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Related papers: Parameter Estimation for Mixed-Mechanism Tear Film…

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Purpose: To determine whether evaporation, tangential flow, or a combination of the two cause tear film breakup in a variety of instances; to estimate related breakup parameters that cannot be measured in breakup during subject trials; and…

Fluid Dynamics · Physics 2022-11-10 Rayanne A. Luke , Richard J. Braun , Carolyn G. Begley

The tear film (TF) plays a critical role in maintaining ocular surface health, and its disruption through tear breakup (TBU) is closely associated with dry eye disease. Evaporation-driven thinning is a primary mechanism underlying TBU, yet…

Numerical Analysis · Mathematics 2026-05-05 Qinying Chen , Tobin Driscoll

Fluorescein is perhaps the most commonly used substance to visualize tear film thickness and dynamics; better understanding of this process aids understanding of dry eye syndrome which afflicts millions of people. We study a mathematical…

Quantitative Methods · Quantitative Biology 2016-11-01 Longfei Li , R. J. Braun , W. D. Henshaw , P. E. King-Smith

The contribution of different physical effects to tear breakup (TBU) in subjects with no self-reported history of dry eye are quantified. An automated system using a convolutional neural network is deployed on fluorescence (FL) imaging…

Evaporation profiles have a strong effect on tear film thinning and breakup (TBU), a key factor in dry eye disease (DED). In experiments, TBU is typically seen to occur in patterns that locally can be circular (spot), linear (streak), or…

Numerical Analysis · Mathematics 2024-08-30 Qinying Chen , Tobin A. Driscoll , Richard J. Braun

The rupture of a liquid film due to co-flowing turbulent shear flows in the gas phase is studied using a volume-of-fluid method. To simulate this multiphase problem, we use a simplified numerical setup where the liquid film is 'sandwiched'…

Fluid Dynamics · Physics 2021-02-23 Melissa Kozul , Pedro S. Costa , James R. Dawson , Luca Brandt

One of the main roles of the lipid layer (LL) of the tear film (TF) is to help prevent evaporation of the aqueous layer (AL). The LL thickness, composition, and structure all contribute to its barrier function. It is believed that the lipid…

Fluid Dynamics · Physics 2024-04-29 M. J. Taranchuk , R. J. Braun

The human tear film (TF) is thin multilayer fluid film that is critical for clear vision and ocular surface health. Its dynamics are strongly affected by a floating lipid layer and, in health, that layer slows evaporation and helps create a…

Fluid Dynamics · Physics 2024-04-23 M. J. Taranchuk , R. J. Braun

Atmospheric turbulence and aero-optic effects cause phase aberrations in propagating light waves, thereby reducing effectiveness in transmitting and receiving coherent light from an aircraft. Existing optical sensors can measure the…

Signal Processing · Electrical Eng. & Systems 2026-02-12 Jeffrey W. Utley , Gregery T. Buzzard , Charles A. Bouman , Matthew R. Kemnetz

It is commonly accepted that the breakup criteria of drops or bubbles in turbulence is governed by surface tension and inertia. However, also {\it{buoyancy}} can play an important role at breakup. In order to better understand this role,…

Fluid Dynamics · Physics 2022-05-24 Hao-Ran Liu , Kai Leong Chong , Qi Wang , Chong Shen Ng , Roberto Verzicco , Detlef Lohse

The deformation and breakup of droplets in airflows is important in spray and atomisation processes, but the shear effect in non-uniform airflow is rarely reported. In this study, the deformation and breakup of droplets in a shear flow of…

Fluid Dynamics · Physics 2023-01-18 Zhikun Xu , Tianyou Wang , Zhizhao Che

Breakup of drop/bubble can be viewed as a result of fundamental force balance when the disruptive force is greater than the restorative force. A disruptive force acting on the drop/bubble tries to deform it, whereas a restorative force…

Fluid Dynamics · Physics 2017-01-24 Suhas Jain S

Aerobreakup of fluid droplets under the influence of impulsively generated high-speed gas flow using an open-ended shock tube is studied using experiments and numerical simulations. Breakup of mm-sized droplets at high Weber number was…

Fluid Dynamics · Physics 2022-06-24 James Leung , Mohana Gurunadhan , Shyam Menon

This work presents a mathematical model for the optimal control of thin-film flows over a flexible topography influenced by an external force. Our thin-film model allows for the rupture of films as well as the coalescence of bubbles. The…

Optimization and Control · Mathematics 2025-06-19 S. Alrashidy , A. Kalogirou , D. Kalise , K. G. van der Zee

The Marangoni contraction of sessile droplets occurs when a binary mixture of volatile liquids is placed on a high-energy surface. Although the surface is wetted completely by the mixture and its components, a quasi-stationary non-vanishing…

Fluid Dynamics · Physics 2022-02-01 Olinka Ramirez-Soto , Stefan Karpitschka

The effects of elasticity on filament thinning and breakup are investigated in microchannel cross flow. When a viscous solution is stretched by an external immiscible fluid, a low 100 ppm polymer concentration strongly affects the breakup…

Fluid Dynamics · Physics 2008-04-14 P. E. Arratia , J. P. Gollub , D. J. Durian

Dry Eye Disease (DED) is one of the most common ocular diseases: over five percent of US adults suffer from DED. Tear film instability is a known factor for DED, and is thought to be regulated in large part by the thin lipid layer that…

Computer Vision and Pattern Recognition · Computer Science 2022-12-08 Tejasvi Kothapalli , Charlie Shou , Jennifer Ding , Jiayun Wang , Andrew D. Graham , Tatyana Svitova , Stella X. Yu , Meng C. Lin

Rupture is a nonlinear instability resulting in a finite-time singularity as a fluid layer approaches zero thickness at a point. We study the dynamics of rupture in a generalized mathematical model of thin films of viscous fluids with…

Mathematical Physics · Physics 2017-01-05 Hangjie Ji , Thomas Witelski

In this paper, we present a theoretical study aimed at investigating the rate-limiting factors in thin-film evaporative heat transfer processes, considering the finite-rate evaporation kinetics. The problems of evaporation of a flat…

Fluid Dynamics · Physics 2024-05-31 H. Zhao , R. Poole , Z. Zhou

The distribution of liquid water in ice-free clouds determines their radiative properties, a significant source of uncertainty in weather and climate models. Evaporation and turbulent mixing cause a cloud to display large variations in…

Fluid Dynamics · Physics 2021-06-02 J. Fries , G. Sardina , G. Svensson , B. Mehlig
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