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In cell biology, statistical analysis means testing the hypothesis that there was no effect. This weak form of hypothesis testing neglects effect size, is universally misinterpreted, and is disastrously prone to error when combined with…

Other Quantitative Biology · Quantitative Biology 2025-05-13 Josh L. Morgan

Nonparametric two sample testing deals with the question of consistently deciding if two distributions are different, given samples from both, without making any parametric assumptions about the form of the distributions. The current…

Statistics Theory · Mathematics 2014-11-25 Aaditya Ramdas , Sashank J. Reddi , Barnabas Poczos , Aarti Singh , Larry Wasserman

When solving NLP tasks with limited labelled data, researchers typically either use a general large language model without further update, or use a small number of labelled samples to tune a specialised smaller model. In this work, we…

Computation and Language · Computer Science 2026-01-26 Branislav Pecher , Ivan Srba , Maria Bielikova

A systematic, comparative investigation into the effects of low-quality data reveals a stark spectrum of robustness across modern probabilistic models. We find that autoregressive language models, from token prediction to…

Artificial Intelligence · Computer Science 2025-12-16 Liu Peng , Yaochu Jin

It is quite common in modern research, for a researcher to test many hypotheses. The statistical (frequentist) hypothesis testing framework, does not scale with the number of hypotheses in the sense that naively performing many hypothesis…

Methodology · Statistics 2013-06-26 Jonathan Rosenblatt

Statistical significance testing is used in natural language processing (NLP) to determine whether the results of a study or experiment are likely to be due to chance or if they reflect a genuine relationship. A key step in significance…

Computation and Language · Computer Science 2024-01-01 Palash Goyal , Qian Hu , Rahul Gupta

Recent work has indicated that many natural language understanding and reasoning datasets contain statistical cues that may be taken advantaged of by NLP models whose capability may thus be grossly overestimated. To discover the potential…

Computation and Language · Computer Science 2021-02-10 Shanshan Huang , Kenny Q. Zhu

This paper studies the validity of nonparametric tests used in the regression discontinuity design. The null hypothesis of interest is that the average treatment effect at the threshold in the so-called sharp design equals a pre-specified…

Methodology · Statistics 2016-11-16 Vishal Kamat

In randomized experiments with noncompliance, tests may focus on compliers rather than on the overall sample. Rubin (1998) put forth such a method, and argued that testing for the complier average causal effect and averaging permutation…

Methodology · Statistics 2016-02-23 Laura Forastiere , Fabrizia Mealli , Luke Miratrix

Critical states are sometimes identified experimentally through power-law statistics or universal scaling functions. We show here that such features naturally emerge from networks in self-sustained irregular regimes away from criticality.…

Neurons and Cognition · Quantitative Biology 2017-02-08 Jonathan Touboul , Alain Destexhe

Two common concerns raised in analyses of randomized experiments are (i) appropriately handling issues of non-compliance, and (ii) appropriately adjusting for multiple tests (e.g., on multiple outcomes or subgroups). Although simple…

Methodology · Statistics 2016-05-25 Joseph J. Lee , Laura Forastiere , Luke Miratrix , Natesh S. Pillai

This article emphasizes that NLP as a science seeks to make inferences about the performance effects that result from applying one method (compared to another method) in the processing of natural language. Yet NLP research in practice…

Computation and Language · Computer Science 2022-09-15 Sandra Wankmüller

The logical and practical difficulties associated with research interpretation using P values and null hypothesis significance testing have been extensively documented. This paper describes an alternative, likelihood-based approach to…

Methodology · Statistics 2021-09-21 Nicholas Adams , Gerard O'Reilly

Increasing accessibility of data to researchers makes it possible to conduct massive amounts of statistical testing. Rather than follow a carefully crafted set of scientific hypotheses with statistical analysis, researchers can now test…

Genomics · Quantitative Biology 2016-09-08 Olga A. Vsevolozhskaya , Chia-Ling Kuo , Gabriel Ruiz , Luda Diatchenko , Dmitri V. Zaykin

Increasingly larger datasets have become a standard ingredient to advancing the state-of-the-art in NLP. However, data quality might have already become the bottleneck to unlock further gains. Given the diversity and the sizes of modern…

Computation and Language · Computer Science 2023-10-18 Irina Bejan , Artem Sokolov , Katja Filippova

Clinical trial design ensures that primary analysis outcomes have strong statistical properties. However, mainstream methodology for randomised study design does not establish a formal link between statistical and clinical significance.…

Applications · Statistics 2026-03-12 Fabio Rigat

We introduce a set of resampling-based methods for quantifying uncertainty and statistical precision of evaluation metrics in multilingual and/or multitask NLP benchmarks. We show how experimental variation in performance scores arises from…

Computation and Language · Computer Science 2025-12-19 Jonne Sälevä , Duygu Ataman , Constantine Lignos

Two semimetrics on probability distributions are proposed, given as the sum of differences of expectations of analytic functions evaluated at spatial or frequency locations (i.e, features). The features are chosen so as to maximize the…

Machine Learning · Statistics 2016-10-31 Wittawat Jitkrittum , Zoltan Szabo , Kacper Chwialkowski , Arthur Gretton

In machine learning, a bias occurs whenever training sets are not representative for the test data, which results in unreliable models. The most common biases in data are arguably class imbalance and covariate shift. In this work, we aim to…

Machine Learning · Computer Science 2018-04-04 Patrick Glauner , Radu State , Petko Valtchev , Diogo Duarte

Genome-wide association analysis has generated much discussion about how to preserve power to detect signals despite the detrimental effect of multiple testing on power. We develop a weighted multiple testing procedure that facilitates the…

Statistics Theory · Mathematics 2007-06-13 Kathryn Roeder , Bernie Devlin , Larry Wasserman
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