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Cluster analysis aims at separating patients into phenotypically heterogenous groups and defining therapeutically homogeneous patient subclasses. It is an important approach in data-driven disease classification and subtyping. Acute…

Quantitative Methods · Quantitative Biology 2019-03-28 Eryu Xia , Xin Du , Jing Mei , Wen Sun , Suijun Tong , Zhiqing Kang , Jian Sheng , Jian Li , Changsheng Ma , Jianzeng Dong , Shaochun Li

We propose a CNN based technique that aggregates feature maps from its multiple layers that can localize abnormalities with greater details as well as predict pathology under consideration. Existing class activation mapping (CAM) techniques…

Computer Vision and Pattern Recognition · Computer Science 2019-10-01 Sumeet Shinde , Tanay Chougule , Jitender Saini , Madhura Ingalhalikar

This paper demonstrates a novel and efficient unsupervised clustering method with the combination of a Self-Organising Map (SOM) and a convolutional autoencoder. The rapidly increasing volume of radio-astronomical data has increased demand…

Medical imaging is an essential tool in many areas of medical applications, used for both diagnosis and treatment. However, reading medical images and making diagnosis or treatment recommendations require specially trained medical…

Computer Vision and Pattern Recognition · Computer Science 2019-03-13 Wentao Zhu

Estimating the number of clusters and cluster structures in unlabeled, complex, and high-dimensional datasets (like images) is challenging for traditional clustering algorithms. In recent years, a matrix reordering-based algorithm called…

Clustering algorithms have significantly improved along with Deep Neural Networks which provide effective representation of data. Existing methods are built upon deep autoencoder and self-training process that leverages the distribution of…

Computer Vision and Pattern Recognition · Computer Science 2021-09-17 Xin Ma , Won Hwa Kim

AI-enabled precision medicine promises a transformational improvement in healthcare outcomes by enabling data-driven personalized diagnosis, prognosis, and treatment. However, the well-known "curse of dimensionality" and the clustered…

Machine Learning · Computer Science 2023-05-19 Amanda M. Buch , Conor Liston , Logan Grosenick

Recent advancements in foundation models, such as the Segment Anything Model (SAM), have significantly impacted medical image segmentation, especially in retinal imaging, where precise segmentation is vital for diagnosis. Despite this…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Zhihao Zhao , Yinzheng Zhao , Junjie Yang , Xiangtong Yao , Quanmin Liang , Shahrooz Faghihroohi , Kai Huang , Nassir Navab , M. Ali Nasseri

Clustering algorithms are often used to find subpopulations in exploratory data analysis workflows. Not only the clusters themselves, but also their shape can represent meaningful subpopulations. In this paper, we present FLASC, an…

Machine Learning · Computer Science 2025-04-23 D. M. Bot , J. Peeters , J. Liesenborgs , J. Aerts

Sparse learning has been shown to be effective in solving many real-world problems. Finding sparse representations is a fundamentally important topic in many fields of science including signal processing, computer vision, genome study and…

Computer Vision and Pattern Recognition · Computer Science 2018-07-30 Jun Cheng

Anomaly and outlier detection is a long-standing problem in machine learning. In some cases, anomaly detection is easy, such as when data are drawn from well-characterized distributions such as the Gaussian. However, when data occupy…

Machine Learning · Computer Science 2021-11-24 Najib Ishaq , Thomas J. Howard , Noah M. Daniels

With the ongoing COVID-19 pandemic, understanding the characteristics of the virus has become an important and challenging task in the scientific community. While tests do exist for COVID-19, the goal of our research is to explore other…

Computer Vision and Pattern Recognition · Computer Science 2021-12-02 Jacob Householder , Andrew Householder , John Paul Gomez-Reed , Fredrick Park , Shuai Zhang

Generating interpretable visualizations from complex data is a common problem in many applications. Two key ingredients for tackling this issue are clustering and representation learning. However, current methods do not yet successfully…

Machine Learning · Computer Science 2020-06-11 Laura Manduchi , Matthias Hüser , Julia Vogt , Gunnar Rätsch , Vincent Fortuin

Median clustering extends popular neural data analysis methods such as the self-organizing map or neural gas to general data structures given by a dissimilarity matrix only. This offers flexible and robust global data inspection methods…

Machine Learning · Computer Science 2009-09-04 Barbara Hammer , Alexander Hasenfuß , Fabrice Rossi

Background: As available medical image datasets increase in size, it becomes infeasible for clinicians to review content manually for knowledge extraction. The objective of this study was to create an automated clustering resulting in…

Computer Vision and Pattern Recognition · Computer Science 2023-09-18 Lidia Talavera-Martinez , Philipp Tschandl

The class activation mapping, or CAM, has been the cornerstone of feature attribution methods for multiple vision tasks. Its simplicity and effectiveness have led to wide applications in the explanation of visual predictions and…

Computer Vision and Pattern Recognition · Computer Science 2021-08-13 Jae Myung Kim , Junsuk Choe , Zeynep Akata , Seong Joon Oh

Clustering is central to many data-driven application domains and has been studied extensively in terms of distance functions and grouping algorithms. Relatively little work has focused on learning representations for clustering. In this…

Machine Learning · Computer Science 2016-05-26 Junyuan Xie , Ross Girshick , Ali Farhadi

Clustering is a fundamental unsupervised learning approach. Many clustering algorithms -- such as $k$-means -- rely on the euclidean distance as a similarity measure, which is often not the most relevant metric for high dimensional data…

Machine Learning · Computer Science 2019-10-22 Aude Genevay , Gabriel Dulac-Arnold , Jean-Philippe Vert

In many applications of X-ray computed tomography, an unsupervised segmentation of the reconstructed 3D volumes forms an important step in the image processing chain for further investigation of the digitized object. Therefore, the goal is…

Computer Vision and Pattern Recognition · Computer Science 2023-03-09 Thomas Lang

Image clustering is a very useful technique that is widely applied to various areas, including remote sensing. Recently, visual representations by self-supervised learning have greatly improved the performance of image clustering. To…

Computer Vision and Pattern Recognition · Computer Science 2022-09-27 Qinglin Li , Guoping Qiu