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Generative models have shown great promise in generating 3D geometric systems, which is a fundamental problem in many natural science domains such as molecule and protein design. However, existing approaches only operate on static…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 Jiaqi Han , Minkai Xu , Aaron Lou , Haotian Ye , Stefano Ermon

The generalization of neural networks is a central challenge in machine learning, especially concerning the performance under distributions that differ from training ones. Current methods, mainly based on the data-driven paradigm such as…

Machine Learning · Computer Science 2023-12-18 Yige Yuan , Bingbing Xu , Bo Lin , Liang Hou , Fei Sun , Huawei Shen , Xueqi Cheng

We study the distribution of first passage time (FPT) in Levy type of anomalous diffusion. Using recently formulated fractional Fokker-Planck equation we obtain three results. (1) We derive an explicit expression for the FPT distribution in…

Statistical Mechanics · Physics 2009-11-07 Govindan Rangarajan , Mingzhou Ding

We propose two methods for computing the large deviations of the first-passage-time statistics in general open quantum systems. The first method determines the region of convergence of the joint Laplace transform and the $z$-transform of…

Statistical Mechanics · Physics 2026-02-25 Fei Liu , Jiayin Gu

In recent years, a plethora of methods combining deep neural networks and partial differential equations have been developed. A widely known and popular example are physics-informed neural networks. They solve forward and inverse problems…

Optimization and Control · Mathematics 2022-07-04 Bastian Zapf , Johannes Haubner , Miroslav Kuchta , Geir Ringstad , Per Kristian Eide , Kent-Andre Mardal

Diffusion models (DMs) excel in unconditional generation, as well as on applications such as image editing and restoration. The success of DMs lies in the iterative nature of diffusion: diffusion breaks down the complex process of mapping…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Beomsu Kim , Jaemin Kim , Jeongsol Kim , Jong Chul Ye

A rapidly increasing number of systems is identified in which the stochastic motion of tracer particles follows the Brownian law $\langle\mathbf{r}^2(t) \rangle\simeq Dt$ yet the distribution of particle displacements is strongly…

Statistical Mechanics · Physics 2019-01-30 V. Sposini , A. V. Chechkin , R. Metzler

The Schr\"odinger integral-equation approach for calculating the classical first-passage time (C-fpt) probability density is extended to the case of quantum first-passage time (Q-fpt). Using this extension, we have calculated analytically…

Quantum Physics · Physics 2013-06-10 Ranjith V. , N. Kumar

We present a package to simulate long-term diffusive mass transport in systems with atomic scale resolution. The implemented framework is based on a non-equilibrium statistical thermo-chemo-mechanical formulation of atomic systems where…

Computational Physics · Physics 2019-10-04 Juan Pedro Mendez , Mauricio Ponga

This work is concerned with the propagation of uncertainty across coupled domain problems with high-dimensional random inputs. A stochastic model reduction approach based on low-rank separated representations is proposed for the partitioned…

Probability · Mathematics 2015-06-16 Mohammad Hadigol , Alireza Doostan , Hermann G. Matthies , Rainer Niekamp

Gaussian Mixture Models (GMMs) are one of the most potent parametric density models used extensively in many applications. Flexibly-tied factorization of the covariance matrices in GMMs is a powerful approach for coping with the challenges…

Machine Learning · Computer Science 2023-11-14 Mohammad Pasande , Reshad Hosseini , Babak Nadjar Araabi

Density-functional perturbation theory (DFPT) is nowadays the method of choice for the accurate computation of linear and non-linear response properties of materials from first principles. A notable advantage of DFPT over alternative…

Materials Science · Physics 2019-06-19 Miquel Royo , Massimiliano Stengel

Many chemical reactions can be formulated in terms of particle diffusion in a complex energy landscape. Transition path theory (TPT) is a theoretical framework for describing the direct (reaction) pathways from reactant to product states…

Statistical Mechanics · Physics 2023-10-03 Paul C Bressloff

The mean first passage time (MFPT) is a key metric for understanding transport, search, and escape processes in stochastic systems. While well characterized for passive Brownian particles, its behavior in active systems-such as active…

Soft Condensed Matter · Physics 2025-10-22 Sarafa A. Iyaniwura , Zhiwei Peng

The diffusion of molecules in complex intracellular environments can be strongly influenced by spatial heterogeneity and stochasticity. A key challenge when modelling such processes using stochastic random walk frameworks is that negative…

Biological Physics · Physics 2019-01-31 Elliot J. Carr , Matthew J. Simpson

Multiscale spatial structure complicates temporal prediction because small-scale spatial fluctuations influence large-scale evolution, yet resolving all scales is often intractable. Standard diffusion models do not address this problem…

Fluid Dynamics · Physics 2026-04-02 Yuki Yasuda , Tobias Bischoff

For transport processes in geometrically restricted domains, the mean first-passage time (MFPT) admits a general scaling dependence on space parameters for diffusion, anomalous diffusion, and diffusion in disordered or fractal media. For…

Statistical Mechanics · Physics 2015-06-05 Eric Akkermans , Olivier Benichou , Gerald Dunne , Alexander Teplyaev , Raphael Voituriez

We introduce a unified framework for solving first passage times of time-homogeneous diffusion processes. According to the killed version potential theory and the perturbation theory, we are able to deduce closed-form solutions for…

Probability · Mathematics 2026-01-14 Angelos Dassios , Luting Li

Interesting theoretical problems of target search or threshold crossing, formally known as {\it first passage}, often arise in both diffusive transport problems as well as problems of chemical reaction kinetics. We study three systems…

Statistical Mechanics · Physics 2025-10-22 Hillol Kumar Barman , Pathik Das , Syed Yunus Ali

Irregular distribution in latent space causes posterior collapse, misalignment between posterior and prior, and ill-sampling problem in Variational Autoencoders (VAEs). In this paper, we introduce a novel adaptable three-stage Uniform…

Machine Learning · Computer Science 2024-07-04 Ye Shi , C. S. George Lee
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