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Autonomous scientific research, capable of independently conducting complex experiments and serving non-specialists, represents a long-held aspiration. Achieving it requires a fundamental paradigm shift driven by artificial intelligence…

Artificial Intelligence · Computer Science 2025-07-04 Mingyu Wu , Zhaoguo Wang , Jiabin Wang , Zhiyuan Dong , Jingkai Yang , Qingting Li , Tianyu Huang , Lei Zhao , Mingqiang Li , Fei Wang , Chunhai Fan , Haibo Chen

We present a novel approach for constructing discrete optimization benchmarks that enables fine-grained control over problem properties, and such benchmarks can facilitate analyzing discrete algorithm behaviors. We build benchmark problems…

Neural and Evolutionary Computing · Computer Science 2026-04-09 Furong Ye , Frank Neumann , Thomas Bäck , Niki van Stein

Recent advances in computing hardware and modeling software have given rise to new applications for numerical optimization. These new applications occasionally uncover bottlenecks in existing optimization algorithms and necessitate further…

Mathematical Software · Computer Science 2024-10-18 Anugrah Jo Joshy , John T. Hwang

NUBO, short for Newcastle University Bayesian Optimisation, is a Bayesian optimization framework for the optimization of expensive-to-evaluate black-box functions, such as physical experiments and computer simulators. Bayesian optimization…

Machine Learning · Computer Science 2026-04-29 Mike Diessner , Kevin J. Wilson , Richard D. Whalley

Deep learning models that leverage large datasets are often the state of the art for modelling molecular properties. When the datasets are smaller (< 2000 molecules), it is not clear that deep learning approaches are the right modelling…

Computational Engineering, Finance, and Science · Computer Science 2022-12-07 Gary Tom , Riley J. Hickman , Aniket Zinzuwadia , Afshan Mohajeri , Benjamin Sanchez-Lengeling , Alan Aspuru-Guzik

In today's uncertain and competitive market, where enterprises are subjected to increasingly shortened product life-cycles and frequent volume changes, reconfigurable manufacturing systems (RMS) applications play a significant role in the…

Systems and Control · Electrical Eng. & Systems 2023-01-02 Carlos Alberto Barrera-Diaz , Amir Nourmohammdi , Henrik Smedberg , Tehseen Aslam , Amos H. C. Ng

Recently, the impressive performance of large language models (LLMs) on a wide range of tasks has attracted an increasing number of attempts to apply LLMs in drug discovery. However, molecule optimization, a critical task in the drug…

Quantitative Methods · Quantitative Biology 2024-01-22 Geyan Ye , Xibao Cai , Houtim Lai , Xing Wang , Junhong Huang , Longyue Wang , Wei Liu , Xiangxiang Zeng

Sampling-based motion planning algorithms have been continuously developed for more than two decades. Apart from mobile robots, they are also widely used in manipulator motion planning. Hence, these methods play a key role in collaborative…

Robotics · Computer Science 2023-07-13 Carl Gaebert , Sascha Kaden , Benjamin Fischer , Ulrike Thomas

We present the software system developed to implement the Locus Algorithm, a novel algorithm designed to maximise the performance of differential photometry systems by optimising the number and quality of reference stars in the Field of…

Instrumentation and Methods for Astrophysics · Physics 2020-03-12 Kevin Nolan , Eugene Hickey , Oisín Creaner

Advancements of both computational and experimental tools have recently led to significant progress in the development of new advanced and functional materials, paralleled by a quick growth of the overall amount of data and information on…

Materials Science · Physics 2024-12-25 Fabio Le Piane , Matteo Baldoni , Mauro Gaspari , Francesco Mercuri

This paper presents OpTaS, a task specification Python library for Trajectory Optimization (TO) and Model Predictive Control (MPC) in robotics. Both TO and MPC are increasingly receiving interest in optimal control and in particular…

Planning is central to agents and agentic AI. The ability to plan, e.g., creating travel itineraries within a budget, holds immense potential in both scientific and commercial contexts. Moreover, optimal plans tend to require fewer…

Artificial Intelligence · Computer Science 2025-04-22 Haoming Li , Zhaoliang Chen , Jonathan Zhang , Fei Liu

Chemists need to perform many laborious and time-consuming experiments in the lab to discover and understand the properties of new materials. To support and accelerate this process, we propose a robot framework for manipulation that…

Recent advancements in large language models (LLMs) have led to significant breakthroughs in mathematical reasoning capabilities. However, existing benchmarks like GSM8K or MATH are now being solved with high accuracy (e.g., OpenAI o1…

We provide several quantum algorithms for continuous optimization that do not require gradient estimation. Instead, we encode the optimization problem into the dynamics of a physical system and coherently simulate the time evolution. We…

Quantum Physics · Physics 2026-03-18 Ahmet Burak Catli , Sophia Simon , Nathan Wiebe

This paper introduces DOoM, a new open-source benchmark designed to assess the capabilities of language models in solving mathematics and physics problems in Russian. The benchmark includes problems of varying difficulty, ranging from…

Artificial Intelligence · Computer Science 2025-11-14 Ilya Kuleshov , Ilin Pavel , Nikolay Kompanets , Ksenia Sycheva , Aleksandr Nikolich

Parallelization is a popular strategy for improving the performance of iterative algorithms. Optimization methods are no exception: design of efficient parallel optimization methods and tight analysis of their theoretical properties are…

Optimization and Control · Mathematics 2023-11-28 Alexander Tyurin , Peter Richtárik

The rapid adoption of LLMs in both research and industry highlights the challenges of deploying them safely and reveals a gap in the systematic evaluation of toxicity benchmarks. As organizations increasingly rely on these benchmarks to…

Artificial Intelligence · Computer Science 2026-05-12 Regina Gugg , Selina Niederländer , Andreas Stöckl , Martin Flechl

We present Octopus, an AI agent to jointly balance three conflicting task objectives on a micro-crowdsourcing marketplace - the quality of work, total cost incurred, and time to completion. Previous control agents have mostly focused on…

Artificial Intelligence · Computer Science 2017-08-16 Karan Goel , Shreya Rajpal , Mausam
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