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Inertial microfluidic devices (IMDs) offer low-cost, high-throughput alternative techniques for many traditional particle- (or cell-) manipulation tasks, but simulating them requires being able to predict particle migration, and thus…

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We show that full-image micro-PIV analysis in combination with images of transient particle motion is a powerful tool for experimental studies of acoustic radiation forces and acoustic streaming in microfluidic chambers under…

Fluid Dynamics · Physics 2012-01-31 S. Melker Sundin , Thomas Glasdam Jensen , Henrik Bruus , Jorg P. Kutter

Acoustic tweezers are gaining increasing attention due to their excellent biological compatibility. Recently, the concept of topology has been expanded from condensed matter physics into acoustics, giving rise to a robust wave manipulation…

Applied Physics · Physics 2021-06-23 Hongqing Dai , Linbo Liu , Baizhan Xia , Dejie Yu

Mixing is one of the basic functions which automated lab-on-chips require for the effective management of liquid samples. In this paper we report on the working principle, design, fabrication and experimental characterization of a…

Soft Condensed Matter · Physics 2010-12-14 M. Campisi , D. Accoto , F. Damiani , P. Dario

Droplets are the core functional units in microfluidic technologies that aim to integrate computation and reaction on a single platform. Achieving directed transport and control of these droplets typically demands elaborate substrate…

Soft Condensed Matter · Physics 2025-10-03 Zixuan Wu , Gavin Linton , Stefan Karpitschka , Anupam Pandey

In this work, we used a coupled level set and volume of fluid (CLSVOF) computational method for studying the generation of microdroplets in a two dimensional circular co-flow microfluidic device. The fundamental understanding of shear…

Fluid Dynamics · Physics 2025-07-17 Manohar Jammula , Somasekhara Goud Sontti

Flow-based microfluidic biochips have attracted much atten- tion in the EDA community due to their miniaturized size and execution efficiency. Previous research, however, still follows the traditional computing model with a dedicated…

Emerging Technologies · Computer Science 2017-05-16 Chunfeng Liu , Bing Li , Hailong Yao , Paul Pop , Tsung-Yi Ho , Ulf Schlichtmann

Recent numerical analyses to optimize the design of microfluidic devices for more effective entrapment or segregation of surrogate circulating tumor cells (CTCs) from healthy cells have been reported in the literature without concurrently…

Computational Physics · Physics 2020-06-23 Hakan Başağaoğlu , Justin Blount , Sauro Succi , Christopher J. Freitas

One of the vital functions of naturally occurring cilia is fluid transport. Biological cilia use spatially asymmetric strokes to generate a net fluid flow that can be utilized for feeding, swimming, and other functions. Biomimetic synthetic…

Fluid Dynamics · Physics 2018-07-19 Srinivas Hanasoge , Peter J. Hesketh , Alexander Alexeev

Incompressible fluids in microfluidic networks with non-rigid channels can exhibit flow rate oscillations analogous to electric current oscillations in RLC circuits. This is due to the elastic deformation of channel walls that can store and…

Fluid Dynamics · Physics 2025-05-08 Yanxuan Shao , Jean-Regis Angilella , Adilson Motter

The micromixing process in microfluidic devices is of central importance in quite a few applications, with microfluidic studies on carbon capture and environmental monitoring being two examples. High surface area to volume ratio in…

Fluid Dynamics · Physics 2025-11-21 Seyed Shahriar Riazi , Seyed Mostafa Hosseinalipour

There is an emerging class of microfluidic bioreactors which possess long-term, closed circuit perfusion under sterile conditions with in vivo-like flow parameters. Integrated into microfluidics, peristaltic-like pneumatically actuated…

Fluid Dynamics · Physics 2017-09-26 T. N. Gerasimenko , O. V. Kindeeva , V. A. Petrov , A. I. Khaustov , E. V. Trushkin

A leading concept in soft robotics actuation, as well as in microfluidics applications such as valves in lab-on-a-chip devices, is applying pressurized flow in cavities embedded within elastic bodies. Generating complex deformation patterns…

Soft Condensed Matter · Physics 2019-03-12 Eran Ben-Haim , Lior Salem , Yizhar Or , Amir D. Gat

Microfluidic droplet screens serve as an innovative platform for high-throughput biotechnology, enabling significant advancements in discovery, product optimization, and analysis. This review sheds light on the emerging trend of interaction…

Quantitative Methods · Quantitative Biology 2023-09-11 Carolus Vitalis , Tobias Wenzel

Polydimethylsiloxane (PDMS) microfluidic devices have become a standard tool for engineering cells and multicellular networks in vitro. However, the reservoirs, or through-holes where cells access the devices, are usually fabricated…

Applied Physics · Physics 2020-12-02 Taiki Takemuro , Hideaki Yamamoto , Shigeo Sato , Ayumi Hirano-Iwata

High-precision micromanipulation techniques, including optical tweezers and hydrodynamic trapping, have garnered wide-spread interest. Recent advances in optofluidic multiplexed assembly and microrobotics demonstrate significant progress,…

Fluid Dynamics · Physics 2025-11-03 Elena Erben , Ivan Saraev , Weida Liao , Fan Nan , Eric Lauga , Moritz Kreysing

Using a previously well-tested numerical model, we demonstrate theoretically that good acoustophoresis can be obtained in a microchannel embedded in an acoustically soft, all-polymer chip, by excitation of whole-system ultrasound…

Fluid Dynamics · Physics 2019-01-16 Rayisa P. Moiseyenko , Henrik Bruus

We demonstrate a fully-integrated multipurpose microwave frequency identification system on silicon-on-insulator platform. Thanks to its multipurpose features, the chip is able to identify different types of microwave signals, including…

Signal Processing · Electrical Eng. & Systems 2022-03-01 Yuhan Yao , Yuhe Zhao , Yanxian Wei , Feng Zhou , Daigao Chen , Yuguang Zhang , Xi Xiao , Ming Li , Jianji Dong , Shaohua Yu , Xinliang Zhang

Frequency combs, specialized laser sources emitting multiple equidistant frequency lines, have revolutionized science and technology with unprecedented precision and versatility. Recently, integrated frequency combs are emerging as scalable…

The emerging field of deformable microfluidics widely employed in the Lab-on-a-Chip and MEMS communities offers an opportunity to study a relatively under-examined physics. The main objective of this work is to provide a deeper insight into…

Fluid Dynamics · Physics 2018-09-14 Aryan Mehboudi , Junghoon Yeom