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Related papers: BioMegatron: Larger Biomedical Domain Language Mod…

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The primary aim of this research was to address the limitations observed in the medical knowledge of prevalent large language models (LLMs) such as ChatGPT, by creating a specialized language model with enhanced accuracy in medical advice.…

Computation and Language · Computer Science 2023-06-27 Yunxiang Li , Zihan Li , Kai Zhang , Ruilong Dan , Steve Jiang , You Zhang

Models such as GPT-4 and Med-PaLM 2 have demonstrated impressive performance on a wide variety of biomedical NLP tasks. However, these models have hundreds of billions of parameters, are computationally expensive to run, require users to…

This study aims to guide language model selection by investigating: 1) the necessity of finetuning versus zero-shot usage, 2) the benefits of domain-adjacent versus generic pretrained models, 3) the value of further domain-specific…

Computation and Language · Computer Science 2025-09-25 Lovedeep Gondara , Jonathan Simkin , Graham Sayle , Shebnum Devji , Gregory Arbour , Raymond Ng

Several biomedical language models have already been developed for clinical language inference. However, these models typically utilize general vocabularies and are trained on relatively small clinical corpora. We sought to evaluate the…

Computation and Language · Computer Science 2022-10-14 Madhumita Sushil , Dana Ludwig , Atul J. Butte , Vivek A. Rudrapatna

There is growing interest in the automated extraction of relevant information from clinical dialogues. However, it is difficult to collect and construct large annotated resources for clinical dialogue tasks. Recent developments in natural…

Computation and Language · Computer Science 2022-06-07 Zhengyuan Liu , Pavitra Krishnaswamy , Nancy F. Chen

Large Language Models (LLMs), particularly those similar to ChatGPT, have significantly influenced the field of Natural Language Processing (NLP). While these models excel in general language tasks, their performance in domain-specific…

Computation and Language · Computer Science 2024-01-02 Omid Rohanian , Mohammadmahdi Nouriborji , David A. Clifton

Contextualized word embeddings derived from pre-trained language models (LMs) show significant improvements on downstream NLP tasks. Pre-training on domain-specific corpora, such as biomedical articles, further improves their performance.…

Computation and Language · Computer Science 2019-04-05 Qiao Jin , Bhuwan Dhingra , William W. Cohen , Xinghua Lu

Large Language Models (LLMs) have demonstrated remarkable versatility in recent years, offering potential applications across specialized domains such as healthcare and medicine. Despite the availability of various open-source LLMs tailored…

Computation and Language · Computer Science 2024-07-18 Yanis Labrak , Adrien Bazoge , Emmanuel Morin , Pierre-Antoine Gourraud , Mickael Rouvier , Richard Dufour

The overwhelming amount of biomedical scientific texts calls for the development of effective language models able to tackle a wide range of biomedical natural language processing (NLP) tasks. The most recent dominant approaches are…

Computation and Language · Computer Science 2021-04-21 Giacomo Miolo , Giulio Mantoan , Carlotta Orsenigo

Research on language technology for the development of medical applications is currently a hot topic in Natural Language Understanding and Generation. Thus, a number of large language models (LLMs) have recently been adapted to the medical…

In recent years, pre-trained language models (PLMs) achieve the best performance on a wide range of natural language processing (NLP) tasks. While the first models were trained on general domain data, specialized ones have emerged to more…

Computation and Language · Computer Science 2023-05-08 Yanis Labrak , Adrien Bazoge , Richard Dufour , Mickael Rouvier , Emmanuel Morin , Béatrice Daille , Pierre-Antoine Gourraud

Adapting general multimodal large language models (MLLMs) to specific domains, such as scientific and industrial fields, is highly significant in promoting their practical applications. This paper systematically investigates domain…

Computation and Language · Computer Science 2025-08-28 Daixuan Cheng , Shaohan Huang , Ziyu Zhu , Xintong Zhang , Wayne Xin Zhao , Zhongzhi Luan , Bo Dai , Zhenliang Zhang

There are many cases where LLMs are used for specific tasks in a single domain. These usually require less general, but more domain-specific knowledge. Highly capable, general-purpose state-of-the-art language models like GPT-4 or…

Machine Learning · Computer Science 2024-07-30 Tobias Kerner

This paper conducts a comprehensive investigation into applying large language models, particularly on BioBERT, in healthcare. It begins with thoroughly examining previous natural language processing (NLP) approaches in healthcare, shedding…

Artificial Intelligence · Computer Science 2023-10-13 Shyni Sharaf , V. S. Anoop

Pre-training and fine-tuning have emerged as a promising paradigm across various natural language processing (NLP) tasks. The effectiveness of pretrained large language models (LLM) has witnessed further enhancement, holding potential for…

Computation and Language · Computer Science 2023-11-06 Guoxing Yang , Jianyu Shi , Zan Wang , Xiaohong Liu , Guangyu Wang

The exponential growth of online textual content across diverse domains has necessitated advanced methods for automated text classification. Large Language Models (LLMs) based on transformer architectures have shown significant success in…

Computation and Language · Computer Science 2025-09-09 Zhyar Rzgar K Rostam , Gábor Kertész

Biomedical text mining is becoming increasingly important as the number of biomedical documents rapidly grows. With the progress in natural language processing (NLP), extracting valuable information from biomedical literature has gained…

Computation and Language · Computer Science 2019-10-21 Jinhyuk Lee , Wonjin Yoon , Sungdong Kim , Donghyeon Kim , Sunkyu Kim , Chan Ho So , Jaewoo Kang

Large Transformer-based language models are pre-trained on corpora of varying sizes, for a different number of steps and with different batch sizes. At the same time, more fundamental components, such as the pre-training objective or…

Computation and Language · Computer Science 2021-05-12 M. Aßenmacher , P. Schulze , C. Heumann

Large language models (LLMs) can potentially democratize access to medical knowledge. While many efforts have been made to harness and improve LLMs' medical knowledge and reasoning capacities, the resulting models are either closed-source…

Background and Objective: Biomedical Named Entity Recognition (BioNER) is a foundational task in medical informatics, crucial for downstream applications like drug discovery and clinical trial matching. However, adapting general-domain…

Computation and Language · Computer Science 2025-12-30 Jian Chen , Leilei Su , Cong Sun