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In this work we present a method of automatic segmentation of defective skulls for custom cranial implant design and 3D printing purposes. Since such tissue models are usually required in patient cases with complex anatomical defects and…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Oldřich Kodym , Michal Španěl , Adam Herout

The electron microscope (EM) remains the predominant technique for elucidating intricate details of the animal nervous system at the nanometer scale. However, accurately reconstructing the complex morphology of axons and myelin sheaths…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Ao Cheng , Guoqiang Zhao , Lirong Wang , Ruobing Zhang

Deep cerebellar nuclei are a key structure of the cerebellum that are involved in processing motor and sensory information. It is thus a crucial step to accurately segment deep cerebellar nuclei for the understanding of the cerebellum…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Jinyoung Kim , Remi Patriat , Jordan Kaplan , Oren Solomon , Noam Harel

The hypothalamus plays an important role in the regulation of the bodys metabolic state and behaviors related to survival. Despite its importance however, many questions exist regarding the intrinsic and extrinsic connections of the…

Structural MRI(S-MRI) is one of the most versatile imaging modality that revolutionized the anatomical study of brain in past decades. The corpus callosum (CC) is the principal white matter fibre tract, enabling all kinds of…

Image and Video Processing · Electrical Eng. & Systems 2023-06-02 Vamshi Krishna Kancharla , Debanjali Bhattacharya , Neelam Sinha , Jitender Saini , Pramod Kumar Pal , Sandhya M

Measurements of neuronal activity across brain areas are important for understanding the neural correlates of cognitive and motor processes like attention, decision-making, and action selection. However, techniques that allow cellular…

Skullstripping is defined as the task of segmenting brain tissue from a full head magnetic resonance image~(MRI). It is a critical component in neuroimage processing pipelines. Downstream deformable registration and whole brain segmentation…

Computer Vision and Pattern Recognition · Computer Science 2019-04-30 Amod Jog , P. Ellen Grant , Joseph L. Jacobson , Andre van der Kouwe , Ernesta M. Meintjes , Bruce Fischl , Lilla Zöllei

Endovascular coil embolization is one of the primary treatment techniques for cerebral aneurysms. Although it is a well established and minimally invasive method, it bears the risk of sub-optimal coil placement which can lead to incomplete…

Computational Engineering, Finance, and Science · Computer Science 2024-02-06 Fabian Holzberger , Markus Muhr , Barbara Wohlmuth

Convolutional neural networks (CNNs) have achieved state-of-the-art performance for automatic medical image segmentation. However, they have not demonstrated sufficiently accurate and robust results for clinical use. In addition, they are…

Computer Vision and Pattern Recognition · Computer Science 2018-07-23 Guotai Wang , Wenqi Li , Maria A. Zuluaga , Rosalind Pratt , Premal A. Patel , Michael Aertsen , Tom Doel , Anna L. David , Jan Deprest , Sebastien Ourselin , Tom Vercauteren

Ex vivo MRI of the brain provides remarkable advantages over in vivo MRI for visualizing and characterizing detailed neuroanatomy. However, automated cortical segmentation methods in ex vivo MRI are not well developed, primarily due to…

Cerebral Microbleeds (CMBs) are chronic deposits of small blood products in the brain tissues, which have explicit relation to various cerebrovascular diseases depending on their anatomical location, including cognitive decline,…

Image and Video Processing · Electrical Eng. & Systems 2023-06-27 Jun-Ho Kim , Young Noh , Haejoon Lee , Seul Lee , Woo-Ram Kim , Koung Mi Kang , Eung Yeop Kim , Mohammed A. Al-masni , Dong-Hyun Kim

Segmentation of histological images is one of the most crucial tasks for many biomedical analyses including quantification of certain tissue type. However, challenges are posed by high variability and complexity of structural features in…

Computer Vision and Pattern Recognition · Computer Science 2020-07-30 Xiaohang Fu , Tong Liu , Zhaohan Xiong , Bruce H. Smaill , Martin K. Stiles , Jichao Zhao

Gray matter (GM) tissue changes have been associated with a wide range of neurological disorders and was also recently found relevant as a biomarker for disability in amyotrophic lateral sclerosis. The ability to automatically segment the…

Computer Vision and Pattern Recognition · Computer Science 2018-06-22 Christian S. Perone , Evan Calabrese , Julien Cohen-Adad

We propose a novel method that combines a convolutional neural network (CNN) with a long short-term memory (LSTM) mechanism for accurate prediction of intracranial hemorrhage on computed tomography (CT) scans. The CNN plays the role of a…

Computer Vision and Pattern Recognition · Computer Science 2020-06-29 Nhan T. Nguyen , Dat Q. Tran , Nghia T. Nguyen , Ha Q. Nguyen

Human brain anatomy and function display a combination of modular and hierarchical organization, suggesting the importance of both cohesive structures and variable resolutions in the facilitation of healthy cognitive processes. However,…

Neurons and Cognition · Quantitative Biology 2015-06-18 Christian Lohse , Danielle S. Bassett , Kelvin O. Lim , Jean M. Carlson

Ischaemic stroke is a medical condition caused by occlusion of blood supply to the brain tissue thus forming a lesion. A lesion is zoned into a core associated with irreversible necrosis typically located at the center of the lesion, while…

Image and Video Processing · Electrical Eng. & Systems 2019-08-06 Rachana Sathish , Ronnie Rajan , Anusha Vupputuri , Nirmalya Ghosh , Debdoot Sheet

Segmenting a structural magnetic resonance imaging (MRI) scan is an important pre-processing step for analytic procedures and subsequent inferences about longitudinal tissue changes. Manual segmentation defines the current gold standard in…

Computer Vision and Pattern Recognition · Computer Science 2017-06-07 Alex Fedorov , Jeremy Johnson , Eswar Damaraju , Alexei Ozerin , Vince Calhoun , Sergey Plis

The thalamus consists of several histologically and functionally distinct nuclei increasingly implicated in brain pathology and important for treatment, motivating the need for development of fast and accurate thalamic segmentation. The…

Image and Video Processing · Electrical Eng. & Systems 2019-12-19 Charles Iglehart , Martin Monti , Joshua Cain , Thomas Tourdias , Manojkumar Saranathan

To characterize lobar and segmental airway volume differences between systemic lupus erythematosus (SLE) patients with interstitial lung disease (ILD) and those without ILD (non-ILD) using a deep learning-based approach on non-contrast…

Image and Video Processing · Electrical Eng. & Systems 2026-03-19 Sirong Piao , Ying Ming , Ruijie Zhao , Jiaru Wang , Ran Xiao , Rui Zhao , Zicheng Liao , Qiqi Xu , Shaoze Luo , Bing Li , Lin Li , Zhuangfei Ma , Fuling Zheng , Wei Song