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Understanding the basic operational logics of the nervous system is essential to advancing neuroscientific research. However, theoretical efforts to tackle this fundamental problem are lacking, despite the abundant empirical data about the…

Neurons and Cognition · Quantitative Biology 2021-09-07 Cheng Qian

Causal relations among neuronal populations of the brain are studied through the so-called effective connectivity (EC) network. The latter is estimated from EEG or fMRI measurements, by inverting a generative model of the corresponding…

Systems and Control · Computer Science 2018-02-16 Giulia Prando , Mattia Zorzi , Alessandra Bertoldo , Alessandro Chiuso

Inference of causality is central in nonlinear time series analysis and science in general. A popular approach to infer causality between two processes is to measure the information flow between them in terms of transfer entropy. Using…

Chaotic Dynamics · Physics 2015-04-16 Jie Sun , Erik M. Bollt

Learning the structure of a causal graphical model using both observational and interventional data is a fundamental problem in many scientific fields. A promising direction is continuous optimization for score-based methods, which,…

Machine Learning · Computer Science 2022-02-28 Phillip Lippe , Taco Cohen , Efstratios Gavves

Neural circuit reconstruction at single synapse resolution is increasingly recognized as crucially important to decipher the function of biological nervous systems. Volume electron microscopy in serial transmission or scanning mode has been…

Computer Vision and Pattern Recognition · Computer Science 2018-05-09 Larissa Heinrich , Jan Funke , Constantin Pape , Juan Nunez-Iglesias , Stephan Saalfeld

Synaptic plasticity dynamically shapes the connectivity of neural systems and is key to learning processes in the brain. To what extent the mechanisms of plasticity can be exploited to drive a neural network and make it perform some kind of…

Neurons and Cognition · Quantitative Biology 2024-12-03 Francesco Borra , Simona Cocco , Rémi Monasson

Neurophysiologists are nowadays able to record from a large number of extracellular electrodes and to extract, from the raw data, the sequences of action potentials or spikes generated by many neurons. Unfortunately these ''many neurons''…

Applications · Statistics 2026-04-22 Pierre Charitat , Ségolen Geffray , Christophe Pouzat

Connectomics and network neuroscience offer quantitative scientific frameworks for modeling and analyzing networks of structurally and functionally interacting neurons, neuronal populations, and macroscopic brain areas. This shift in…

Neurons and Cognition · Quantitative Biology 2020-10-06 Richard Betzel

Transient phenomena play a key role in coordinating brain activity at multiple scales, however,their underlying mechanisms remain largely unknown. A key challenge for neural data science is thus to characterize the network interactions at…

Neurons and Cognition · Quantitative Biology 2022-09-16 Kaidi Shao , Nikos K. Logothetis , Michel Besserve

The neural mechanism of memory has a very close relation with the problem of representation in artificial intelligence. In this paper a computational model was proposed to simulate the network of neurons in brain and how they process…

Neurons and Cognition · Quantitative Biology 2020-12-02 Hui Wei

Intrinsic computation refers to how dynamical systems store, structure, and transform historical and spatial information. By graphing a measure of structural complexity against a measure of randomness, complexity-entropy diagrams display…

Chaotic Dynamics · Physics 2009-11-13 David P. Feldman , Carl S. McTague , James P. Crutchfield

Deep learning has seen remarkable developments over the last years, many of them inspired by neuroscience. However, the main learning mechanism behind these advances - error backpropagation - appears to be at odds with neurobiology. Here,…

Neurons and Cognition · Quantitative Biology 2018-10-29 João Sacramento , Rui Ponte Costa , Yoshua Bengio , Walter Senn

Neural computation is associated with the emergence, reconfiguration and dissolution of cell assemblies in the context of varying oscillatory states. Here, we describe the complex spatio-temporal dynamics of cell assemblies through temporal…

Neurons and Cognition · Quantitative Biology 2020-01-20 Nicola Pedreschi , Christophe Bernard , Wesley Clawson , Pascale Quilichini , Alain Barrat , Demian Battaglia

This paper describes a new entropy-style of equation that may be useful in a general sense, but can be applied to a cognitive model with related processes. The model is based on the human brain, with automatic and distributed pattern…

Artificial Intelligence · Computer Science 2021-04-23 Kieran Greer

Dimensionality reduction, a form of compression, can simplify representations of information to increase efficiency and reveal general patterns. Yet, this simplification also forfeits information, thereby reducing representational capacity.…

Functional connectivity (FC) refers to the investigation of interactions between brain regions to understand integration of neural activity in several regions. FC is often estimated using functional magnetic resonance images (fMRI). There…

Applications · Statistics 2023-01-24 Nathan Tung , Jerome Sanes , Eli Upfal , Ani Eloyan

Perceptions and actions, thoughts and memories result from coordinated activity in hundreds or even thousands of neurons in the brain. It is an old dream of the physics community to provide a statistical mechanics description for these and…

Disordered Systems and Neural Networks · Physics 2024-09-04 Leenoy Meshulam , William Bialek

Understanding how the brain learns to compute functions reliably, efficiently and robustly with noisy spiking activity is a fundamental challenge in neuroscience. Most sensory and motor tasks can be described as dynamical systems and could…

Neurons and Cognition · Quantitative Biology 2017-05-24 Sophie Denève , Alireza Alemi , Ralph Bourdoukan

In the context of agent based modeling and network theory, we focus on the problem of recovering behavior-related choice information from origin-destination type data, a topic also known under the name of network tomography. As a basis for…

Physics and Society · Physics 2015-08-24 Tiziano Squartini , Enrico Ser-Giacomi , Diego Garlaschelli , George Judge

Understanding the complexity of biological neural networks like the human brain is one of the scientific challenges of our century. The organization of the brain can be described at different levels, ranging from small neural networks to…

Neurons and Cognition · Quantitative Biology 2018-05-23 Stefano De Blasi