-counting and energy-discriminating detectors in the setting of multi-spectral X-ray computed tomography (CT). Our aim is to exploit the strong structural…

Numerical Analysis · Mathematics 2021-03-11 Lukas Kiefer , Stefania Petra , Martin Storath , Andreas Weinmann

Speckle filtering is generally a prerequisite to the analysis of synthetic aperture radar (SAR) images. Tremendous progress has been achieved in the domain of single-image despeckling. Latest techniques rely on deep neural networks to…

Image and Video Processing · Electrical Eng. & Systems 2023-02-08 Inès Meraoumia , Emanuele Dalsasso , Loïc Denis , Rémy Abergel , Florence Tupin

The transmission matrix (TM) is a representation to describe the light scattering process through a scattering medium. The degree of control elements in TM is correlated with the capacity of evaluating enormous equations with tremendous…

Optics · Physics 2020-11-25 Shu Guo , Hao Zhang , Wenxue Li , Lin Pang

Material decomposition in X-ray imaging uses the energy-dependence of attenuation to virtually decompose an object into specific constituent materials. X-ray phase contrast imaging is a developing technique that can enhance image contrast…

This paper proposes a new approach to construct high quality space-filling sample designs. First, we propose a novel technique to quantify the space-filling property and optimally trade-off uniformity and randomness in sample designs in…

Deep learning has demonstrated remarkable achievements in medical image segmentation. However, prevailing deep learning models struggle with poor generalization due to (i) intra-class variations, where the same class appears differently in…

Image and Video Processing · Electrical Eng. & Systems 2024-08-09 Vandan Gorade , Sparsh Mittal , Debesh Jha , Rekha Singhal , Ulas Bagci

Computational spectrometers are at the forefront of spectroscopy, promising portable, on-chip, or in-situ spectrum analysis through the integration of advanced computational techniques into optical systems. However, existing computational…

Optics · Physics 2025-06-19 Yujia Zhang , Chaojun Xu , Zhenyu Zhao , Yikai Su , Xuhan Guo

This paper outlines image domain material decomposition algorithms that have been routinely used in MARS spectral CT systems. These algorithms (known collectively as MARS-MD) are based on a pragmatic heuristic for solving the…

Computational spectrometers are pivotal in enabling low-cost, in-situ and rapid spectral analysis, with potential applications in chemistry, biology, and environmental science. However, filter-based spectral encoding approaches typically…

Semantic Image Segmentation facilitates a multitude of real-world applications ranging from autonomous driving over industrial process supervision to vision aids for human beings. These models are usually trained in a supervised fashion…

Computer Vision and Pattern Recognition · Computer Science 2024-05-22 Volker Knauthe , Arne Rak , Tristan Wirth , Thomas Pöllabauer , Simon Metzler , Arjan Kuijper , Dieter W. Fellner

X-ray Computed Tomography (CT) is one of the most important diagnostic imaging techniques in clinical applications. Sparse-view CT imaging reduces the number of projection views to a lower radiation dose and alleviates the potential risk of…

Image and Video Processing · Electrical Eng. & Systems 2024-11-22 Xiaohong Fan , Ke Chen , Huaming Yi , Yin Yang , Jianping Zhang
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