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Brain age is the estimate of biological age derived from neuroimaging datasets using machine learning algorithms. Increasing brain age with respect to chronological age can reflect increased vulnerability to neurodegeneration and cognitive…

Quantitative Methods · Quantitative Biology 2024-02-13 Saurabh Sihag , Gonzalo Mateos , Alejandro Ribeiro

Brain age prediction based on neuroimaging data could help characterize both the typical brain development and neuropsychiatric disorders. Pattern recognition models built upon functional connectivity (FC) measures derived from resting…

Computer Vision and Pattern Recognition · Computer Science 2018-01-15 Hongming Li , Theodore D. Satterthwaite , Yong Fan

Numerous studies have established that estimated brain age, as derived from statistical models trained on healthy populations, constitutes a valuable biomarker that is predictive of cognitive decline and various neurological diseases. In…

Computer Vision and Pattern Recognition · Computer Science 2019-07-02 Xinyang Feng , Zachary C. Lipton , Jie Yang , Scott A. Small , Frank A. Provenzano

In this work, deep learning techniques for brain age prediction from magnetic resonance images are investigated, aiming to assist in the identification of biomarkers of the natural aging process. The identification of biomarkers is useful…

Image and Video Processing · Electrical Eng. & Systems 2021-12-24 Victor H. R. Oliveira , Augusto Antunes , Alexandre S. Soares , Arthur D. Reys , Robson Z. Júnior , Saulo D. S. Pedro , Danilo Silva

Deep Learning for neuroimaging data is a promising but challenging direction. The high dimensionality of 3D MRI scans makes this endeavor compute and data-intensive. Most conventional 3D neuroimaging methods use 3D-CNN-based architectures…

Image and Video Processing · Electrical Eng. & Systems 2021-02-10 Umang Gupta , Pradeep K. Lam , Greg Ver Steeg , Paul M. Thompson

Lesion detection in brain Magnetic Resonance Images (MRIs) remains a challenging task. MRIs are typically read and interpreted by domain experts, which is a tedious and time-consuming process. Recently, unsupervised anomaly detection (UAD)…

Image and Video Processing · Electrical Eng. & Systems 2022-02-01 Marcel Bengs , Finn Behrendt , Max-Heinrich Laves , Julia Krüger , Roland Opfer , Alexander Schlaefer

The most recent fast and accurate image segmentation methods are built upon fully convolutional deep neural networks. In this paper, we propose new deep learning strategies for DenseNets to improve segmenting images with subtle differences…

Computer Vision and Pattern Recognition · Computer Science 2018-12-11 Seyed Raein Hashemi , Sanjay P. Prabhu , Simon K. Warfield , Ali Gholipour

The human brain undergoes rapid development during the third trimester of pregnancy. In this work, we model the neonatal development of the infant brain in this age range. As a basis, we use MR images of preterm- and term-birth neonates…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Florentin Bieder , Paul Friedrich , Hélène Corbaz , Alicia Durrer , Julia Wolleb , Philippe C. Cattin

Exploring the developing brain is a major issue in understanding what enables children to acquire amazing abilities, and how early disruptions can lead to a wide range of neurodevelopmental disorders. MRI plays a key role here by providing…

Neurons and Cognition · Quantitative Biology 2024-01-01 Jessica Dubois

MRI-based brain age estimation models aim to assess a subject's biological brain age based on information, such as neuroanatomical features. Various factors, including neurodegenerative diseases, can accelerate brain aging and measuring…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Simon Joseph Clément Crête , Marta Kersten-Oertel , Yiming Xiao

Timely, accurate and reliable assessment of fetal brain development is essential to reduce short and long-term risks to fetus and mother. Fetal MRI is increasingly used for fetal brain assessment. Three key biometric linear measurements…

Image and Video Processing · Electrical Eng. & Systems 2022-06-30 Netanell Avisdris , Bossmat Yehuda , Ori Ben-Zvi , Daphna Link-Sourani , Liat Ben-Sira , Elka Miller , Elena Zharkov , Dafna Ben Bashat , Leo Joskowicz

The rapid increment of morbidity of brain stroke in the last few years have been a driving force towards fast and accurate segmentation of stroke lesions from brain MRI images. With the recent development of deep-learning, computer-aided…

Image and Video Processing · Electrical Eng. & Systems 2021-10-25 Hritam Basak , Rukhshanda Hussain , Ajay Rana

Age estimation is a classic learning problem in computer vision. Many larger and deeper CNNs have been proposed with promising performance, such as AlexNet, VggNet, GoogLeNet and ResNet. However, these models are not practical for the…

Computer Vision and Pattern Recognition · Computer Science 2019-04-12 Chao Zhang , Shuaicheng Liu , Xun Xu , Ce Zhu

Brain extraction or whole brain segmentation is an important first step in many of the neuroimage analysis pipelines. The accuracy and robustness of brain extraction, therefore, is crucial for the accuracy of the entire brain analysis…

Computer Vision and Pattern Recognition · Computer Science 2017-06-21 Seyed Sadegh Mohseni Salehi , Deniz Erdogmus , Ali Gholipour

We introduce here a fully automated convolutional neural network-based method for brain image processing to Detect Neurons in different brain Regions during Development (DeNeRD). Our method takes a developing mouse brain as input and i)…

Computer Vision and Pattern Recognition · Computer Science 2018-07-11 Asim Iqbal , Asfandyar Sheikh , Theofanis Karayannis

Using 3D CNNs on high resolution medical volumes is very computationally demanding, especially for large datasets like the UK Biobank which aims to scan 100,000 subjects. Here we demonstrate that using 2D CNNs on a few 2D projections…

Image and Video Processing · Electrical Eng. & Systems 2023-03-14 Johan Jönemo , Muhammad Usman Akbar , Robin Kämpe , J Paul Hamilton , Anders Eklund

Over the years, Machine Learning models have been successfully employed on neuroimaging data for accurately predicting brain age. Deviations from the healthy brain aging pattern are associated to the accelerated brain aging and brain…

Image and Video Processing · Electrical Eng. & Systems 2023-06-23 M. Tanveer , M. A. Ganaie , Iman Beheshti , Tripti Goel , Nehal Ahmad , Kuan-Ting Lai , Kaizhu Huang , Yu-Dong Zhang , Javier Del Ser , Chin-Teng Lin

Purpose: To implement a brain segmentation pipeline based on convolutional neural networks, which rapidly segments 3D volumes into 27 anatomical structures. To provide an extensive, comparative study of segmentation performance on various…

Image and Video Processing · Electrical Eng. & Systems 2020-08-12 Jonathan Zopes , Moritz Platscher , Silvio Paganucci , Christian Federau

Preterm infants (born between 28 and 37 weeks of gestation) face elevated risks of neurodevelopmental delays, making early identification crucial for timely intervention. While deep learning-based volumetric segmentation of brain MRI scans…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Lexin Ren , Jiamiao Lu , Weichuan Zhang , Benqing Wu , Tuo Wang , Yi Liao , Jiapan Guo , Changming Sun , Liang Guo

Purpose: To develop an age prediction model which is interpretable and robust to demographic and technological variances in brain MRI scans. Materials and Methods: We propose a transformer-based architecture that leverages self-supervised…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Pengyu Kan , Craig Jones , Kenichi Oishi