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Recent advances in single cell sequencing and multi-omics techniques have significantly improved our understanding of biological phenomena and our capacity to model them. Despite combined capture of data modalities showing similar progress,…

Molecular Networks · Quantitative Biology 2025-03-13 Marcello Barylli , Joyaditya Saha , Tineke E. Buffart , Jan Koster , Kristiaan J. Lenos , Louis Vermeulen , Vivek M. Sheraton

Causal reasoning can be considered a cornerstone of intelligent systems. Having access to an underlying causal graph comes with the promise of cause-effect estimation and the identification of efficient and safe interventions. However,…

Machine Learning · Computer Science 2023-11-10 Amir Mohammad Karimi Mamaghan , Andrea Dittadi , Stefan Bauer , Karl Henrik Johansson , Francesco Quinzan

We propose a Bayesian regression method that accounts for multi-way interactions of arbitrary orders among the predictor variables. Our model makes use of a factorization mechanism for representing the regression coefficients of…

Machine Learning · Statistics 2017-09-28 Mikhail Yurochkin , XuanLong Nguyen , Nikolaos Vasiloglou

Bi-clustering is a useful approach in analyzing biological data when observations come from heterogeneous groups and have a large number of features. We outline a general Bayesian approach in tackling bi-clustering problems in moderate to…

Applications · Statistics 2021-02-11 Han Yan , Jiexing Wu , Yang Li , Jun S. Liu

Advanced deep learning (DL) algorithms may predict the patient's risk of developing breast cancer based on the Breast Imaging Reporting and Data System (BI-RADS) and density standards. Recent studies have suggested that the combination of…

Image and Video Processing · Electrical Eng. & Systems 2022-04-19 Huyen T. X. Nguyen , Sam B. Tran , Dung B. Nguyen , Hieu H. Pham , Ha Q. Nguyen

Classification of human emotions can play an essential role in the design and improvement of human-machine systems. While individual biological signals such as Electrocardiogram (ECG) and Electrodermal Activity (EDA) have been widely used…

Machine Learning · Computer Science 2021-08-06 Anubhav Bhatti , Behnam Behinaein , Dirk Rodenburg , Paul Hungler , Ali Etemad

The need for multimodal data integration arises naturally when multiple complementary sets of features are measured on the same sample. Under a dependent multifactor model, we develop a fully data-driven orchestrated approximate message…

Methodology · Statistics 2026-01-22 Sagnik Nandy , Zongming Ma

Regression models are used for inference and prediction in a wide range of applications providing a powerful scientific tool for researchers and analysts from different fields. In many research fields the amount of available data as well as…

Methodology · Statistics 2018-06-08 Aliaksandr Hubin , Geir Storvik , Florian Frommlet

Multimodal learning has mainly focused on learning large models on, and fusing feature representations from, different modalities for better performances on downstream tasks. In this work, we take a detour from this trend and study the…

Computer Vision and Pattern Recognition · Computer Science 2023-05-08 Yifeng Shi , Marc Niethammer

Multimodal deep learning has been used to predict clinical endpoints and diagnoses from clinical routine data. However, these models suffer from scaling issues: they have to learn pairwise interactions between each piece of information in…

Integrative analyses based on statistically relevant associations between genomics and a wealth of intermediary phenotypes (such as imaging) provide vital insights into their clinical relevance in terms of the disease mechanisms. Estimates…

Applications · Statistics 2022-08-16 Snigdha Panigrahi , Shariq Mohammed , Arvind Rao , Veerabhadran Baladandayuthapani

Combining different modalities of data from human tissues has been critical in advancing biomedical research and personalised medical care. In this study, we leverage a graph embedding model (i.e VGAE) to perform link prediction on…

Genomics · Quantitative Biology 2021-07-27 Amine Amor , Pietro Lio' , Vikash Singh , Ramon Viñas Torné , Helena Andres Terre

Bayesian optimisation is a popular technique for hyperparameter learning but typically requires initial exploration even in cases where similar prior tasks have been solved. We propose to transfer information across tasks using learnt…

Machine Learning · Statistics 2019-05-28 Ho Chung Leon Law , Peilin Zhao , Lucian Chan , Junzhou Huang , Dino Sejdinovic

Our interest is in multiplex network data with multiple network samples observed across the same set of nodes. Examples originate from a variety of fields, including brain connectivity, international trade networks, and social networks,…

Methodology · Statistics 2026-04-21 Yuren Zhou , Yuqi Gu , David B. Dunson

How can we effectively encode evolving information over dynamic graphs into low-dimensional representations? In this paper, we propose DyRep, an inductive deep representation learning framework that learns a set of functions to efficiently…

Machine Learning · Computer Science 2018-03-20 Rakshit Trivedi , Mehrdad Farajtabar , Prasenjeet Biswal , Hongyuan Zha

Multi-Instance Learning(MIL) aims to learn the mapping between a bag of instances and the bag-level label. Therefore, the relationships among instances are very important for learning the mapping. In this paper, we propose an MIL algorithm…

Machine Learning · Computer Science 2021-02-04 Yangling Ma , Zhouwang Yang

Molecular property prediction refers to the task of labeling molecules with some biochemical properties, playing a pivotal role in the drug discovery and design process. Recently, with the advancement of machine learning, deep…

Molecular Networks · Quantitative Biology 2024-01-10 Zeyu Wang , Tianyi Jiang , Jinhuan Wang , Qi Xuan

In this paper, an innovative multi-modal deep learning model is proposed to deeply integrate heterogeneous information from medical images and clinical reports. First, for medical images, convolutional neural networks were used to extract…

Machine Learning · Computer Science 2024-05-29 Ziyan Yao , Fei Lin , Sheng Chai , Weijie He , Lu Dai , Xinghui Fei

Causal representation learning (CRL) seeks to uncover meaningful latent variables and their corresponding causal structure from high-dimensional observational data. Although its significance, CRL identifiability remains a crucial property,…

Machine Learning · Computer Science 2026-05-20 Manal Benhamza , Marianne Clausel , Myriam Tami

In recent years, a comprehensive study of multi-view datasets (e.g., multi-omics and imaging scans) has been a focus and forefront in biomedical research. State-of-the-art biomedical technologies are enabling us to collect multi-view…

Machine Learning · Statistics 2020-04-30 Md Ashad Alam , Chuan Qiu , Hui Shen , Yu-Ping Wang , Hong-Wen Deng