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Microbes can affect processes from food production to human health. Such microbes are not isolated, but rather interact with each other and establish connections with their living environments. Understanding these interactions is essential…

Applications · Statistics 2021-09-07 Liang Chen , Qiuyan He , Hui Wan , Shun He , Minghua Deng

Microbial networks, representing microbes as nodes and their interactions as edges, are crucial for understanding community dynamics in various environments. Analyzing microbiome networks is crucial for identifying keystone taxa that play…

Molecular Networks · Quantitative Biology 2025-07-15 Qiyao Yang , Rosa Aghdam , Reed Nelson , Claudia Solís-Lemus

Microbial communities are diverse biological systems that include taxa from across multiple kingdoms of life. Notably, interactions between bacteria and fungi play a significant role in determining community structure. However, these…

Quantitative Methods · Quantitative Biology 2024-04-15 James D. Brunner , Aaron J. Robinson , Patrick S. G. Chain

The inference of the interactions between organisms in an ecosystem from observational data is an important problem in ecology. This paper presents a mathematical inference method, originally developed for the inference of biochemical…

Populations and Evolution · Quantitative Biology 2008-05-12 Paola Vera-Licona , Reinhard Laubenbacher

Microbial communities assemble through a complex set of interactions between microbes and their environment, and the resulting metabolic impact on the host ecosystem can be profound. Microbial activity is known to impact human health, plant…

Quantitative Methods · Quantitative Biology 2023-11-09 James D. Brunner , Laverne A. Gallegos-Graves , Marie E. Kroeger

Any network studied in the literature is inevitably just a sampled representative of its real-world analogue. Additionally, network sampling is lately often applied to large networks to allow for their faster and more efficient analysis.…

Social and Information Networks · Computer Science 2015-04-14 Neli Blagus , Lovro Šubelj , Gregor Weiss , Marko Bajec

Networks represent relationships between entities in many complex systems, spanning from online social interactions to biological cell development and brain connectivity. In many cases, relationships between entities are unambiguously…

Social and Information Networks · Computer Science 2018-01-23 Ivan Brugere , Brian Gallagher , Tanya Y. Berger-Wolf

The structure of ecological interactions is commonly understood through analyses of interaction networks. However, these analyses may be sensitive to sampling biases in both the interactors (the nodes of the network) and interactions (the…

Network models are widely used to represent relational information among interacting units and the structural implications of these relations. Recently, social network studies have focused a great deal of attention on random graph models of…

Applications · Statistics 2010-10-06 Mark S. Handcock , Krista J. Gile

The human body consists of microbiomes associated with the development and prevention of several diseases. These microbial organisms form several complex interactions that are informative to the scientific community for explaining disease…

Methodology · Statistics 2024-04-16 Tejasv Bedi , Bencong Zhu , Michael L. Neugent , Kevin C. Lutz , Nicole J. De Nisco , Qiwei Li

Large-scale perturbations in the microbiome constitution are strongly correlated, whether as a driver or a consequence, with the health and functioning of human physiology. However, understanding the difference in the microbiome profiles of…

Quantitative Methods · Quantitative Biology 2022-09-08 Kateryna Melnyk , Kuba Weimann , Tim O. F. Conrad

Understanding the dependence and interplay between architecture and function in biological networks has great relevance to disease progression, biological fabrication and biological systems in general. We propose methods to assess the…

Quantitative Methods · Quantitative Biology 2009-10-17 Soumen Roy , Vladimir Filkov

Complex systems are often characterized by distinct types of interactions between the same entities. These can be described as a multilayer network where each layer represents one type of interaction. These layers may be interdependent in…

Social and Information Networks · Computer Science 2018-08-21 Caterina De Bacco , Eleanor A. Power , Daniel B. Larremore , Cristopher Moore

Community detection is considered as a fundamental task in analyzing social networks. Even though many techniques have been proposed for community detection, most of them are based exclusively on the connectivity structures. However, there…

Social and Information Networks · Computer Science 2019-12-25 Hadi Zare , Mahdi Hajiabadi , Mahdi Jalili

An active area of research interest is the inference of ecological models of complex microbial communities. Inferring such ecological models entails understanding the interactions between microbes and how they affect each other's growth.…

Applications · Statistics 2022-10-19 William Krinsman

Networks are widely used in the biological, physical, and social sciences as a concise mathematical representation of the topology of systems of interacting components. Understanding the structure of these networks is one of the outstanding…

Data Analysis, Statistics and Probability · Physics 2007-06-21 M. E. J. Newman , E. A. Leicht

The behavior of ecological systems mainly relies on the interactions between the species it involves. We consider the problem of inferring the species interaction network from abundance data. To be relevant, any network inference…

Applications · Statistics 2019-10-29 Raphaëlle Momal , Stéphane Robin , Christophe Ambroise

Networks built to model real world phenomena are characeterised by some properties that have attracted the attention of the scientific community: (i) they are organised according to community structure and (ii) their structure evolves with…

Social and Information Networks · Computer Science 2019-09-04 Giulio Rossetti , Rémy Cazabet

A wide range of complex systems can be modeled as networks with corresponding constraints on the edges and nodes, which have been extensively studied in recent years. Nowadays, with the progress of information technology, systems that…

Physics and Society · Physics 2016-05-24 Han Zhang , Chang-Dong Wang , Jian-Huang Lai , Philip S. Yu

Our work is motivated by and illustrated with application of association networks in computational biology, specifically in the context of gene/protein regulatory networks. Association networks represent systems of interacting elements,…

Applications · Statistics 2012-05-01 Natallia Katenka , Eric D. Kolaczyk
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